Unfortunately, for some serious illnesses, patients require parenteral nutrition. Only in this way can the body receive a sufficient amount of nutrients. Often, for this, in modern medicine, the Aminosol Neo solution is used, which helps maintain normal cell activity. Of course, patients are interested in additional information about the drug.
The drug "Aminosol Neo": photo, composition and form of release
Of course, to begin with, it is worthwhile to understand the composition and form of the drug. What is Aminosol Neo? The description provided in the official instructions suggests that the medicine is used for parenteral nutrition and contains the necessary electrolytes and amino acids in the body.
In particular, the composition contains more than a dozen amino acids in the form of L-isomers, including methionine, arginine, alanine, proline, histidine, tyrosine, phenylalanine, tryptophan, serine, leucine, valine, isoleucine, lysine monoacetate. As auxiliary components, purified water and glacial acetic acid are used.
Aminosol Neo is available in the form of a solution for intravenous administration. It is transparent, colorless, but sometimes has a yellow or even brown tint. In the pharmacy, you can buy the drug in glass bottles with a volume of 500 ml.
In some cases, patients are prescribed a solution of Aminosol Neo-E, which in addition to a complex of amino acids also contains a set of electrolytes, including sodium, calcium, potassium, chlorine, magnesium, glycerophosphate and some other ions.
By the way, you can buy solution bottles only in stationary hospital departments and only with a doctor’s prescription - they don’t sell the drug at ordinary drugstores. It is better to store it in a cool room, protecting it from direct sunlight (a temperature of 15-25 ° C is considered optimal). Shelf life - 2 years from the date of production.
In which cases the drug is used: indications
As already mentioned, the drug is widely used in modern medicine for partial or complete parenteral nutrition. In particular, indications for the procedure are:
- hypermetabolic conditions, including severe injuries, sepsis, massive burns;
- severe forms of diseases of the digestive system, including pancreatitis, the presence of fistulas and inflammation in the intestinal wall, obstruction, malabsorption, in a word, those situations in which normal nutrition is impossible;
- the drug is used to saturate the body with useful substances before surgery and in the postoperative period;
- oncological diseases sometimes also do not allow patients to eat intestinally.
The medicine "Aminosol Neo": instructions for use
Only a doctor can choose the right drug for the patient and determine the dosage. The official instruction for the drug "Aminosol Neo" contains only general recommendations, leaving the specialist with the right to adjust the treatment regimen.
The solution is administered by infusion into one of the central veins. The dosage depends on many factors, including the concentration of the drug itself and the patient's body weight. If we are talking about the use of a 10% solution, then the daily dose is 10-20 ml per kilogram of body (20 ml is the maximum permissible dose). It is recommended to inject liquid at a speed of 20-35 drops per minute (not faster).
With the introduction of a solution with a concentration of 15%, the daily dose is 6.7-13.3 ml per kilogram of patient body weight. People whose body weight is 70 kg are injected, as a rule, from 470 to 930 ml of solution per day at a rate of 16 drops per minute.
A sick person must be under the supervision of a doctor or nurse. For patients with renal failure, the dosage changes - about 6-10 ml of solution per day (per kilogram of body) is indicated. In people with liver failure, the protein requirement is also less - they are injected from 8 to 11 ml per kg.
Contraindications to therapy
Can all patients be prescribed Aminosol Neo? The instruction says that some restrictions still exist. Here is a list of them:
- severe forms of hepatic and renal failure;
- shock conditions;
- metabolic acidosis;
- oxygen deficiency;
- decompensated stage of heart failure.
This drug is not prescribed for women during the period of bearing and feeding the child (if there is a need to use the solution during lactation, breastfeeding should be stopped for a while).
Has a medicine and age restrictions. Its effect has not been studied in a group of children and adolescents under the age of 18 years, so the consequences of therapy are unknown. In case of diabetes mellitus, liver diseases, arterial hypertension and sepsis, the medicine can be used, but very carefully - the patient should be under the constant supervision of medical personnel.
What side effects are possible?
According to the reviews of doctors, the drug "Aminosol Neo" in most cases is well tolerated by the body. Adverse reactions, as a rule, occur when the dosage is incorrect or the rules of administration are not followed.
If the solution is administered too quickly, patients experience tachycardia, nausea, vomiting, increased sweating. In cases where, along with this medicine, the patient takes additional amino acid preparations, allergic reactions can develop, including the appearance of a skin rash and itching, shortness of breath and bronchospasm. The consequences can also include a sharp decrease in blood pressure (up to a shock state).
All of the above symptoms disappear if you stop taking the medicine. Against the background of therapy, a decrease in the level of folates in the body is often observed, so patients are always additionally prescribed folic acid.
When introduced into the peripheral vessel, irritation of its walls is possible. There is a likelihood of infection of wounds remaining after infusion, so you must follow all sanitary standards and carefully monitor the patient's condition.
Overdose and its symptoms
Cases of overdose are known. The introduction of too much solution is accompanied by severe nausea, which often ends with vomiting. Other signs include a sharp increase in body temperature, as well as tachycardia. In some patients, there is a violation of the electrolyte composition of plasma.
It is worth saying right away that the above disorders are reversible. Discontinuation of therapy or a decrease in the amount of the drug leads to the disappearance of all signs. In some cases, symptomatic therapy is carried out depending on the violations present.
Additional Information
The solution should not be mixed with other drugs and administered simultaneously. It is worth noting that drug interaction is possible. For example, the medicine "Aminosol Neo" is incompatible with thiopental sodium. With the simultaneous use of arginine (a component of the drug) and spironolactone in patients, the development of severe hyperkalemia is observed.
While taking the drug with aminophylline and some diuretics, the level of insulin in the blood rises. If you are taking oral hormonal contraceptives, you should also inform your doctor about this, since combined use can cause an increase in the amount of growth hormone produced.
If we are talking about treating patients with diabetes mellitus, then against the background of parenteral nutrition with this solution, patients need to inject insulin - this applies to people with the first and second type of diabetes (even if before that there was no need to use synthetic insulin).
Analogs and prices of medicines
Not everyone fits with Aminosol Neo. Analogues of this medicine, of course, exist. Many doctors prescribe such solutions for parenteral nutrition as Aminoven and Aminol as a replacement. Good analogues are also considered “Aminosteril”, “Hepasol”, “Kabiven”, “Infekhol”. Many of them are also used in pediatrics to treat premature babies.
Of course, only a doctor can choose a substitute - independent use of any nutrient solution can only do harm.
As for the cost, the solution bottle will cost about 650-800 rubles, depending on the place of purchase and the manufacturer.
Advantages and disadvantages of the drug: reviews of specialists and patients
What do doctors say about Aminosol Neo? Reviews are mostly positive. The solution really helps to maintain the normal functioning of the patient's body, restores the balance of electrolytes. Therapy most often goes smoothly, without any complications, and there are not so many contraindications.
Patients also note the absence of side effects and discomfort during infusion. Unfortunately, the cost of the drug is high, and to complete the full course requires several bottles, which can be attributed to the shortcomings of the drug. But the positive effect of the treatment really is, and health is more expensive than any money. In any case, in such severe conditions in which the patient needs parenteral nutrition, you must strictly follow all the recommendations of the treating specialist.