The drug "Flamax Forte" many experts position as a wonderful therapeutic agent that instantly removes unpleasant pain, prevents the development of the inflammatory process and lowers body temperature. Specialists often recommend it to patients who suffer from diseases of the musculoskeletal system. Read more about this medicine.
Brief description of the drug "Flamax Forte"
Probably not everyone knows what the above remedy helps from. It turns out that this medicine has antipyretic and anti-inflammatory abilities.
The drug "Flamax Forte" ("Ketoprofen" - another international name) has three forms of release:
- solution;
- blue-colored tablets with a biconvex form, which are coated with a film membrane;
- capsules with white powder of uniform consistency inside.
The capsule contains 50 mg of ketoprofen (the main active ingredient), lactose monohydrate, silicon dioxide, sodium lauryl sulfate, povidone, sodium croscamellose.
One tablet of the above medicine contains 100 mg of ketoprofen, macrogol 6000, talc, titanium dioxide, hypromellose, rice starch, croscamellose sodium, lactose monohydrate, sodium lauryl sulfate, povidone.
The composition of the ampoule of this drug (2 ml) includes 100 mg of ketoprofen, propylene glycol, ethanol, benzyl alcohol, water for injection, sodium hydroxide.
Only with a special recipe can you buy the drug "Flamax Forte." Pills, reviews of which are mostly positive, cost 141 rubles. for 20 pcs. The cost of packing ampoules is 210 rubles. The price of capsules of the above drug is 125 rubles.
Keep this medicine away from children and preferably in a place where there is no direct sunlight, at normal room temperature.
pharmachologic effect
The drug "Flamax Forte", the photo of which is provided below, produces the following effects on the patient's body:
- antipyretic;
- anti-aggregation;
- anti-inflammatory;
- analgesic.
Ketoprofen with blood proteins binds to 99% with albumin in the patient's body. It should be noted that after taking the drug, the concentration of the main substance in the plasma is reached quite quickly.
Ketoprofen has the ability to enter the synovial fluid and connective tissue. After a single injection of the drug intramuscularly, after a quarter of an hour, a sufficiently high concentration is observed in the synovial fluid. It persists for more than a day (about 30 hours). During this time, it is quite well able to reduce stiffness in the joints and pain in them.
Ketoprofen is metabolized mainly in the liver. The glucuronidation process is also carried out as a result of which glucuronic acid and esters are formed. Further, these substances are successfully excreted by the kidneys.
Indications for use
The medicine "Flamax Forte", the instructions for use recommend taking with the symptoms of the following diseases:
- rheumatoid arthritis;
- osteoarthrosis;
- gouty arthritis;
- myalgia;
- psoriatic arthritis;
- radiculitis;
- ossalgia;
- otitis;
- bursitis;
- arthralgia;
- tendonitis;
- neuralgia;
- radiculitis;
- toothache;
- oncological diseases;
- headache;
- algodismenorea.
It should be noted that the drug "Flamax Forte" instructions for use also recommends use in the treatment of postoperative and post-traumatic pain syndrome. In addition, the above drug is used at birth as a tocolytic and analgesic.
Contraindications
Flamax Forte tablets are not recommended by specialists and instructions if the patient suffers from diseases such as:
- hypersensitivity to individual ingredients of the drug;
- kidney disease, which are in a progressive state;
- hyperkalemia
- gastroduodenitis during exacerbation;
- violation of blood formation;
- an ulcer during an exacerbation;
- violation of hemostasis;
- gastrointestinal erosion during exacerbation;
- severe liver failure.
The instruction "Flamax Forte" also does not recommend use in the third trimester of pregnancy and during breastfeeding. It is forbidden to use the above medicine for patients after coronary artery bypass grafting and with a combination of recurrent nasal polyposis and bronchial asthma with intolerance to NSAIDs.
It should be remembered that for the treatment of children under 15 years of age, using the drug “Flamax Forte”, the photo of which is provided below, is not recommended.
With great caution, this tool should be used for the treatment of patients who suffer from hypertension, bronchial asthma, edema, severe dental diseases, diabetes mellitus, renal failure, sepsis, and chronic heart failure.
Mode of application
Flamax Forte injections are administered intramuscularly as well as intravenously. The latter is carried out exclusively in a hospital. On average, an infusion of a substance (infusion) lasts about one and a half hours. The maximum time for administration of the drug is 48 hours.
In this case, the dose of the above funds should not exceed 300 mg. If the infusion is short, 100-200 mg of the drug should be diluted in a 0.9% solution of sodium chloride in an amount of 100 ml. Such an infusion of funds is carried out no more than one hour.
The next infusion of this drug is allowed only after 8 hours. If the infusion of a therapeutic agent is continuous, then it is important to dilute it in half a liter of a special solution.
Intramuscularly, the above drug is administered a maximum of 2 times a day in an amount of 100 mg.
Capsules of the drug “Flamax Forte” are allowed to be used exclusively by patients in the process of eating a maximum of 2 pcs. in one go. Depending on the course of the disease, the doctor determines the desired dosage for a particular patient. The maximum rate of medication per day is about 300 mg.
Flamax Forte tablets should also be taken with meals. At one time, the patient is instructed to take a pill at most 3 times a day.
Experts note that an overdose of the above medicine is not too dangerous. It is accompanied by the following symptoms:
- shortness of breath
- dizziness
- abdominal pains;
- bleeding
- headache;
- vomiting.
Treatment in this case is prescribed symptomatic. That is, the patient should first do a gastric lavage and prescribe the intake of sorbents.
special instructions
Patients should remember and strictly observe some precautions:
- simultaneous therapy with the aforementioned drug and Warfarin means requires strict medical supervision;
- this medicine perfectly masks the symptoms of many infectious diseases;
- during treatment, it is important for the patient to monitor peripheral blood counts;
- you need to carefully monitor the work of the kidneys and liver when therapy is carried out using the drug "Flamax Forte";
- expert reviews and instructions recommend that you do not practice long-term treatment with the above tool and use it in minimal quantities to reduce the risk of side effects from the digestive system;
- if it is necessary to determine 17-ketosteroids, the patient should cancel this drug within two days (that is, 48 hours);
- in some cases, during treatment with Flamax Forte, the patient’s attention concentration may deteriorate (this should be remembered when driving vehicles).
Side effects
Specialists note that in some cases, some patients experienced serious side effects when using the above medication. Scientists admit that their appearance may be associated with the action of ketoprofen.
So, this medicine may cause the following side effects:
- dyspepsia, gastritis, belching, abdominal pain, diarrhea, nausea, constipation, stomatitis, vomiting, anorexia, increased appetite, rectal bleeding, dry mouth, gastrointestinal perforation, liver dysfunction, melena, excessive thirst, hematomesis, peptic ulcer, occult bleeding, intestinal ulceration, cholestatic hepatitis, salivation;
- nervousness, dizziness, visual impairment, vertigo, hearing loss, taste impairment, retinal hemorrhage, conjunctivitis, malaise, amnesia, pigmentation changes, CNS depression, confusion, eye pain, unusual dreams, insomnia;
- peripheral vascular disease, increased arterial pressure, anemia, agranulocytosis, increased heart rate, hypocoagulation, thrombocytopenia, worsening heart failure, hemolysis, tachycardia;
- dyspnea, rhinitis, nosebleeds, hemoptysis, laryngeal edema, pharyngitis, bronchospasm;
- increased blood urea nitrogen, impaired normal functioning of the liver, edema, hematurgy, menometrorrhagia, interstitial nephritis, renal failure, nephrotic syndrome;
- alopecia (alopecia) rash on the skin, pruritis, eczema, purpura, anaphylaxis, excessive sweating, myalgia, weight gain, allergic reactions.
Experts warn that when observing the symptoms of the above diseases, the patient should definitely visit a doctor and tell him about a health problem. This medicine should be discontinued.
Interaction with other drugs
If during treatment with the above drug the patient takes other drugs, he needs to inform the doctor about it.
It should be remembered that the above tool enhances the nephrotoxic effect of loop diuretics. In addition, the effectiveness of uricosuric drugs is significantly reduced while their use with Flamax Forte tablets.
Reviews of experts also note that the above drug enhances the effects of ethanol, anticoagulants, antiplatelet agents, fibrinolytics.
With the simultaneous combination of Flamax Forte medication with corticotropin, GCS, ethanol, NSAIDs, the patient may suddenly experience bleeding in the gastrointestinal tract, ulcers will appear, and renal function will be impaired .
The drug "Flamax Forte" reduces the effectiveness of the influence of diuretics and antihypertensive drugs.
Bleeding can also occur if you use the above medication at the same time with the following remedies:
- Heparin.
- Thrombolytics.
- Cefotetan.
- "Cefoperazone".
- Antiplatelet agents.
- Cefamandol.
During therapy with this drug, it is very important for the doctor to recalculate the doses of hypoglycemic agents, including insulin, because their effect is significantly increased.
In addition, the above drug increases the hematotoxicity of myelotoxicity agents. Also, this drug increases the concentration in the blood of verapamil, nifedipine, methotrexate, lithium preparations.
The absorption of Flamax Forte decreases if it is included in therapy with antacids and colestyramines.
If you mix the above drug with tramadol in one bottle, then a small precipitate forms.
The drug "Flamax Forte": analogues
Sometimes situations arise when the patient simply needs to know the analogues of the above drugs. This may be due to the fact that the pharmacy temporarily lacks the necessary drug, or, for example, does not suit the cost of Flamax Forte. Indications for use, which are listed above, can also be for the following drugs:
- "Fastum gel";
- "Arketal";
- "Profenid";
- "Artrum";
- Bystrumgel;
- Ketonal;
- Ketosprey;
- Ketonal Uno;
- "Arthrosilen";
- Ketonal Duo ;
- "Oruvel";
- "Flexen".
It should be noted that they produce the same therapeutic effect on the patient’s body as the Flamax Forte drug. But before using a substitute for this medication, you need to consult your doctor.
Reviews about the drug
About the above drug, satisfied patients leave a lot of positive feedback. People claim that this medicine is simply an excellent painkiller. For example, a woman writes about the appointment of this drug after surgery to relieve pain. The injection acted instantly, she almost immediately got to her feet and began to move normally. The woman did not feel pain, there was no discomfort.
Some men write that after grabbing their backs in the country, they could not straighten out. We tried a lot of different tools, but nothing helped. My back hurt terribly. Only Flamax Forte could relieve pain. Their reviews claim that after the first injection, the pain subsided within 20 minutes and did not bother all night. Therefore, this category of patients claims that injections are an excellent tool that maintains a therapeutic effect for a long time.
Also there are responses of people who used the above drug in the course of therapy. People write that this medicine instantly relieves pain in chondosis attacks. But some patients complain that the drug “Flamax Forte”, although it excellently relieves pain, but still in some cases causes side effects. For example, after these injections, weakness occurs in the body and a person wants to lie down a bit. Therefore, if the patient was injected with this therapeutic agent, he needs to at least an hour or two refrain from driving.
The drug "Flamax Forte" is highly effective, in addition, it is completely safe for the patient. It perfectly relieves severe pain, even if it is in an exacerbated period. In addition, the drug perfectly normalizes body temperature and prevents the development of the inflammatory process.