In violation of metabolic processes in the body, deviations in the functioning of all organ systems are observed. First of all, the brain suffers. The pharmaceutical industry produces a large number of drugs to eliminate this problem. One of these are Actovegin tablets, instructions for use, indications for use will be discussed later.
What is the drug
The drug belongs to the group of stimulants of metabolic processes. After a course of therapy, nutrition in the tissues and the removal of glucose from the bloodstream are significantly improved. “Actovegin 200 mg” tablets (instructions for use speak of this) make tissues and organs more resistant to oxygen deficiency. This allows under conditions of oxygen starvation to prevent damage to cellular structures.
Therapeutic effect
Improve energy metabolism, according to the instructions for use, tablets "Actovegin 200 mg." At the level of tissue structures, the following therapeutic effects are observed:
- The synthesis of collagen fibers increases.
- Cell division and their redistribution to areas that need to restore the integrity of the structures is activated.
- Blood supply to tissues and organs improves due to the growth of the blood vessel network.
- The process of repairing damaged structures and tissues, such as cuts, abrasions, ulcers, burns, is accelerated. Against the background of taking Actovegin tablets (the instructions for use contain such information), any wounds heal faster, and the scar is practically not formed.
- Tissue respiration improves, as a result, oxygen is consumed more efficiently. The negative effects of oxygen deficiency are reduced.
- The process of using glucose by cells that are in a state of oxygen starvation is intensifying.
- In the blood, the concentration of glucose decreases, and in the tissues hypoxia decreases.
The process of utilization of glucose molecules plays an important role for the brain, since its structures more than other organs need this substance. Actovegin tablets, the instructions for use of which are enclosed in each package, contain substances similar in action to insulin. The drug improves glucose transport in the brain, cells capture molecules and use them to generate energy.
"Actovegin" normalizes the work of all departments of the nervous system, reducing the severity of cerebral insufficiency syndrome.
The composition of the drug
Actovegin tablets, the instructions for use are very detailed, contain in their composition the main active ingredient - deproteinized hemoderivative, which is obtained from the blood of calves. The mass fraction of the component is 200 mg.
Excipients are available:
- Sucrose.
- Povidone.
- Talc.
- Diethyl phthalate.
- Yellow coloring component.
- Mountain wax.
- Titanium dioxide.
- Acacia gum.
- Hypromellose phthalate.
The composition of the drug provides its properties.
Indications for use
Recommends the use of Actovegin tablets for children and adults to be used for the following pathologies and disorders:
- In the complex treatment of metabolic abnormalities.
- Vascular pathology of the brain.
- In the treatment of traumatic brain injuries.
- In the presence of disorders of the vascular system, for example, deterioration of venous or arterial blood flow.
- Therapy of complications after trophic ulceration.
- Polyneuropathy in patients with diabetes mellitus.
- Stroke.
- To accelerate the healing of ulcers, bedsores.
- Treatment of radiation, thermal, sunburn of varying degrees.
- Encephalopathy of any etiology.
- Angiopathy of diabetic origin.
- Radiation neuropathy.
- Damage to the mucous membranes provoked by radiation damage.
The drug can be used for prophylactic purposes during radiation therapy.
Instructions for use of tablets
Actovegin reviews are positive, but it is important to take the drug correctly. To do this, you must adhere to the following recommendations:
- The drug should be taken before meals.
- Do not chew tablets.
- Usually, the doctor prescribes 1-2 tablets 3 times a day.
- Drink plenty of water.
- If you have a diagnosis of diabetic polyneuropathy, the course of therapy begins with the introduction of 2 g of the drug intravenously for 3 weeks, and then you can switch to taking tablets 2-3 times a day, 1 pc.
The duration of therapy is usually a month and a half, but all at the discretion of the doctor.
The drug in children's practice
Actovegin tablets for children (instructions for use include such information) are prescribed in case of metabolic disorders in the brain, to accelerate metabolic processes, restore tissues and structures in wounds, radiation injuries, and vascular disorders.
The drug is prescribed even for newborns, but not in the form of tablets, but intravenously or intramuscularly in the amount of 0.4-0.5 ml per kilogram of the baby's weight. Children after three years are allowed to take 0.25-0.5 ml once a day.
Maternity Medicine
Tablets "Actovegin" instructions for use for expectant mothers are allowed to take. Doctors to women in position often prescribe a drug in the form of tablets or droppers to improve blood flow, to restore uteroplacental circulation. After a course of therapy, glucose uptake is improved, which contributes to the synthesis of the required amount of energy.
In the course of the studies, the negative effect of Actovegin tablets during pregnancy (the instructions for use informs) on the developing fetus was not established, but in each case it is necessary to take into account the potential harm, therefore, prescribing the medicine is possible only by a doctor.
Despite the fact that the instructions do not indicate contraindications for breastfeeding, it is better not to use the drug without special indications when a woman is breast-feeding a baby.
Contraindications
It is not always possible to use "Actovegin" for therapy, there are some contraindications. Treatment is not permitted if:
- Diagnosed with pulmonary edema.
- The body retains fluid.
- There is an increased sensitivity to the components of the drug.
- There is a diagnosis of decompensated heart failure.
- Anuria or oliguria develops.
- There is fructose intolerance.
- Disrupted absorption of sucrose-isomaltase
If contraindications are not taken into account, especially during pregnancy, Actovegin tablets (instructions for use warns about this) can provoke a lot of negative consequences.
Side effects
Most often, the drug is well tolerated by patients, but everyone has a different body, and one cannot exclude its reactions associated with individual intolerance of the constituent components.
In such cases, you can observe:
- Redness of the skin.
- Rashes on the body.
- Weakness and malaise.
- Nausea and vomiting.
- Headache.
- In severe cases, loss of consciousness.
- Problems in the gastrointestinal tract.
- Stiffness in the chest, shortness of breath, in rare cases - suffocation.
- Increased sweating.
- Fluid retention in the body, which provokes swelling.
- Increased nervous agitation.
- Stiffness of the airways, which can cause difficulties with swallowing food, water.
- Urticaria.
- Anaphylactic shock.
With severe allergic reactions, antihistamines are indicated, but you will have to stop using the drug and choose an analogue with your doctor to continue further treatment.
Overdose symptoms
The drug does not contain substances that could cause serious harm to health, but this does not mean that large doses can be taken in order to achieve a therapeutic effect.
After treatment with large doses, a negative effect on the gastrointestinal tract is not ruled out. Therapy is required symptomatic.
Interaction with other drugs
The drug "Actovegin" can be combined with other drugs. There is no incompatibility information.
Analogues of the drug
We reviewed the instructions for use of Actovegin tablets. There are also analogues of the drug, but before you choose one of them, you need to know the characteristics of the drug, advantages and disadvantages.
Medicines with a similar therapeutic effect include Cortexin. This is a nootropic drug, which contains proteins of the cerebral cortex of animals. Often prescribed in the presence of violations in the work of not only the brain, but also the spinal cord. Available in powder form for the preparation of an injection solution. The advantages of the drug include:
- Possibility of use in cerebral palsy.
- Allowed to babies from birth.
- Quickly normalizes the condition after strokes, traumatic brain injuries.
But there are also disadvantages that almost all patients note: high cost, pain during administration and the inability to purchase the drug without a doctor’s prescription.
Another analogue is Curantil. The drug has myotropic properties and affects platelet aggregation. Doctors recommend this drug for circulatory disorders in the brain, dyscirculatory encephalopathy. Proven effective in the prevention of coronary heart disease. Compared with the previous medicine, it is also available in the form of a dragee. The benefits include:
- The presence of several dosage forms.
- The drug is approved for use in pregnant women.
- It can be used as an immunomodulator.
But there are also disadvantages: there are a lot of adverse reactions, you can not prescribe the drug to children under 12 years of age, it is contraindicated for angina and myocardial infarction.
The next analogue is Solcoseryl. The composition as the main active substance contains blood components of young calves. The drug is used in the treatment of dermatological problems: trophic ulcers, burns, frostbite. The manufacturer produces the drug in different dosage forms: tablets, injection, ointment, gel. The advantages of the drug are as follows:
- A large list of diseases.
- In the form of a dragee, the medicine can be taken in the presence of pathologies of the stomach.
- The gel can be used for eye diseases.
The disadvantages include: a high probability of allergic reactions, a ban on use in children under 18 years of age and the inability to combine with some drugs.
Before choosing any analogue, be sure to consult your doctor.
Reviews about the drug
Very often prescribe Actovegin tablets for children. Reviews (instructions for use should definitely be studied before use) can often be found positive. Mommy notes that drug therapy is successful. Even after traumatic brain injuries, the child recovers quickly. What is important for children's practice, the medicine is well tolerated and does not cause serious side effects.
Future mothers also respond positively about the drug. Some are very difficult to tolerate pregnancy, there is a threat of premature termination, and doctors prescribe Actovegin. This drug has helped many women to inform the baby and give birth to healthy ones. Pregnants also note that in tablets the medicine is much easier to tolerate than in injections, it does not provoke side effects, and does not negatively affect the gastrointestinal tract.
There are good reviews about the medicine and elderly patients who often turn to the attending physician with complaints of headaches, dizziness, distraction, and poor memory. When visiting a neurologist, vascular encephalopathy is diagnosed, in the treatment of which Actovegin helps. There are complaints about the high cost of the drug, but the result of the treatment is worth it. For elderly patients, good drug tolerance is important.
The quality of life directly depends on the state of our body. It is impossible to talk about well-being if there are pathologies of various systems and organs. The functioning of the body depends on the functioning of the cardiovascular system, the supply of oxygen to the brain. At the slightest deviation, “Actovegin” will come to the rescue, which will quickly establish the process of oxygen supply to the brain tissues, improve glucose uptake. But it is better to take the drug on the recommendation of a doctor after a thorough examination.