The drug "Diclofenac" is a modern anti-inflammatory drug designed primarily to eliminate inflammation in case of damage to joints and muscles. Besides? the medicine is also used to lower the temperature in the treatment of tonsillitis.
The mechanism of action of the drug is to block the synthesis of prostaglandins. In the presence of arthritis, arthrosis with severe pain, the use of "Diclofenac" makes it possible to reduce pain.
Feature of the drug and composition
Often, various diseases provoke such symptoms as inflammatory processes, pain, burning, swelling. There are many medications that help eliminate one or more of these symptoms. It is worth noting that Diclofenac injections, which are anti-inflammatory drugs, are quite popular. This drug has a wide range of actions, namely:
- painkiller;
- anti-inflammatory;
- analgesic;
- antipyretic;
- antirheumatic.
Diclofenac injections are intended for intramuscular administration. The main active ingredient is diclofenac. One ampoule with a volume of 3 milliliters contains 75 milligrams of the active ingredient. Among the additional components, sodium hydroxide, benzyl alcohol, acetylcysteine, mannitol, propylene glycol should be distinguished.
Indications for use
Diclofenac injections are used as an anti-inflammatory drug in such cases:
- arthrosis and arthritis;
- rheumatoid polyarthritis;
- sports injuries;
- osteochondrosis;
- osteoarthrosis;
- conjunctivitis;
- myalgia, neuralgia;
- fever.
It is worth noting that this drug can only be used under the supervision of a treating doctor. The drug is used to eliminate inflammation and various manifestations of this process.
Among the main indications of Diclofenac injections is the elimination of inflammatory reactions in the affected area. It is worth noting that this medicine prevents the re-emergence of painful sensations, and also helps to normalize blood circulation, and protects cells from damage. This restores the functionality of the joints and reduces stiffness in the affected area.
The drug reduces the risk of complications, thereby reducing the likelihood of relapse.
The advantage of using Diclofenac injections is the speed of the onset of the therapeutic effect, however, it is worth noting that along with this, the likelihood of side effects is slightly increased. According to the instructions for use, injections much less irritate the gastric mucosa.
Pregnancy and lactation
A situation may arise that a woman who is prescribed a long course of therapy with Diclofenac injections has a pregnancy. In this case, it is necessary to inform the attending doctor about this. According to the instructions, treatment with Diclofenac injections can be carried out in the first and second trimester, but only after consulting a doctor. The decision to use this medication should be made by assessing the ratio of the possible risk to the child and the benefit to the mother.
Since there is a rather high probability of complications in the fetus and woman, it is strictly forbidden to use the drug during the third trimester. Taking this remedy can provoke a weakening of labor, as well as disturbances in the baby (premature closure of the ductus arteriosus).
It is worth noting that the medicine and its decay products can pass into breast milk. If necessary, the appointment of the drug during lactation, breastfeeding should be discontinued.
How to do injections
Be sure to correctly inject the Diclofenac injection into the buttock, since the drug must necessarily enter the thickness of the muscle. There are also several important rules for the use of this tool in the form of injections.
Before injecting Diclofenac intramuscularly, it needs to be slightly warmed up to body temperature. Basically, the ampoule is held in the palms for several minutes, or you can pinch it in the elbow of the arm. It is worth noting that a heated solution relieves painful sensations much faster. When administering the medication, it is advisable to lay the patient on his side, as this will achieve the maximum possible muscle relaxation.
Before starting the procedure, you need to wash your hands. The drug is injected deeply intramuscularly into the upper outer part of the buttock, since in this area there are no nerve trunks and large vessels.
It is strictly forbidden to inject medicine under the skin or into a vein. Diclofenac injections are generally alternated with other types of analgesics. With hepatic and renal colic, injections can be combined with antispasmodics. It is advisable that the patient during treatment be in a hospital under the supervision of a doctor.
Dosage of drug
According to the instructions for the use of Diclofenac injections, the dosage should not exceed 150 mg. The drug in the form of an injection solution is mainly used in a dosage of 75 mg, which equals one ampoule. To obtain a faster result, it is permissible to use a maximum dosage of 150 mg per day. The course of injections "Diclofenac" lasts for 1-5 days. If treatment for some reason requires continuation, the doctor may prescribe the drug in tablet form or in the form of suppositories.
This drug is mainly prescribed by doctors in traumatology and rheumatology. When treating rheumatoid arthritis, the remedy has many advantages over other types of medications, as it helps to eliminate morning stiffness, reduce joint swelling, pain and improve motor activity.
According to the instructions for the use of Diclofenac injections, can the dosage in case of especially severe course of the disease be two injections of this drug, or is a combination of injections with other forms of this medicine carried out, in particular? with rectal suppositories or tablets. With migraine attacks, intramuscular administration of one ampoule of the drug in the form of injections is required, and if necessary, the use of a suppository in a dosage of up to 100 mg can be added on the same day. The total dosage of the drug should not exceed 175 mg.
For diseases of the cardiovascular system, this medicine should be used very carefully. If the course of therapy lasts for four weeks or more, then the dosage of Diclofenac injections should not exceed 100 mg.
Overdose
In case of an overdose of the drug, urgent medical attention is necessarily required, since it inhibits the activity of the nervous system, affecting the respiratory centers, and provokes respiratory depression. In addition, the introduction of a large dose may cause renal failure, necrosis of the renal tubules or their sclerosis.
From the side of the nervous system, there may be a complete loss of orientation in space, memory loss, headache, fainting, hallucinations. In addition, with an overdose, a digestive disturbance may occur. In particular, the risk of drug-induced hepatitis or internal hemorrhages increases significantly. Long-term treatment with this drug significantly exceeds the risk of a heart attack.
Contraindications
There are several absolute contraindications for Diclofenac injections, which include such as:
- individual intolerance of the constituent components;
- peptic ulcer with severe defects on the mucosa;
- violation of the process of blood formation in the bone marrow;
- internal bleeding;
- pregnancy in the third trimester;
- children under the age of fifteen.
With extreme caution, it is necessary to use the drug in case of relative contraindications, which include:
- pathology of the digestive system;
- impaired functional activity of the kidneys and liver;
- elderly age;
- increase in pressure;
- heart failure.
Taking this drug can trigger asthmatic attacks, local swelling on the mucous membranes and skin. If the patient has been prescribed surgery or dental procedures, then he must inform the attending doctor.
Before prescribing the drug to elderly patients, they must undergo a comprehensive examination.
Side effects
After the start of the use of Diclofenac, various side effects may occur on the part of various organs and systems. The very first signs of a violation from the hematopoiesis should include such as:
- sore throat;
- temperature rise;
- erosion in the oral cavity;
- depression
- bleeding.
If all these manifestations occur, you must definitely stop taking the medicine and inform the doctor about the presence of violations. With prolonged use of the drug, blood tests should be performed regularly. On the skin, reactions of excessive sensitivity to the components of the drug sometimes occur, which manifest themselves in the form of rashes and skin itching. In some cases, hives and hair loss may occur. The immune system is able to respond to the drug with such manifestations as:
- nausea and vomiting;
- headache;
- impaired consciousness;
- enlarged lymph nodes.
On the part of the liver, an increase in enzymes in the blood can be observed, and in some cases, a violation of the functioning of this organ, which manifests itself in the form of inflammation with or without jaundice.
Among the side effects from the nervous system, the following should be highlighted:
- irritability;
- fatigue;
- depression;
- feeling of fear;
- disorientation in space;
- tremor of limbs;
- cramps.
At the injection site, a local inflammatory reaction can be observed, which is accompanied by painful sensations, redness of the skin, as well as the development of infiltrate. If all these violations occur, you must immediately stop the administration of the drug.
Results of using the product
Many patients are interested in how much Diclofenac injection works, how it is absorbed and excreted from the body. Based on the instructions, the maximum concentration is observed approximately twenty minutes after administration of the drug. It is excreted by liver cells - hepatocytes, which are characterized by the fact that they bind and excrete metabolites. The duration of the drug is approximately three to six hours, it all depends on the severity of the course of the disease.
It is worth noting that this medicine in the form of an injection helps to quickly eliminate the negative symptoms, but does not affect the underlying disease. It is intended solely to relieve inflammation and pain.
Interaction with other drugs
When combined with antibiotics, the risk of toxic damage to the kidneys, liver and intestines is significantly increased. When combined with gold medications , convulsions and severe signs of digestive and respiratory systems may develop.
It is not recommended to use "Diclofenac" simultaneously with diuretics, as this leads to fluid retention in the body. This provokes the occurrence of swelling and signs of intoxication. The combination with “Aspirin” somewhat reduces the anti-inflammatory effect and increases the risk of side effects mainly from the digestive system. Besides? exacerbation of gout is possible, as well as an increased risk of developing allergies and bronchial asthma.
special instructions
Before using the medicine, it is necessary to familiarize yourself with the instructions, and also consult with a doctor regarding the dosage and frequency of administration. To avoid the occurrence of side effects, do not immediately take the maximum amount of the drug.
When prescribing "Diclofenac" to patients with diseases of the liver, kidneys and heart, it is necessary to control their condition in order to avoid the development of pathology and aggravation of well-being. Diclofenac injections and alcohol are completely incompatible, which is why it is strictly forbidden to drink alcohol during treatment. The use of alcohol during therapy can cause:
- deterioration of the liver;
- the development of complications and side effects;
- decrease in the effectiveness of the drug;
- hypertension.
Diclofenac injections and alcohol are completely incompatible, since the injection form of the drug stimulates the nervous system, and alcohol, on the contrary, inhibits it. Besides? there is an increase in congestive manifestations in the circulatory system, which leads to intoxication of the body. As a result of the combination of an anti-inflammatory agent with alcohol, dangerous neurological disorders may occur. It can also trigger the development of allergies, toxic coma and anaphylactic shock.
In cases where the drug is used, it is not recommended to drive a car, as well as to perform work that requires increased attention. This is due to the fact that the medicine can provoke fatigue, drowsiness, impaired vision, fatigue. All this can lead to very dangerous consequences. In addition, a sharp cessation of the use of the drug is not recommended, as this can provoke an increase in symptoms.
Analogues of the drug
Analogs in their main active ingredient and therapeutic effect are drugs such as Dicloberl, Voltaren, Ibuprofen. Another substitute is Movalis, although it contains another active substance.
It is worth noting that Ibuprofen is much better tolerated by pregnant women and children. The Voltaren is much softer tolerated, as it undergoes more thorough cleaning during manufacture.
Drug Reviews
Be sure to study the reviews before applying Diclofenac injections (analogues are presented above). There are a lot of positive opinions about “Diclofenac” in the form of injections, since this drug helps to quickly eliminate unpleasant sensations, when unbearable pain literally hinders movement, and a person is able to return to his usual way of life.
However, many patients note the occurrence of side effects, which can be very dangerous for the patient's health.