With the modern rhythm of life, full of various stimuli and screen radiation, our eyes are especially affected. The feeling of fatigue, burning and dryness in them is familiar to very many. In such cases, a medication available in the form of eye drops, tetrisoline hydrochloride, can be an excellent aid for relieving unpleasant symptoms.
Description of the substance
It is a clear, colorless, odorless liquid. The substance is easily soluble in water and alcohol; it has a pH of 5.0 - 6.5.
Release form
Tetrizoline hydrochloride is available in the form of:
- Eye drops.
- Nasal drops.
- Nasal spray.
Mechanism of action
The mechanism of action of tetrizoline hydrochloride on the eyes is that, under its action, alpha-adrenergic receptors are excited, resulting in a decrease in edema, elimination of burning and itching, and cessation of lacrimation.
Indications for use
Due to this mechanism of action, drops of tetrizoline hydrochloride can be used for redness and swelling of the mucous eyes of any etiology. For instance:
- Irritation of the conjunctiva of the eyes under the influence of dust, smog, any strong chemical irritants (varnishes, paints, household chemicals, medicines).
- The indications should also include inflammation of the eye mucosa of an allergic origin.
- It is acceptable to use tetrizoline hydrochloride as an adjuvant in various infectious lesions of the sclera and conjunctiva.
- In addition, the drug is able to effectively eliminate the burning sensation and sand in the eyes.
- In addition, tetrizoline hydrochloride relieves swelling and pain in the eyes.
Contraindications
The drug, although applied topically, but still has a fairly pronounced effect on the human body. Therefore, there are a number of contraindications in which the use of these eye drops is prohibited. This includes:
- The patient has an allergic reaction to any of the components of the drug. This can be both a reaction to the main active substance, and to auxiliary components.
- Since tetrizoline hydrochloride is an alpha2-adrenergic agonist (stimulates these receptors), when using the drug, its ability to narrow the vessels of the eye should be taken into account. Indeed, as a result of this, a slight increase in eye pressure can occur. And if this is not noticeable for a healthy person, then for a person suffering from glaucoma it is very noticeable and even dangerous. Therefore, the drug is prohibited for use in eye diseases, which are accompanied by an increase in eye pressure.
- Contraindications also include diseases such as keratoconjunctivitis and dystrophy of the outer shell of the eye.
- It is forbidden to use the drug for the treatment of children under three years of age.
Side effects
Like any other drug, tetrazoline hydrochloride eye drops can have a negative effect on the human body, causing a number of undesirable side reactions. Namely:
- pupil dilation
- increased pressure inside the eyeball,
- mucosal redness,
- burning sensation and discomfort.
As you can see, all these reactions are local in nature. They pass independently after the cancellation of this drug.
Nevertheless, the instructions for use indicate some systemic side effects:
- headache,
- fatigue,
- fatigue,
- sleep disturbance, insomnia,
- high blood pressure
- nausea, vomiting,
- the development of an allergic reaction in the form of a skin rash.
Use during pregnancy and during breastfeeding
The instructions indicate that, if necessary, the doctor can prescribe the drug to a pregnant woman, but the ratio of the possible benefits to the mother and the risk to the fetus should be taken into account.
A woman who is breastfeeding can use tetrisoline hydrochloride when prescribed by a doctor. However, it is worth taking into account the fact that official studies that could prove the safety of the use of the drug by nursing do not currently exist.
Dosage regimen
As a rule, the drug is instilled into the conjunctival sac of a sick eye from two to four times a day, one or two drops at a time.
If the patient wears contact lenses, they must be removed before using the drug and put on 15 minutes after instillation of the drug. The fact is that the composition of the product includes benzalkonium chloride, which is able to change the color of the lens.
The duration of the course depends on the diagnosis and can be prescribed by a doctor individually for each patient. As a rule, the course of treatment with tetrizoline hydrochloride is 7-10 days.
Analogs
In the modern pharmaceutical market, there are several analogues of tetrisoline hydrochloride. Let's consider some of them.
"Vizin"
The drug is of Russian production, is one of the most popular representatives of eye drops based on tetrizoline. It is characterized by a rapid onset of therapeutic effect. The patient notices improvement in well-being already a minute after applying the drops. As a rule, the effect lasts about 7 hours.
In addition to the dropper bottle, the drug has another form of release - disposable dropper tubes. It is very comfortable. First, the solution remains sterile. Secondly, you can take them with you.
"Montevizin"
Another drug based on tetrizoline hydrochloride for the eyes. Vizin's analogue, which is being produced by a Serbian pharmaceutical company called Hemofarm AD
The main advantage is a lower price. One tube of Vizina containing 15 ml of solution costs 290-340 rubles, and 10 ml of Montevizin costs 140-190 rubles.
The list of indications, contraindications and unwanted adverse reactions is similar in both drugs.
Reviews about the drug
If you study in detail the reviews of patients who have undergone treatment of various ophthalmic diseases with tetrisoline hydrochloride, you can see that most of them are positive.
The main plus that people give out is the rapid onset of noticeable improvement and the prolonged continuation of the therapeutic effect.
The second is the presence of several brands, so the patient always has a choice which drug to buy.
The third advantage of using these drops is the almost complete absence of any side effects. In a very small percentage of people, there was a burning and tingling sensation in the area of the eyeballs.
Pharmacy Vacation Terms
Tetrizoline hydrochloride-based eye drops are prescription drugs. This means that they cannot be found in the public domain. In order to purchase them, you should consult a doctor who, if he sees fit, will write out a prescription of a strictly defined form (form number 107-1 / y).
Before dispensing a medicine from a pharmacy organization, a pharmacist (or pharmacist) will ask you for a prescription and check that it is correct. After which drops of tetrisoline hydrochloride will be sold to the buyer.
Terms and conditions of storage
Eye drops should be stored in a dry place, protected from direct sunlight, at an air temperature of no higher than 25 degrees.
Adults should ensure that the medicine is always out of reach of young children.
An unopened vial can be stored for three years from the date of manufacture.
An opened bottle with drops must be used within 28 days, after which the drug loses its sterility and becomes unsuitable for use.
If you use the medicine "Vizin" in the form of disposable tubes, droppers, the unused contents of each of them must be disposed of immediately.
Conclusion
The drug to which this article is devoted can be an excellent helper for tired and sore eyes. Drops of tetrisoline hydrochloride is a very effective drug for the treatment of many ophthalmic diseases.
The drug is presented on pharmacy shelves in the form of several trade names of different manufacturers and price categories. This allows the patient to choose a more suitable option for him.