In the article, we consider the instructions and analogues for the Infezol preparation.
This medication is a drug in the form of a solution intended for infusion administration. The drug helps to nourish the body without the participation of the gastrointestinal tract in this process. The medication is produced in two forms - "Inezol 40", the energy value of which is 1551 kJ / l, and "Inezol 100" with an energy value of 1700 kJ / l.
The composition of "Infezol" includes the following substances:
- Amino acids. Synthesize the protein and restore the integrity of the DNA structure.
- Electrolytes. Allow to normalize the balance of fluids and salts in the body.
- Xylitol. It is a source of calories, broken down into metabolic products.
All these components in the composition provide the body with nutrients, stimulate tissue regeneration and growth, and also help maintain normal body weight.
Analogs of "Infezol" should be selected by a doctor.
Indications and Usage
"Infezol" is used in the following conditions:
- Replenishment and normalization of the balance of fluids and salts in the body.
- Stimulation of metabolic processes during the rehabilitation period after the operation.
- Increasing the body's resistance to external influences.
- Normalization of acid-base balance.
- Protein deficiency prevention.
- As a parenteral nutrition for hypoproteinemia, when the protein content in the blood plasma decreases sharply, as well as against the background of intoxication dehydration, intestinal obstruction and digestive system disorders.
- Other conditions when it is necessary to replace regular parenteral nutrition.
"Infezol" is used by intravenous drip, which allows you to use all the amino acids contained in it in the process of protein formation. Only five percent of the drug is excreted unchanged in the urine. The solution is transparent, does not have a precipitate, is packaged in sealed bottles.
The drip administration of "Infezol" should occur under the supervision of a specialist. The procedure is carried out at a speed of 1 ml of solution per 1 kilogram of patient’s body weight per hour. The introduction should begin with a minimum speed, gradually bringing to the indicated dosages.
Dosage
Dosage calculation takes into account the patient's condition, the nature of the pathological process and the amount of protein in the body. The optimal dosage is 10-20 ml per kilogram of weight.
"Infezol" is used according to the instructions in the following dosages:
- Adult patients are prescribed 0.6-1 g, that is, up to 25 ml of solution per kilogram per day.
- Children over the age of two years are prescribed up to 50 ml per kilogram of body weight.
- Treatment of catabolism is carried out by introducing 50 ml of the drug per kilogram of weight per day.
The dosage for the child is determined by the condition and nature of the problems. Children over two years of age are prescribed 10 ml per kilogram of weight, while from 6 to 14 years the dosage is 15 ml per kilogram. The duration of use is determined by the restoration of the process of oral ingestion.
Both the drug itself and the analogues of Infezol in pharmacies can be purchased.
Contraindications and adverse reactions
The following are the absolute contraindications for using the product:
- Unstable hemodynamics that pose a threat to the patient's life.
- Lack of oxygen in the body.
- Intoxication with methyl alcohol.
- Asthma of the bronchial type.
- Pulmonary edema.
- Violation in the metabolism of sorbitol and fructose.
- Traumatic brain injury.
- Severe liver damage.
It is not recommended to prescribe the drug to children who are under two years old. This is due to the lack of studies on the effect of Infezol on the children's body.
There are also a number of conditions in which the drug should be used with extreme caution:
- Disruption of amino acid metabolism.
- Hyperhydration when the water content is above normal.
- Hyperkalemia, accompanied by an increase in the content of potassium ions.
- Hyponatremia when sodium levels decrease.
- Severe heart and kidney failure.
- Acidosis. Increasing the acidity of the body.
To use "Infezol" against the background of gestation and breastfeeding is possible only if there is a risk to the woman's life.
Before starting parenteral nutrition, it is necessary to examine the patient according to the following indicators:
- Blood test for biochemistry. This analysis shows the content of potassium, sodium, calcium, chlorine and magnesium in the body and allows to identify their deficiency.
- Blood test for glucose.
Combining Infezol with other drugs is not recommended, as this can lead to unpredictable reactions of the body, as well as infection with its pathogenic microflora.
Overdose
If standard dosages of the drug are exceeded, it is possible to develop poisoning with amino acids, as well as an imbalance of electrolytes and hyperhydration.
Consider the most popular analogues of "Infezol".
The closest drugs to the effect, which can replace Infezol, are the solutions listed below in the article.
Aminosteril
Available in bottles of 250, 500 and 1000 ml. The cost of the drug is quite high - about 4 thousand rubles per bottle, depending on the volume. The drug is produced in several versions, including Aminosteril KE Nefro, Aminosteril KE, Aminosteril N-Gel. The main difference between the drug and Infezol is the adaptability of Aminosterol to liver and kidney pathologies, which is achieved by the absence of carbohydrates in the composition.
The disadvantages of this analogue of "Infezol" can be called its high cost, the inability to use in childhood, as well as difficulties with the purchase in pharmacies. Aminosteryl KE helps restore the balance of protein-energy amino acids. "Aminosteril N-Gel" is used for severe disorders in the liver, as well as against the background of circulatory disorders of the brain. The analogue of Infezol 40, Aminosteril KE Nefro, is distinguished by the absence of electrolytes. This allows you to use it against the background of kidney failure in acute or chronic forms.
Aminoplasmal E
Another analogue of Infezol provides the patient with everything necessary, restoring the balance of nitrogen and amino acids. Indications for the use of funds are the same. Aminoplasmal E is available in 500 ml vials. On average, the drug costs from 2900 rubles per bottle, depending on the percentage of the solution. The benefits of the drug are a wider range of applications, including coma, stroke, nephrosis and cachexia. For patients with hepatic insufficiency, a form of the drug called Aminoplasmal Hepa is prescribed. The disadvantages of the drug are its inaccessibility for purchase in pharmacies, as well as the lack of different volumes of vials, which makes its use inconvenient in cases where a large dosage is required.
Aminosol Neo
This is an analogue of Infezol 100. It is a combined drug for parenteral nutrition. The solution has a balanced composition of amino acids.
It is prescribed for parenteral nutrition (partial or complete with the addition of fat emulsions, carbohydrates and electrolytes), as well as for the prevention and treatment of protein and fluid loss in the absence of enteral nutrition. This may be the fault:
- severe diseases of the digestive system;
- injuries
- burns;
- sepsis;
- malignant tumors;
- preparation for surgery and surgery.
There are no analogues of "Inezol" in tablets.