To stay afloat and not get sick in the cold season and colds is the main task of many of us. This issue becomes especially relevant when it comes to children. Here you have to look for a variety of drugs, the action of which can strengthen the immune system and increase the body's resistance to disease. In this situation, many parents choose "Polyoxidonium" for the child, reviews say that after its use, children are less likely to get sick and begin to constantly go to kindergarten. It is often prescribed by immunologists, but after a thorough examination of the child.
The composition of the drug
"Polyoxidonium" for the child (reviews of some mothers pay attention to the fact that the drug should be prescribed by a specialist and only after studying the immunogram) is most often prescribed in the form of suppositories and dry powder for the preparation of the solution. Children from twelve years old can take pills.
One tablet contains 12 mg of azoximer bromide. Auxiliary components in tablets are stearic acid, lactose monohydrate and potato starch.
The lyophilisate for the manufacture of a suspension contains the active substance azoximer bromide as part of the composition. Available in a dosage of 3 mg and 6 mg. Additional ingredients are betacarotene, mannitol and povidone.
Vaginal and rectal suppositories contain azoximer bromide at a dose of 6 mg and 12 mg. The basis is cocoa bean oil, in an amount of 1.3 g per suppository. Secondary substances here are the same components as in the powder for solution preparation.
Release form and description
"Polyoxidonium" for a child (reviews of some mothers say that it is not always effective and children continue to hurt after using it in the previous mode) has the following release forms:
- tablets;
- suppositories for rectal and vaginal administration;
- powder for injection and intranasal use.
The drug in tablets is available in blisters of 10 and 20 pieces. Dragees are painted in white and yellowish color. Have a risk, chamfer and the inscription "PO". On their surface, slight inhomogeneous inclusions can be observed.
The lyophilisate for the manufacture of the solution is made in ampoules and glass vials in a dosage of 4.5 and 9 mg. Each contour cell contains five ampoules or vials. In total, there are 50 ampoules (bottles) in a cardboard box. This package is marked "for hospitals." The medicine is hygroscopic and sensitive to light.
Suppositories have a torpedo shape and are painted in a yellowish tint. When used, you can feel the unobtrusive aroma of cocoa. There are five of them in the blister. There are two blisters in the package.
Pharmacodynamics
Doctors recommend taking “Polyoxidonium” for a child (reviews say that the drug facilitates the course of the disease in case of bronchopulmonary diseases) with weak immunity, since this drug is immunostimulating and increases the child’s resistance to local and generalized infections.
The drug has a direct effect on phagocytic cells and natural killers. Promotes the formation of a large number of antibodies. With repeated immunodeficiency diseases, it restores protective functions. This effect of the drug occurs with ailments caused by injuries, various infections, autoimmune processes, burns, malignant neoplasms and a serious postoperative condition. Also, the drug is prescribed for patients using steroid hormones, chemotherapeutic agents and cytostatics.
In addition to immunomodulatory properties, Polyoxidonium is characterized by detoxification and antioxidant qualities. It relieves the body of toxins and salts of heavy metals. Suppresses oxidative reactions. Due to this effect on the body, the medicine is successfully used in the complex treatment of cancer patients. In this case, it reduces the intoxication of chemotherapy and radiation therapy, which helps to avoid the negative consequences of these procedures.
The appointment of "Polyoxidonium" in repeated immunodeficiency conditions increases the effectiveness of therapeutic treatment and shortens its duration. It increases the period of remission of certain diseases and shortens the period of use of antibiotics, bronchodilators and glucocorticosteroids.
The drug is well tolerated, mitogenic, has polyclonal activity and is endowed with antigenic qualities. It does not negatively affect the body.
Indications for use of Polyoxidonium
Reviews for children (the price of the drug varies around a thousand rubles) say that the drug increases the protective functions of the body, and the child is much less sick after using it.
For children, the drug is prescribed for bacteriovirus and fungal diseases in the acute and chronic stages. Recommended for use in severe allergies and toxic poisoning of the body. The appointment is bronchial asthma, complicated by diseases of the upper respiratory tract. Prescribe a drug for atopic dermatitis with purulent foci, dysbiosis and for faster rehabilitation of protracted diseases. It is used as a preventive measure to prevent the occurrence of influenza and SARS.
Tablets "Polyoxidonium": instructions for use
Price (reviews for children are not advised to prescribe the drug on their own, without consulting a doctor, since this is a very strong immunostimulating drug that has not been fully studied) for some mothers is quite high and therefore not everyone can afford to buy it.
Taking tablets is carried out in two ways: orally and sublingually. The pill is drunk half an hour before the main meal. For adults, the daily dose is 24 mg per day, and children of the age category from twelve years should consume no more than 12 ml per day. The medicine is prescribed up to 3 times a day.
Sublingually prescribe the drug for various diseases of the mouth and pharynx. The maximum daily dose is 24 mg, it is divided into two doses, in each of which 12 mg is absorbed. The interval between taking the drug should be at least 12 hours. Treatment lasts up to 14 days.
If diseases of the mouth are caused by infections of herpetic and fungal nature and have passed into a severe form, then the drug is recommended to take 12 mg up to three times a day. The interval between taking the pill is eight hours.
For chronic otitis media and sinusitis, take one tablet twice a day. Duration of administration is 5-10 days.
With chronic tonsillitis, you should dissolve one pill three times a day, maintaining an interval between doses of the drug, equal to eight hours. The duration of therapy is up to two weeks.
Chronic bronchopulmonary diseases are treated with a dose of 24 mg, which must be consumed in two divided doses. The course lasts up to two weeks.
For the prevention of influenza and SARS, if the patient is sick more than four times a year, the drug is used twice a day. Treatment lasts up to 15 days.
Oral administration of tablets is indicated in the treatment of upper respiratory tract. Here, for an adult, the norm is 24 mg (two tablets), for children from 12 years old - 12 mg. The course is two weeks.
Candle application method
Often recommended to the child for the prevention of colds, suppositories for rectal use of Polyoxidonium. Instructions (reviews for children are advised to enter candles with caution, since they are allowed to be used only from 6 years old, and when used at an earlier age they are divided into two parts) Before using the drug, it is recommended to consult a doctor.
The drug in this form is used once at night, but each case is individual and the duration of treatment is controlled by a specialist. The drug can be used every day, as well as every other day, two.
By dosage, the drug "Polyoxidonium" is divided into two categories:
- Candles 6 mg for children (some patients say that they are less effective than injections) are prescribed at the age of six years.
- Suppositories 12 mg are indicated for increasing immunodeficiency in adults.
If suppositories are used rectally, then before introducing them into the body, the intestines are completely empty. Intravaginally, the medication is used once at night.
According to the generally accepted scheme, suppositories, regardless of dosage, are used once a day, for three days. In the future, candles are used every other day. The course treatment includes 10-20 candles. If necessary, therapy is repeated after three to four months.
Patients with chronic immunodeficiency who have immunosuppressive treatment, oncology, as well as HIV-infected individuals after exposure should use the drug for a long time, from three months to a year. Here, more than therapeutic, but supportive therapy is indicated. In this case, suppositories are administered 1-2 times a week.
Powder Instructions
Prescribe "Polyoxidonium" in the nose of children (reviews say that it is an excellent tool for the prevention of colds and flu) for adenoids and other diseases of the oral cavity. The drug can be administered to infants parenterally and sublingually. The route of administration and dose should be selected by the attending physician.
For intramuscular and intravenous use, Polyoxidonium is prescribed to children starting at three months of age daily, every other day, or every two days, at 100-150 mcg / kg. All you need to do 5-10 procedures.
If inflammatory processes occur, the drug is recommended to be administered every other day in a dose not exceeding 100 μg / kg. The duration of treatment is 7 days.
In chronic diseases accompanied by inflammatory processes, the drug is used at 150 mcg / kg, twice every 7 days. The course is ten injections.
If there is an allergic or toxic-allergic disease in the acute form, then the medicine is used intravenously (drip) at 15 mcg / kg in combination with other antiallergic agents.
In severe allergies, the drug is administered intramuscularly at a dosage of 100 mcg / kg. The break between injections is 1-2 days, the course is 5 procedures.
To prepare a liquid for intramuscular injection, an ampoule or glass vial of 3 mg is dissolved in 1 ml of water for injection, which, if necessary, can be replaced with a 0.9% solution of sodium chloride.
For intravenous injection, an ampoule or glass vial with a volume of 3 mg is diluted in 1.5-2 ml of 0.9% sodium chloride.
Intranasal and sublingual use
It can be used not only for injection, but also intranasally, sublingually immunomodulating agent "Polyoxidonium". Drops in the nose for children (reviews say that the introduction of the drug is less effective than injection, but more gentle, since the injections are very painful), normally 150 μg / kg is used for 5-10 days, i.e. 1-3 drops alternately in the left and right nostril or under the tongue, every three hours.
Drops of “Polyoxidonium” for children (reviews say that they well prevent the occurrence of viral and infectious diseases) are administered 1-3 drops in each nostril. The procedure is repeated every 2-3 hours.
Five drops of the drug per day, which is 0.25 ml of the solution, should fall on five kilograms of weight. If the child's weight is 10 kg, then ten drops or 0.5 ml of the drug are injected. Accordingly, a weight of 15 kg should account for fifteen drops or 0.75 ml of lyophilisate, and with a body weight of 20 kg it is recommended to use twenty drops or 1 ml of the drug.
To prepare a solution, 3 mg of powder is diluted in 1 ml of distilled water. You can use ordinary boiled water to prepare the Polyoxidonium lyophilisate. One drop of the drug contains about 150 μg of azoximer bromide. Its concentration is calculated based on the body weight of the child.
The finished solution is stored in the refrigerator for a week. Before use, the pipette with the solution is heated to a temperature of + 20-25 ° C.
Contraindications and side effects
The drug does not cause side effects. Sometimes, after injection, there may be a slight pain in the area of drug administration into the muscle.
The medicine can not be used during pregnancy and during the period of breastfeeding. A ban on use is individual intolerance to the components in the composition of the product and the age of the child up to six months.
Special care should be taken when using the drug in patients with acute renal failure and in children under 6 months of age.
Special instructions
He advises to prepare “Polyoxidonium” powder with a 25% procaine solution in case of muscle pain after injection, the children are advised to inject this drug into the body strictly according to the doctor’s instructions, but provided that the patient does not have an allergic reaction to procaine.
With intravenous injection, the drug is not diluted in protein-containing infusion solutions.
Cost
"Polyoxidonium" is sold only in pharmacies and sold only on prescription. The price, depending on the form of release of the drug, may vary. So, the powder for the preparation of a 3 mg solution costs about 650 rubles for five ampoules, and for 6 mg of the drug you will have to pay about 1050 rubles. The price of vaginal and rectal suppositories with a dosage of 6 mg is about 800 rubles, and for candles 12 mg will have to pay 950 rubles. The cost of packing ten tablets is 750 rubles.
Reviews
Often prescribed for protracted colds and serious diseases "Polyoxidonium" for children, doctors say that this is an indispensable tool in the treatment of a number of infectious diseases. The drug does not cause side effects and is easily tolerated by patients. The treatment regimen for each patient is selected individually.
Candles "Polyoxidonium" for children under one year of age (reviews indicate its positive effect on the body and note a reduction in the period of the disease when taking this drug) are advised to be administered with caution.
Many parents claim that the drug increases immunity, reduces the duration of the disease. It is noted that injections are most effective, although they are very painful and not all children are able to withstand them. They pay attention to the fact that this is a strong drug and should be prescribed by an immunologist after studying the immunogram. Parents advise not to rush to buy it and recommend taking an analysis of sensitivity to the drug.
Negative opinions about the drug claim that it does not have a positive effect on the body and is a placebo. Its high cost and lack of research are noted. They say that it can be dangerous for the child’s immunity and interferes with the formation of natural protective functions.