The main purpose of the drug "Esperal" is the treatment of alcoholism. As the recall confirms, “Esperal” with regular intake leads to the formation of persistent alcohol rejection. Structural analogues are the means “Teturam”, “Disulfiram”, “Torpedo”, “Antabus”. Available in the form of tablets for internal use, subcutaneous implantation and in the form of a gel.
Pharmacological properties
The active component of disulfiram promotes the inhibition of acetaldehydrooxidase, a substance involved in the neutralization and breakdown of ethanol in the blood. With partial alcohol oxidation, acetaldehyde accumulates in the body, resulting in toxic poisoning. General intoxication leads to nausea, general weakness, vomiting, tachycardia, a feeling of lack of air, lethargy, drowsiness, or excessive agitation. Similar effects contribute to the formation of alcohol rejection.
As the review indicates, “Esperal” is used at the stage of dependence, in which the patient is no longer able to control the volume of alcohol consumed. The maximum effect is observed 12 hours after ingestion. The drug "Esperal", the effect of which continues for another two weeks after the completion of the administration, can act on some patients with lightning speed, causing toxic hepatitis.
Indications and method of use
The drug is prescribed to prevent relapse during the treatment of alcohol dependence, for the detoxification of nickel poisoning. Tablets are taken in a volume of 0.5 grams once a day, it is recommended to do this during breakfast. After a 10-day use, an alcohol test is performed, after which the issue of increasing the dosage of the drug is decided. The tool must be used in a daily maintenance volume of 0.2 g for 1-3 years.
The Esperal medication is not administered intravenously; implantation tablets are implanted into muscle tissue. Usually, the product is implanted in the upper part of the buttock or iliac region to a depth of 4 cm. The gel also acts and implanted.
Contraindications
It is forbidden to use the medicine for hypersensitivity to components, renal failure, liver diseases. The drug is not prescribed for severe ailments of the cardiac and vascular system, epilepsy, diabetes. You can not use the medication during pregnancy and lactation.
Side effect, price
As evidenced by the review, “Esperal” with internal use can cause a metallic taste in the mouth, allergies, polyneuritis of the extremities, psychosis, headache. Sometimes after taking the medicine, a decrease in memory, confusion, optic neuritis, gastritis can be observed. In rare situations, asthenia, hepatitis, and thrombosis of the vessels of the brain of the head develop. With the simultaneous administration of the drug with oral anticoagulants, the likelihood of developing bleeding increases. According to the recall, Esperal can be purchased at a price of 915 rubles.