Azitrox is one of the most effective and low-toxic drugs that are used to treat infectious pathologies. Most often, it is prescribed by therapists or otolaryngologists. For moderate diseases, a three-day course of therapy is enough. This medicine is successfully used in the field of urology and gynecology in cases of infection with chlamydia of the organs of the genitourinary sphere. Short courses of antibiotic therapy are an undoubted advantage of this medicine over other categories of antibiotics.
But in order to be guaranteed to be cured of the disease, it is required to strictly observe all recommendations for use. Next, we will examine in detail the instructions for use of this medication, find out how to use this drug for the treatment of children and adult patients, and, in addition, find out in what form of release the medication is presented.
Basic information about the medication
In the list of the most popular drugs for the treatment of bacterial infections, this medicine deservedly occupies a leading position. This antibiotic is practically non-toxic, it needs to be taken for only three days, and, in addition, it can be used for children. Instructions for use with Azitrox contain such information.
In this case, the symptoms disappear on the second day. Subject to compliance with all medical prescriptions, the disease goes away without any complications.
The composition of the drug
According to the instructions for use with Azitrox, the active ingredient is the substance azithromycin, which is the first semi-synthetic antibiotic azalide from the macrolide group. The medicine received back in 1980, thanks to a wide range of its antimicrobial efficacy and low toxicity, very quickly gained the recognition of doctors and the trust of patients.
Mechanism of action
This drug acts on pathogenic microorganisms by the bacteriostatic method, that is, it stops the reproduction and development of the pathogen by inhibiting the synthesis of protein, which is necessary for its growth. With an increase in dosage, a bactericidal effect is observed, and the cell, in turn, dies. Among pathogenic bacteria, the following organisms are most sensitive to the main component of the drug azithromycin:
- Gram-positive species of streptococci along with Staphylococcus aureus, which is one of the main causative agents of persistent nosocomial infections.
- Gram-negative neysserii, gardnerella and legionella.
- Anaerobic peptostreptococci and clostridia.
- Atypical microscopic bacteria along with mycoplasmas, chlamydia, ureaplasma and pale treponema.
Release form
The manufacturer of this drug is the largest Russian company called Pharmstandard. This pharmaceutical organization produces several forms of this antibiotic at once:
- The drug is in tablets (capsules) of 500 milligrams, which in addition to the active substance also contains anhydrous lactose along with sodium lauryl sulfate, magnesium stearate and corn starch. In accordance with the instructions for use with Azitrox 500 mg, medical gelatin with titanium dioxide is used for the shell. Pills are packed in blisters and cardboard packs.
- Also, the medication is produced with a dosage of 250 milligrams with the same auxiliary components. The number of tablets in the box is six.
- In addition to tablets, a powder is also produced for the independent manufacture of a suspension. Instructions for use with Azitrox indicate that this release form is offered immediately in two versions of the concentration of the active component: 100 and 200 milligrams per 5 milliliters. Powder is sold in bottles with a cap that protects the child from accidental use of the medicine. The set also includes a measuring spoon and a graduated syringe-dropper.
The last dosage form according to the instructions should be diluted with water before first use and subsequently stored in the cold. Instructions for use with "Azitroks" 200 and 100 mg in suspension form confirms this.
Indications for use of the drug
This antibiotic is used to treat various pathologies that are caused by microflora sensitive to azithromycin. By acting bacteriostatically, it makes it possible to get rid of the following diseases in the shortest possible time:
- The presence of atypical and bacterial forms of pneumonia.
- The development of bronchitis, scarlet fever and all types of sinusitis.
- The appearance of tonsillitis and inflammation of the middle ear.
- The occurrence of urogenital infections.
- The presence of bacterial lesions of the skin, and, in addition, subcutaneous tissue and muscle tissue.
- The presence of borreliosis.
As part of a comprehensive drug treatment, Azitrox is prescribed to eradicate the causative bacteria of the stomach ulcer called Helicobacter.
Contraindications
What else does the application instruction for Azitrox tell us? This drug has a low level of toxicity, and therefore there are very few restrictions on its use. It is forbidden to prescribe this antibiotic to those people who suffer from severe liver and kidney failure, and, in addition, hypersensitivity to the macrolide group and generally to azithromycin in general.
During pregnancy
Use the drug during pregnancy also should not be, since its active component can pass through the placental barrier. There is no reliable information about the teratogenic effect on the fetus, but it is recommended to refrain from treatment with this drug.
According to the instructions for use, Azitrox tablets are not prescribed for children who have not reached the age of twelve years. For them, this medicine is made in the form of a suspension containing a smaller amount of the active ingredient, in addition, this form of release is more convenient to use for children.
Dosage and administration regimens for the treatment of adults and children from twelve years old
Instructions for use with Azitrox must be strictly observed. The bioavailability of the drug is approximately forty percent, and the presence of food in the digestive system significantly slows down the absorption process. Therefore, tablets must be taken on an empty stomach and a pause of one hour before meals or two after it should be maintained. This drug is washed down with clean water. The medicine is convenient in that only one use per day is sufficient against the background of any nature and severity of the disease. An antibiotic can accumulate in the body and finally comes out only a week after the completion of the course.
This is stated in the instructions for use with Azitrox. For adults and children who have reached the age of twelve, in the presence of a bacterial lesion of the skin and respiratory system, a preparation is prescribed in a dosage of 500 milligrams. You need to take this medicine in just one capsule every twenty-four hours for three days. Symptoms usually disappear on the second day, but the course must still be completed in order to avoid superinfection or complications. With SARS, this drug is taken for about three weeks.
Instructions for use with "Azitroks" also reports that the treatment of urogenital uncomplicated infections of gonorrheal etiology consists in a single use of 1 gram of antibiotic. As part of the eradication of Helicobacter, which is the cause of stomach and intestinal ulcers, you need to take 1 gram of the drug per day for four days. Therapy should be comprehensive, that is, it is required to use several medications of various groups at once.
Instructions for use "Azitroks" for children
For the treatment of children from six months to twelve years old, a powdered dosage form of the drug is used, which must be diluted with water before use. For children, the medication is prescribed in a dose, which is calculated by body weight, namely, they take 10 milligrams of the drug per kilogram of weight.
Instructions for use with the Azitrox suspension 200 and 100 mg are simple and straightforward.
The treatment regimen can be three days, as happens in adult patients, or treatment begins with a single daily dose, followed by a half reduction (that is, 10 milligrams per kilogram are taken on the first day, and 5 on the remaining four days).
Side effect
Macrolides, as a rule, are characterized by a fairly low level of toxicity, so they can be used even in the field of pediatrics. But in rare cases, the appearance of adverse reactions from the activity of internal systems and organs is likely.
As indicated by the instructions for use with Azitrox, in a suspension for children and in capsules, against the background of their administration, nausea, vomiting, flatulence, epigastric pain, upset stools, increased activity of liver enzymes are possible, and, in addition, an allergy in the form of skin rashes.
Exceeding the recommended dosage leads to an increase in the severity of adverse reactions. There is no specific antidote, therefore, an overdose is treated symptomatically by washing the stomach and taking activated charcoal.
Instructions for use with Azitrox capsules and suspensions should be strictly observed.
Now we will move on to familiarize ourselves with consumer reviews and find out what people write about this drug and what they think about its effectiveness.
Reviews about the drug
According to reviews, this drug is very effective in treating various bacterial infections. All patients unanimously claim that Azitrox has a high level of bacteriostatic effect and talk about successful treatment for severe sinusitis, purulent sore throat, skin diseases of an infectious nature, urogenital inflammation and so on.
Another significant advantage of this drug over other antibiotics, according to people, is a short course of its use along with a convenient treatment regimen. This drug is taken only once a day, and the maximum duration of treatment cannot exceed five days. There are no claims to dosage forms, whether tablets or suspensions, as it is very easy to take them. The symptomatology of the disease, according to reviews, disappears on the second day of treatment.
This drug is also praised as part of its use for treating children. Parents of babies note the high effectiveness of the Azitrox medication and report an almost complete absence of side effects, even in infants.
In addition, the reviews note the effectiveness of this drug in the treatment of diseases such as tonsillitis, urogenital infections and sinusitis. It is emphasized that in these cases, Azitroks helps in a short time. People also note the low cost of this drug, which is an additional advantage and is usually only about one hundred rubles.
It is also worth mentioning that only some patients complain of adverse reactions. True, such cases are single, they are usually associated with reduced immunity or with non-compliance with recommendations regarding taking the medicine strictly on an empty stomach.
The main mistake of most patients is also the cancellation of the drug at the time of the disappearance of the main symptoms of the disease, which, as a rule, disappear on the second day. But to complete the course of therapy earlier than three days is unacceptable. In addition, do not forget that it is impossible to prescribe antibiotics for your treatment without consulting a doctor in any case.
Conclusion
Thus, the drug "Azitrox" today is a very effective antibiotic, the effectiveness of which is confirmed by many patients who happened to take it for the treatment of various infectious diseases. And its additional advantages are low toxicity and a short course of administration.