Quite often, if necessary, prescribe a drug on ketorolac, doctors recommend the patient to stop at "Ketanova". The drug is available in the form of tablets and injectable solution. Proper use is described in the instructions for use. Reviews about "Ketanov" indicate that the drug has a pronounced effect and quickly relieves soreness.
general information
The product belongs to the class of anti-inflammatory non-hormonal, has a pronounced analgesic effect. In general, analgesic efficacy is comparable to morphine, but the composition of the described drug is such that it is not addictive. In the instructions for use of "Ketanov" intramuscular injections and tablets are recommended for oral use in case of pain of a strong level and moderate.
In pharmacies, the drug is presented at a price of 50 rubles or more. Usually it is prescribed for a short course and at a relatively low dosage, so this medication was available to the general public. This has become one of the reasons for its spread. The second aspect explaining the demand and popularity is the effectiveness, confirmed by numerous reviews of Ketanov. The instructions for use for injections and tablets describe the rules that must be followed in order for the drug course to be effective. It is allowed to apply the composition strictly under the supervision of a doctor. Negative feedback about the drug is mainly left by people who used it at their discretion, without consulting a doctor.
When will it help?
According to the instructions for use, "Ketanov" (injections and tablets) is indicated for pain. It is wise to prescribe the drug if the syndrome is assessed as moderate or severe. "Ketanov" will help if the pain is associated with injuries, operations and birth of a child. The drug is taken to relieve toothache and soreness caused by cancer. The drug is effective for mya, neurological and arthralgia. The clinical practice of using Ketanov by patients suffering from sprains, radiculitis and dislocation is quite widespread. The use of a medication helps to alleviate the condition of people suffering from pain of rheumatic origin.
Currently, the described tool is presented in pharmacies in the form for injective and oral administration. If necessary, for example, external application, you cannot buy Ketanov gel. The instructions for use indicate that the main component is ketorolac. It created several gels and ointments for external use, it is on them that you will have to stop. This also applies to candles and other forms of release of pharmaceutical products: "Ketanov" exists only in the form of tablets and a solution for injections.
How to replace?
If it is impossible to purchase a drug prescribed by a specialist, the choice of alternative must be agreed with the attending doctor. As a rule, an agent is prescribed based on the same active component - ketorolac. In the instructions for use of Ketanov analogues, this substance is necessarily mentioned in the composition section in the first place. The most popular drugs:
The price of these drugs, their indications, contraindications and side effects are generally similar, since all options are made on the same active connection. Not only instructions for use: reviews about the analogues of "Ketanov" are also approximately close to each other. A somewhat more expensive alternative to these medicines is the Ketofril preparation, the price of which varies within 100 rubles per package. Approximately half the price will cost an analogue of Ketanov injections, the instructions for use of which also indicate ketorolac as the main substance - Ketokam.
It is unacceptable to replace the drug prescribed by a doctor without the consent of the doctor. The specialist should know about all the drugs used by the patient. Unauthorized adjustment of the drug program can cause the ineffectiveness of therapeutic measures, the appearance of side effects, including severe ones.
Technical details
The instructions for use for "Ketanov" (injections and tablets) indicate that the medication belongs to the group of anti-inflammatory non-steroidal. The drug effectively suppresses the activity of inflammatory foci due to inhibition of inflammatory mediators. Belongs to the class of non-hormonal, which explains a number of nuances of its application.
Coated tablets containing ketorolac and some additional components, due to which the product is stored for a long time and is better absorbed when passing through the gastrointestinal tract, are on sale. Another form of release is Ketanov in ampoules. The instructions for use indicate the rules for the administration of the substance: it can be intended for administration into muscle tissue or into a vein. All restrictions and rules that the manufacturer indicates in the accompanying documentation must be observed very clearly during treatment.
It is impossible!
In accordance with the instructions for use, "Ketanov" (intramuscularly or orally) can not be taken if the patient has an increased sensitivity to the main component of the drug or additional substances present in its composition. And also with immunity and allergic reactions to any of its compounds.
You can not use the remedy for asthma, a tendency to relapse of polyps in the nose and intolerance to the pyrazolone series and ASA. "Ketanov" is prohibited in case of hypovolemia, ulcers and erosion in the gastrointestinal tract, a decreased level of blood coagulability, with bleeding or an increased risk of their occurrence, with insufficient kidney function in acute form.
"Ketanov" is prohibited in liver failure. An anti-inflammatory agent is not used at the time of birth, while breastfeeding. It was not revealed how “Ketanov” is effective and safe for people under 16 years of age, therefore it is not used for this category of patients.
In the instructions for use of Ketanov, the manufacturer indicates that it is allowed to use the drug only if it is possible to constantly monitor the patient’s condition, if hypersensitivity to any non-hormonal anti-inflammatory is detected, if the patient is asthmatic, smokes, has an addiction to alcohol, suffers from cholecystitis.
“Ketanov” is used very carefully after operations, in case of chronic heart failure, a tendency to edema, high blood pressure, creatinine clearance of less than 50 mg / l.
It is allowed to use the described tool only if possible on a regular basis to monitor the body's vital signs in patients with detected acute hepatitis, blood poisoning, cholestasis and SLE.
Extremely carefully combine the medication and other NSAIDs. Particularly attentive should be to pregnant women and the elderly.
How to use?
All rules by the manufacturer are indicated in the instructions for use accompanying "Ketanov". The tool can be used orally (in the form of tablets) and for injections into a vein / muscle (the instructions specify what the solution is suitable for). When choosing an injective form, the duration of the administration procedure is from 15 seconds or more. When using tablets by persons whose age is 16–64 years and weight is more than 50 kg, it is necessary to adhere to the following regimen of administration:
- the first dose is 20 mg;
- continuation of the course - four times a day, 10 mg;
- the maximum daily dose is 40 mg.
In case of kidney failure or weight less than 50 kg, adult patients are prescribed 10 mg of the drug for first use and 10 mg four times a day as a continuation of the course.
Orally allowed to use no more than 40 mg of the drug per day.
Injection form: rules of use
Instructions for use "Ketanov" is recommended for introduction into muscle tissue for patients of the age group 16–64 years old with a weight of more than 50 kg. In one procedure, you can enter up to 60 mg of ketorolac (take the tablets taken by the patient). The classic format is injections of 30 mg of the substance with six-hour intervals between them. The substance can be injected into a vein up to 15 times 30 mg in five days.
With a weight of less than 50 kg or with insufficient functioning of the kidneys in a chronic form, persons over 16 years of age are shown a single administration of no more than 30 mg, but twice as small doses are most often practiced, the amount of which should not exceed 20 in five days of the course. with six hour intervals. Five days should be no more than 20 doses.
At the age of 16–64 years and weighing more than 50 kg, the maximum dose of “Ketanov” per day in the form for injection is 90 mg. With less weight or chronic renal failure, in old age the volume is reduced to 60 mg. The duration of the use of the medication is no more than five days.
How it works?
The mechanism of influence of the components of the medication is described in detail by the manufacturer in the instructions for use accompanying “Ketanov”. It is indicated here that the substance moderately reduces fever, alleviates pain and relieves inflammatory processes. Ketorolac does not selectively deactivate COX of the first and second types, under the influence of which inflammatory mediators are formed, provoking a febrile state, pain. "Ketanov" is a fairly strong analgesic in effectiveness close to morphine. It is more effective than most of the non-hormonal type of anti-inflammatory drugs known to mankind.
With the introduction of the drug into a vein or muscle tissue, the analgesic effect can be felt on average after half an hour. When using tablets, the waiting time is doubled. The most pronounced result of administration when using injections is observed 1-2 hours after the injection, in tablet form, 2-3 hours after the agent enters the esophagus.
Negative consequences
The instructions for use and reviews of Ketanov testify to the possibility of such. Injections and pills can cause disruption of the gastrointestinal tract. Patients complain of pain in the stomach, stool disorders, nausea and vomiting, increased gas formation and poor appetite. Perhaps the development of erosion or ulcers with prolonged use of the product and non-compliance with recommendations for its use.
Occasionally, cases of kidney failure and impurities in urine of various components (blood, nitrogen) have been observed. Possible nephritis, swelling, changes in the volume and frequency of discharge.
In some patients, “Ketanov” provokes tinnitus and hearing impairment, blurred perception of the visual picture, bronchospasm, runny nose, pulmonary edema, shortness of breath. Possible headache or craving for sleep. Some are dizzy. Cases of aseptic meningitis, anxiety and mood swings, hallucinations and depression, fainting, and psychosis have been reported. The drug can cause increased pressure, leukopenia, anemia, bleeding, rash, dermatitis, urticaria, erythema, necrolysis. There is a risk of an allergic response and pain at the injection site. In some patients, during the therapeutic course, the work of the sweat glands is activated, it can be in a fever.
Too much!
With a single use of too large a dose of the drug, the patient complains of abdominal pain, he is sick and vomits, erosion ulceration sections form in the digestive tract. Renal functionality is impaired, acidosis is possible. The treatment is symptomatic, under the supervision of a doctor, drugs are selected to maintain the most important functions of the body. Tests have shown that dialysis shows no result.
Special conditions
Before starting the Ketanova course, it is necessary to clarify whether in the past the patient had an allergic reaction to any non-hormonal anti-inflammatory, including those based on ketorolac. The increased likelihood of an allergic response forces the first administration to constantly monitor the patient's condition in order to provide urgent care in a timely manner. With hypovolemia, the use of the composition is associated with a high risk of a negative response of the body, expressed in toxic reactions to the kidneys. If “Ketanov” alone does not show the necessary effect due to the severity of the patient’s condition or other individual characteristics, you can combine the drug with narcotic drugs for pain relief.
If it is necessary to maintain anesthesia, it is not recommended to use Ketanov for sedation.
The combination of the described composition and other non-hormonal anti-inflammatory drugs can cause fluid retention and disruption of the heart, increased pressure. On average, the effect on platelet aggregation takes place 1-2 days after the last dose. You can not simultaneously use "Ketanov" and paracetamol for more than five consecutive days. For problems of blood coagulation, “Ketanov” is allowed to be used only if it is possible to regularly check the blood platelet count. This is especially important after recently undergoing surgery, when it is necessary to control hemostasis.
Application Nuances
The manufacturer indicates that the likelihood of complications, side effects increases if you use "Ketanov" more than five days. This is sometimes practiced for chronic pain, but it is necessary to take into account all the risks and weigh the benefits of such practice before starting treatment. The likelihood of side effects is also increased when the dosage of Ketanov in tablets is exceeded (the recommended dose is up to 40 mg per day).
To slightly reduce the likelihood of gastropathy against the background of the ingestion of ketorolac, the drug can be combined with antacids and omeprazole.
The use of "Ketanov" requires special accuracy in everyday life. If possible, control over equipment (machines and apparatuses requiring an increased reaction rate and accuracy of actions) should be abandoned. Against the background of the use of ketorolac, it is possible to slow down psychomotor reactions, which creates an increased level of danger in a number of forms of activity.
Mutual influence
If you simultaneously use "Ketanov" and paracetamol, the mutual influence of medicines will have a strong toxic effect on the kidneys. This is evidenced not only by the instructions for use. Reviews of "Ketanov" in injections and tablets also confirm the fact of an increased likelihood of side effects. With the simultaneous use of corticotropin, ethanol, non-hormonal and hormonal anti-inflammatory, calcium preparations, the likelihood of ulcers, erosion, and bleeding sites in the gastrointestinal tract increases.
The combination with blood thinners made on coumarin, indandion, heparin, as well as some antibiotics, thrombolytics can cause bleeding. Diuretics and drugs to lower blood pressure while entering the body with Ketanov show less effectiveness.
The combination of Ketanov and methotrexate increases the toxic effects on the liver and kidneys. At the same time, these drugs can only be used if methotrexate is prescribed in the minimum dosage and it is possible to regularly monitor the concentration of this compound in the blood serum.
Use in combination with toxic drugs for the kidneys, including gold preparations, is associated with a high risk for this organ. Compounds that inhibit tubular secretion reduce the clearance of ketorolac, as a result, the plasma concentration increases. The toxic effect on the circulatory system increases when combined with myelotoxic compounds.
Are there any options?
The appointment of "Ketanov" often becomes a cause for fear for the patient - many are afraid of injections, phobias of syringes are frequent, and the injection procedure itself is rather painful. Against this background, patients are interested in whether it is possible to use the drug in another form (for example, if the Ketanov ointment). Instructions for use exist only for two forms of the drug: for oral use and injective administration. "Ketanov" for external use is not available.
Others are wondering if the candles are "Ketanov." Instructions for use for such a drug, as well as himself, do not exist. There are candles on ketorolac, they are produced under the name "Ketonal". «» , . .