The article will discuss how to use sodium thiosulfate in gynecology.
Pharmacology is an immense science, which sometimes presents people with very interesting surprises. Medicines that were previously developed for the treatment of narrow pathologies are now useful in a wide variety of fields. This can be said, for example, with a pharmaceutical such as sodium thiosulfate. Initially, this medicine was developed to treat all kinds of poisoning and allergic ailments. But today, sodium thiosulfate in gynecology is used as part of the complex treatment of infertility and other pathological processes.
About the drug
Sodium thiosulfate in medicine is a comprehensive therapeutic agent that has a wide spectrum of action and produces an antiparasitic, anti-inflammatory, desensitizing and detoxifying effect.
Recently, doctors have noted that sodium thiosulfate in gynecology (enemas, injections, electrophoresis) is used quite often. As for microclysters with this solution, they are used as a therapeutic agent.
Release format
This drug is produced in the form of crystals, which are distinguished by a transparent color. They do not have a smell. It is worth noting that these crystals have a somewhat salty and at the same time bitter taste. They can dissolve very well in water. The prepared solution is usually taken orally or it can also be used externally. Sometimes this medicine is prescribed for the intravenous route of administration. Thiosulfate can be used as an anti-inflammatory, antiparasitic and detoxification drug.
Microclysters with sodium thiosulfate are popular in gynecology.
It is worth noting that the spectrum of exposure for this medication is very wide. For example, with its help tuberculosis, scabies, allergies, neuralgia, arthritis, eczema and heavy metal poisoning are successfully treated. But in particular, the actively presented remedy is used today in gynecology.
Reviews of sodium thiosulfate are mostly positive.
The pharmaceutical composition of the solution
The composition of the presented product includes an active active ingredient, which is called sodium thiosulfate. In addition, excipients in the form of water for injection, sodium bicarbonate, disodium salt and ethylenediaminetetraacetic acid are also present in the solution.
Mechanism of action
Sodium thiosulfate is endowed with a mass of various therapeutic effects and has a complex mechanism of action. Here are some of its features.
- The detoxification property of the drug lies in the fact that it binds to various toxic substances, namely heavy metals, cyanides, halogens, iodine, benzene, hydrocyanic acid and phenols. After this, the drug neutralizes them and forms non-toxic compounds. A very positive effect is detected against the background of poisoning by arsenic, lead and mercury.
- In the presence of a parasitic disease such as scabies, this drug can destroy the scabies mite with its eggs due to decomposition into sulfur dioxide and sulfur, thus damaging the body of parasites.
- In the presence of allergic reactions and arthritis that differ in immune origin, thiosulfate is used as a desensitizing and anti-inflammatory drug. Until now, the mechanism of this effect of the drug has not been fully studied, although its anti-inflammatory activity has been fully proven.
As can be noted, the listed effects from this drug are not directly related to the treatment of gynecological pathology. It is thanks to this that the tool is used in gynecological practice as part of complex therapy.
Doctor's prescription
Doctors often use sodium thiosulfate in gynecology. For example, gynecologists prescribe sodium thiosulfate for the treatment of diseases such as infertility, which is caused by the patient's lack of ovulation, ovarian cyst, as well as with endometriosis and tuberculosis.
In the event that a woman has completely no ovulation, then a gynecologist diagnoses infertility. True, modern medicines along with alternative methods of treatment (for example, hirudotherapy) make it possible to successfully cure infertility. In addition to the use of sodium thiosulfate in gynecology intravenously, as part of the treatment of infertility, physiotherapeutic procedures in the form of plasmapheresis and electrophoresis of nicotinic acid are additionally prescribed. Additionally, patients undergo treatment with Actovegin. But since it can provoke some allergic reactions, the use of sodium thiosulfate makes it possible to reduce the risks of such reactions in women during treatment.
For the treatment of ovarian cysts, thiosulfate is prescribed in combination therapy in combination with medicines in the form of "Dimexide" and "Diclofenac". In parallel, Vishnevsky ointment is used. Sodium thiosulfate is usually administered intravenously in an amount of 10 milliliters in combination with other drugs, for example, with Lidase and vitamin E for the treatment of tuberculosis in gynecology.
A very serious problem is the therapy of endometriosis, which is treated mainly with hormonal drugs. However, there is a small number of non-hormonal drugs, which include sodium thiosulfate. With endometriosis, it is used as an anti-inflammatory and absorbable agent.
Electrophoresis is carried out with sodium thiosulfate in gynecology in the form of microclysters of a one percent solution in the amount of 50 milliliters.
The course of therapy in this case is twenty procedures. The electrophoresis technique is used as a priority in cases where it is not possible to administer the drug intravenously due to poor veins or intolerance to the drug itself. However, such intolerance is quite rare. Next, find out what indications are available for the use of this tool.
Sodium thiosulfate and indications
Outside the sphere of treatment of female diseases, the presented tool also found its application. The main indications for the use of the drug are the following ailments:
- Poisoning by various chemical compounds. The tool acts as an antidote to a wide range of different substances.
- For the treatment of scabies. It is worth noting that sodium thiosulfate is very effective in this parasitic disease despite the fact that most antiparasitic medicines do not have the necessary effect on the scabies mite.
- In the presence of allergic reactions of varying severity. Against this background, the drug is used not only as a treatment for allergies, but also for its prevention.
- With arthritis of various etiologies, for example, the anti-inflammatory and decongestant properties of the drug help with the symptomatic treatment of inflammatory diseases in the joints.
- For the treatment of neuralgia of inflammatory origin. The fact is that many neurological pathologies are directly related to inflammatory processes in the region of the peripheral nerve. In this case, the tool is used as a symptomatic drug.
The above indications for the use of the drug are wide and non-specific. In addition to them, methods of using sodium thiosulfate intravenously in gynecology are very common.
Application in gynecology
It is difficult to imagine a gynecological disease, in the presence of which thiosulfate could be used as monotherapy. But as part of complex therapy, this medicine is used quite widely. The main indications in the field of gynecology include:
- As part of the comprehensive treatment of anovulation. This condition leads to infertility, since a full egg cannot mature in the ovary. For therapy, electrophoresis and phonophoresis using nicotinic acid and Actovegin are used. But these drugs can sometimes cause allergic reactions. To prevent this complication, therapy is supplemented with sodium thiosulfate.
- Ovarian cysts are a congenital or acquired pathology that occurs in a large number of women. They can lead to infertility and apoplexy. The anti-inflammatory pathogenetic effect is exerted by the combination of the drug with non-steroidal anti-inflammatory drugs. The described component in this case is administered intravenously.
- A serious condition is tuberculosis of the organs of the female reproductive system. Infectious processes can affect absolutely any reproductive organ. In addition to specific antimicrobial therapy, patients are prescribed an anti-inflammatory treatment complex in the form of vitamin E, sodium thiosulfate and Lidase. The last drug prevents the development of adhesions in the abdominal region.
- Endometriosis is associated with the growth of cells from the inner layer of the walls of the uterus in other anatomical areas. Since this pathology is considered hormone-dependent, the basic part of the treatment consists mainly of all kinds of hormonal agents. But in order to eliminate the symptoms of inflammation, sodium thiosulfate is used. The best effect is achieved using microclysters.
The listed indications reflect the majority of pathological conditions, against which the use of this drug is most effective. In addition to the indications, the instructions for the use of sodium thiosulfate in gynecology also contain contraindications along with side effects of the drug, which also must be taken apart.
Contraindications
The drug in question should in no case be used if there is a history of intolerance to this drug. Allergic reactions can occur absolutely on any component introduced into the human body, even, paradoxically, as an anti-allergic agent. In the presence of the first signs of allergic reactions, it is imperative to abandon the subsequent use of thiosulfate in any of its dosage forms.
Of particular concern is the use of the drug in the presence of pregnancy in women. A qualitative study on the effects of this medication on gestation has not been conducted. Instructions for use does not recommend the use of this tool in the presence of pregnancy. In case of indications during pregnancy for the use of the drug in question, you should use analogues or discuss the possibility of treatment with sodium thiosulfate with an obstetrician.
Is it always safe to use sodium thiosulfate in gynecology?
Side effects
The only side effect noted in the instructions for the medication in question is an allergic reaction. This occurs if a person has an individual intolerance to this remedy.
Complications from therapy are post-injection abscesses along with infiltrates with improper intravenous administration of the drug. It is in this connection that the injection should be trusted exclusively to medical personnel. It is forbidden to use sodium thiosulfate intravenously at home.
According to reviews, in gynecology this drug is indispensable, however, it must be used carefully.
Instruction manual
There are several options for the use of thiosulfate in medical practice. Each of them has its own indications and instructions for use.
- The use of the solution. The medicine in a sixty percent solution is used externally for the treatment of manifestations of scabies. The solution is rubbed into the skin of the entire surface of the body, excluding the head. After drying, the skin is moistened with hydrochloric acid in a concentration of six percent solution.
- Carrying out microclysters. With manifestations of endometriosis of the female genital organs, vaginal microclysters with thiosulfate are used. They are injected into the vagina from one to two times a day, depending on medical recommendations.
- Performing injections. An injectable form of the drug is often used. An intravenous drug is administered only once a day, which is done over a wide range of volumes, depending on the severity of the disease. Prophylactic dosages of the drug are ten times less than those used in the presence of severe allergies.
Intravenous injections are performed by nurses in medical institutions. Next, we find out that women and gynecologists report this remedy in reviews.
Reviews of women and doctors
According to reviews, sodium thiosulfate in gynecology is well tolerated intravenously. Rarely causes side effects.
Doctors are prohibited from using the product by patients during pregnancy and lactation. Its use during this period can provoke the appearance of allergic reactions in women. Doctors' reviews of sodium thiosulfate in gynecology intravenously confirm this.
In this case, it is necessary to assess the potential benefits of using this medication for the patient along with the severity of the allergy. As doctors write, if the allergy is very strong, then the drug must be completely canceled.
This remedy is also praised by patients who note that this drug is gaining confidence due to the fact that it is able to prevent the occurrence of an allergic reaction in the course of complex therapy of certain gynecological pathologies. The universality of its use (powder, ampoules for injections, and so on) allows you to select the most optimal methods of application in absolutely every specific case, namely intravenously, in the form of microclysters or as part of a physiotherapeutic procedure, for example, electrophoresis.
In particular, patients like the fact that this medicine has no side effects. Largely because of this, the drug in question is most often used to treat serious gynecological pathologies.
Gynecologists also use the drug presented with special confidence, because its use together with other drugs reduces the risks of side effects from them. In many medical guides, sodium thiosulfate is recommended as an antidote (i.e., an antidote). For example, doctors note that this remedy successfully helps with poisoning by mercury vapor, lead, and substances that contain arsenic.
According to doctors, he can even cope with cyanide poisoning, for this the medicine is administered intravenously. Also, this medicine is often prescribed for arthritis, neuralgia, and allergic reactions. It is interesting to note that with the use of sodium thiosulfate chronic alcoholics are removed from binge, since this drug is able to bind alcohol toxins.
We reviewed the instructions for sodium thiosulfate in gynecology. He is often prescribed intravenously, as well as electrophoresis. In no case should you self-medicate. This is fraught with grave consequences.