The drug "No-spa" has a strong antispasmodic effect on smooth muscles. The mechanism of activity is determined by inhibition of the phosphodiesterase enzyme. The drug is effective for spasms of both muscle and neurogenic origin. When taking the medication, there is a decrease in the tone of the smooth muscles of the biliary tract, gastrointestinal tract, and organs of the genitourinary tract. When taken orally, the drug is completely and rapidly absorbed. The maximum concentration reaches after 45-60 minutes.
The drug "No-spa". Structure
Tablets include the active substance - drotaverine hydrochloride. The component is able to evenly distribute in the tissues, penetrate the smooth muscle cells. A slight penetration of the decay products of the substance through the placental barrier is noted. Metabolized drotaverine in the liver. It is excreted in the urine.
Means of "No-spa" (tablets). Instructions for use. Indications
The drug is recommended for cramping in internal organs, gastrointestinal ulcer, chronic gastroduodenitis. Indications include colic in the liver, manifestations of gallstone pathology, postcholecystectomy syndrome, chronic cholecystitis.
The No-Shpa medication (tablets) recommends the use of the drug for cramping in the vessels of the brain, peripheral, coronary arteries, pyelitis, urolithiasis, dyskinesia (spastic), proctitis, tenesmus. Prescribe a remedy, if necessary, to weaken uterine contractions and eliminate spasm in the neck during childbirth, as well as reduce spastic manifestations during
instrumental examinations.
The drug "No-spa" (tablets). Instructions for use. Contraindications
Do not prescribe medication for insufficiency (severe course) in the kidneys, liver, heart, under the age of six years. Contraindications include rare galactose intolerance, malabsorption syndrome, lactation, hypersensitivity to the components. Caution during treatment is observed for arterial hypotension, during pregnancy.
The medicine "No-spa" (tablets). Instructions for use. Side effects
The drug provokes a decrease in pressure, heart palpitations, constipation, nausea (rarely). Some patients have insomnia, headache, or dizziness. In a number of cases, an allergy is noted on the basis of intolerance.
If the condition worsens or in the absence of the effect of therapy, you should visit a doctor, stopping the medication. Before using the medicine, you should familiarize yourself with the annotation.
Dosage regimen
The tablets are taken orally. The average daily dosage is 120-240 mg. The total amount of the drug is divided into two or three doses. Once allowed to take no more than 80 mg. Children from six to twelve years of age are prescribed no more than 80 mg. It is recommended to take the drug twice a day. From the age of 12, the dosage is 120 mg. For children of this age, the maximum amount of medicine per day is 160 mg, divided into two or four doses.
Medication "No-spa." Price
Tablets in pharmacies can be purchased within one hundred rubles.