Amoxicillin is an antibacterial agent with a wide range of effects. It is used to treat many diseases that are provoked by bacteria sensitive to it. The drug is produced in several dosage forms, including tablets, capsules, a suspension for oral administration and a solution for intravenous administration. Its effect is enhanced by clavulanic acid or sulbactam, in this situation its effect becomes even more powerful and pronounced.
The pharmacological properties of Amoxicillin include only the bacteriostatic effect on microorganisms sensitive to it. The drug does not act on viruses or fungi. Using it for uncomplicated colds is not only pointless, but also dangerous, because there is a likelihood of resistance.
Subsequently, when he will be needed, he simply will not help. Only a medical specialist should prescribe a medicine, it is dispensed from pharmacy points only by prescription. Can I take Amoxicillin for bronchitis?
Pharmacological properties
Semisynthetic drug from the penicillin group. The spectrum of action of Amoxicillin is based on its ability to specifically inhibit the enzymes of bacterial cell membranes, which can lead to cell death and dissolution.
"Amoxicillin" perfectly fights the following microorganisms:
- Staphylococci.
- Streptococcus
- Listeria Monocytogenes.
- Enterococcus Fecal.
- Corynebacterium.
- Bacillus Anthrax.
- Asheria.
- Helicobacter pylori.
- Borrelia
- Salmonella.
- Shigella.
- Campylobacteriosis.
- Haemophilus influenzae.
- Proteus Wonderful.
- Leptospira.
- Neisseria.
- Chlamydia
- Clostridia.
- Peptostreptococcus.
- Bacteroids.
- Fusobacteria.
"Amoxicillin" is not destroyed by the influence of gastric juice and is completely absorbed from the digestive system. The maximum content in the blood is reached after one to two hours. With increasing dosage, its concentration also increases. Total absorption is not dependent on the presence of foods in the stomach.
The addition of the main active trace element with blood proteins is twenty percent. The drug is distributed throughout all body tissues. It instantly penetrates into the lung tissue, middle ear fluid, bronchial secretion, urine and bile. In elevated concentrations accumulates in the liver.
The half-life is from one to one and a half hours. In people of retirement age and infants, this period is longer. With renal failure, up to twenty hours. About sixty percent of the drug is excreted in urine, a small part in the intestines, along with feces. In the inflammatory process of the soft cerebral cavity, Amoxicillin in small concentrations can enter the blood-brain barrier and is eliminated during hemodialysis. It enters the placenta and is excreted in milk. How much to take "Amoxicillin" with bronchitis?
Indications
"Amoxicillin" can be taken in the presence of the following diseases:
- Bacterial diarrhea (a pathological condition in which the patient has frequent liquid defecation).
- Dysentery (an infectious disease characterized by general infectious intoxication syndrome and gastrointestinal tract syndrome, mainly the distal colon).
- Bowel disease of infectious etiology.
- ENT disease, which is an inflammatory process in the ear.
- Inflammation of the inner lining of the heart - endocardium.
- Damage to the mucous membrane of the sinuses.
- The inflammatory process of the pharyngeal mucosa.
- Bronchitis (a respiratory disease in which the bronchi are involved).
- Inflammation of the lung tissue, infectious etiology with damage to the alveoli and lung tissue.
- Cystitis (inflammation of the bladder).
- Genital infections.
Amoxicillin for bronchitis
When prescribing this drug for bronchial damage, doctors explain this with a positive effect and a minimum of side effects.
The medication belongs to semisynthetic penicillins and is marked by increased effectiveness in the treatment of otolaryngological infections, diseases of the gastrointestinal tract, as well as the genitourinary system. The drug is allowed to be taken in childhood. What dosage of Amoxicillin for bronchitis can a doctor prescribe?
How to take the drug?
The dosage regimen is purely individual, the treating doctor prescribes it himself. The single content of the active substance for adult patients and children over ten years of age, weighing more than forty kilograms, ranges from two hundred fifty to five hundred milligrams. In severe forms of the disease - up to one gram.
For children under two years of age, a single daily dosage is twenty milligrams per kilogram of weight. For small patients from five to ten years, one hundred twenty-five milligrams.
The interval between the use of the drug is eight hours. In people with kidney disease, the interval increases to twenty-four hours.
Treatment of bronchitis with Amoxicillin in adults:
- With this disease for adult patients, the dosage is five hundred milligrams three times a day.
- If the course of the disease is complicated, then how much medicine to take is determined by the doctor individually, but, on average, seven hundred fifty or a thousand milligrams per day of Amoxicillin with bronchitis can be prescribed.
For children from five to ten years, the drug in tablets is prescribed at a concentration of seven hundred and fifty milligrams, the dosage must be divided into three times. If a suspension is used, then fifteen milliliters per day should be taken.
This medication is part of the penicillin group, and its main advantage is a wide range of effects. "Amoxicillin" more than other drugs prescribed for the treatment of inflammation that affects the respiratory tract and respiratory system.
How many days to take Amoxicillin for bronchitis? It is recommended to use the drug for up to five days to older and younger patients, as this is one of the medicines that has a detrimental effect on pathogens.
Side effects
According to the instructions for use, "Amoxicillin" in bronchitis in adults can cause certain negative effects. On the part of the skin, the following adverse reactions may occur:
- Urticaria (skin disease, dermatitis of predominantly allergic origin, characterized by the rapid onset of severely itchy blisters).
- Erythematous rashes.
- Rhinitis (lesions of the nasal cavity).
- Conjunctivitis (an inflammatory process of the lining of the eye that is triggered by an allergy or infection).
- Photosensitivity (the phenomenon of increasing the body's sensitivity to ultraviolet or visible radiation).
- Recurrent skin disease, accompanied by the formation of spots and blisters on the skin and in the oral cavity.
- Lyell's syndrome (inflammatory and allergic pathology, characterized by a severe course and related to bullous dermatitis).
On the part of the heart and blood vessels:
- Cardiopalmus.
- Phlebitis (acute or chronic inflammation of the venous wall. May develop as a result of exposure to various factors).
- Lowering blood pressure.
In addition to these adverse reactions, the following negative phenomena may appear:
- Leukopenia (a decrease in the number of leukocytes per unit volume of blood).
- Thrombocytopenia (a condition characterized by a decrease in the number of platelets below the standard, which is accompanied by increased bleeding and problems with stopping bleeding).
- Eosinophilia (a condition in which there is an absolute or relative increase in the number of eosinophils).
- Neutropenia (reduced level of neutrophilic granulocytes in the general cellular composition of the blood to a level less than normal).
- Hemolytic anemia (erythrocyte pathology, the hallmark of which is the accelerated destruction of red blood cells).
- Glossitis (a lesion of the tongue of an inflammatory nature, which can occur as an independent disease or be a manifestation of other diseases).
- Stomatitis (damage to the oral mucosa).
- Dyspnea (violation of the frequency and depth of breathing, accompanied by a feeling of lack of air).
- Bronchospasm (a pathological condition that occurs when the smooth muscles of the bronchi are contracted and their lumen is reduced).
- Interstitial nephritis (non-infectious inflammation of the kidneys that affects the interstitial region of organ tissue).
- Hallucinations.
- Myalgia (inflammation of muscle fibers).
- Arthralgia (joint pains that are volatile in the absence of objective symptoms of joint damage).
- Muscle weakness.
- Tendonitis (inflammation and degeneration of tendon tissue).
- Tendon rupture.
- Rhabdomyolysis (a syndrome that manifests itself as a result of damage to the skeletal muscle).
- Vaginal candidiasis (fungal infection of the vaginal mucosa).
- Fever.
- Hard breath.
Interaction
With the combined use of Amoxicillin with glucosamines, laxatives and antacids, slow absorption is fixed, when used together with vitamin C, the metabolism improves.
Medicines that block tubular secretion cause an increase in the effect of Amoxicillin, while taking Methotrexate, the harmfulness of the latter increases.
When used with Metronidazole, nausea, vomiting, diarrhea, and pain in the stomach may occur.
It is strictly forbidden to use simultaneously with "Disulfiram". Caution must be exercised when co-administering Amoxicillin and anticoagulants.
Contraindications
Prohibitions on the use of the drug are the following conditions and diseases:
- Increased sensitivity to trace elements of the drug.
- Severe diseases of the digestive system.
- Acute lymphoblastic leukemia (a malignant disease of the hematopoietic system, characterized by uncontrolled proliferation of immature lymphoid cells).
- Age to three years.
- Hay fever (an allergic disease accompanied by damage to the eyes, nose, as well as the skin and respiratory tract).
- Viral infections.
Features
"Amoxicillin" with caution should be taken with a tendency to allergies. People under the age of eighteen and people who suffer from liver diseases should not use the medicine together with Metronidazole.
In case of impaired renal function, the dosage of the medication should be reduced, and the intervals between doses increased. During therapy, the functioning of the liver, kidneys and organs of the hematopoietic system should be periodically monitored. To eliminate the likelihood of complications from the digestive system, Amoxicillin should be used during meals. There is no information about the negative effect of the drug on the ability to drive a car.
How to store the drug?
Keep the drug in a dark, inaccessible place for children, at a temperature of no more than twenty-five degrees. "Amoxicillin" is dispensed in drugstores strictly by prescription.
The shelf life of the drug is thirty-six months.
Analogs
Amoxicillin has a number of substitute drugs, for example:
- Amosin.
- Flemoxin.
- "Ecobol".
- Ospamox.
- Amoxisar.
- "Ranoxyl."
The cost of Amoxicillin starts from sixty rubles.
Opinions
Almost all reviews of "Amoxicillin" with bronchitis, which are available on the network, are positive. Patients note the instant effect of taking the medicine, and that it is convenient to use.
But there is also a small percentage of negative responses in which people complain that Amoxicillin did not do its job. As a rule, this is due to the fact that the drug, although it belongs to antibacterial agents with a wide range of effects, but, unfortunately, not all harmful microorganisms are sensitive to its effect.
Therefore, before using this antibiotic, a full examination of the patient should be carried out. But these studies can spend quite a lot of time, and are usually carried out in a hospital. In practice, a medical specialist, trying to improve the general condition of the patient, prescribes therapy without examination, by and large, "at random", and sometimes makes mistakes. People believe that the lack of positive dynamics is a lack of a drug.