Stress is an integral part of our lives. Some pass quickly and without a trace for us, while others turn into serious psychological or neurotic disorders. Eliminate such symptoms will help the drug "Selank". Reviews claim that the drops are effective in combating haunting anxiety, but the medicine should be used in a course to consolidate the result.
The composition of the drug and the release form
The drug "Selank" is produced in the form of nasal drops. The description of the drug notes that 1 ml of a solution with a concentration of 0.15% contains 1.5 mg of the active component of threonyl-lysyl-prolyl-arginyl-prolyl-glycine-proline diacetate.
Drops are packaged in bottles with a convenient 3 ml dropper. The bottle is packed in a cardboard box, where, in addition to the medicine, there is an instruction for use. The solution is a liquid that does not have color and odor. The bottle contains sixty drops.
The drug is stored at t ≤ 10 ° C. It must not be frozen. The product should be stored in a cool and protected from light and children place. Shelf life is two years from the date of manufacture.
Do not use after expiration date. It is released from pharmacies strictly on prescription. It costs within five hundred rubles.
pharmachologic effect
Selank - what is it? First of all, it is a synthetic substitute for the taftcin peptide. It acts neurospecifically on the nervous system and connects to specific receptors that are located on the cell membranes of nerve endings.
It affects the metabolism of monoamines in the emotional brain system and exhibits increased activity of the brain enzymes tyrosine and tryptophan hydroxylases. Attached to the serotonergic structure, normalizes cerebral serotonin in conditions of decline. Normalizes excitation and inhibition functions. It increases the stability of neutrons in the head and prepares the human psyche for heavy loads.
The drug has an anti-anxiety, anxiolytic effect. Nasal drops do not have hypnosedative and muscle relaxant qualities. When using the medicine, there is a positive effect of both mnemonic and cognitive nature. The tool stimulates memory, improves performance, activity, removes stress, fatigue, tension and increases the ability to learn. Increases motivational processes and the adequacy of perception. Has a vegetotropic property. Increases vegetative activity with emotional stress. Optimizes the adaptive reserves of the human body, normalizes sleep. Helps to transfer air travel and climate change, time zones. Removes subnestic manifestations.
When using Selank, side and toxic effects do not provoke even with a repeated increase in dose. The medicine is not famous for locally irritating, embryotoxic, allergenic, teratogenic quality. Does not detect mutagenic properties. Drops are not addictive and addictive, but help to survive the "withdrawal" syndrome, which was caused by other drugs.
In ophthalmology, the drug gives a good result in the treatment of glaucoma, as well as atrophy of the optic nerve.
The drug “Selank” in pediatrics is involved in the treatment of minimal brain dysfunctions. It is used in children with impaired attention and hyperactivity. Also to increase the psychomotor activity of the child.
Pharmacokinetics
Selank (reviews say that the medicine is highly effective for stress and excessive anxiety) has an absolute bioavailability of 92.98%. 30 seconds after the introduction of drops into the nasal passage, the active component penetrates the blood and is absorbed through the mucous membrane of the nasal cavity. After five minutes, the concentration of the active substance begins to decline.
Metabolites with this administration of the drug are not detected. “Selank” enters the brain tissue in an instant and is equally quickly distributed throughout the body. Settles unchanged in the heart, kidneys and liver.
It is absorbed in the nose up to 70%, and then this part of the drug is distributed to all organs and tissues. The medicine penetrates the blood-brain and placental barrier. When it enters the hematopoietic environment, it degrades. It is excreted by the genitourinary system.
The drug "Selank": indications
The drug is prescribed for intellectual and mnestic disorders. The reason for use is an increase in adaptive qualities, as well as preventive measures of fatigue, when a person is forced to work in an intense rhythm for several hours. A medicine is used for traumatic brain injury and after neurosurgical operations. Drops are recommended for post-narcotic and asthenoneurotic disorders, anxiety and anxiety-asthenic symptoms, as well as for neurasthenia and difficulties in adaptation in society.
In ophthalmology, indications include atrophy of vision, neuritis, glaucoma.
Children in pediatrics are prescribed small doses of the drug for brain dysfunctions when there is a lack of attention and hyperactivity.
Contraindications
The Selank drug (reviews say that the drug quickly and effectively treats depression) has certain contraindications. These include hypersensitivity to substances in the composition of nasal drops, psychotic disorders with anxiety.
The ban is pregnancy, breastfeeding, and endocrine system diseases.
The drug "Selank": instructions for use
Drops are administered only intranasally and alternately in each nostril. Patients are asked to sit down and slightly tilt their heads back. After instilling the drug with a finger, the nasal passage should be clamped for a short time. Significantly reduce the effectiveness of the means of excretion flowing from the nose.
One administration of the medication should be equal to three drops or 300 μg of the active substance. The drug is administered in both nasal passages. If the dosage for some reason needs to be increased, then this should happen after fifteen minutes after the initial injection. Recommended one-time norms are 3-12 drops or 300-900 μg of the active ingredient. The maximum daily dosage should not exceed 900-2700 mcg. If you need to enter a lot of drops, then the reception is divided into three times. The course is 14 days. It can be repeated after 1-3 weeks.
Side effects and overdose
The drug "Selank" (0.15%) with prolonged use can cause side effects. This is a change in taste preferences, an allergic reaction, individual intolerance to the components.
Interaction with other medicines
They only talk about the positive effect that the Selank drug gives, reviews. It does not affect the effectiveness of other drugs that inhibit the central nervous system. Also, nasal drops do not interact with other medicines.
special instructions
“Selank” does not have a hypnotic and muscle relaxant property. The effect of taking the drug in healthy people who used it with excitement, anxiety, excessive fatigue came after a few minutes. This period can last from 5 to 20 minutes.
If the anxiety lasts a long time, then the duration of treatment is from one month to a year, and the result is noticeable on the third day.
With the introduction of the drug inside, the desired proportion along the pathways from the olfactory nerves goes directly to the brain, where it immediately provides the desired effect in just a few seconds. So you can quickly act on the nervous system of the brain, where the drug enters the shortest way. Upon completion of the instillation, the drug interacts with the nasal mucosa and with the flow of blood to the nerve cells of the brain. Through the olfactory nerves there is a direct interaction of the brain with the nasal mucosa.
This form of drug administration allows you to enter the maximum amount of active substance into the body and quickly remove the excitation processes, reduce serotonin in the brain. In this case, the drug does not harm the stomach, liver and intestines.
Selank Drops can be combined with antidepressants, vitamins, magnesium and B6. This will only increase the effect, but will not increase the incidence of side effects.
Nasal drops can be combined with alcohol. In this case, the medicine will reduce the toxicity of ethanol and other unpleasant consequences for the brain.
Use in healthy people is possible with depression, increased fatigue, anxiety and stress. The drug treats neuralgia of a different nature and generalized anxiety disorder.
The drug is not used during pregnancy and breastfeeding due to the lack of clinical studies at this point.
Also, drops can be taken by people, regardless of profession and occupation. During treatment, concentration of attention and coordination of movements are not disturbed, which is especially important for drivers of vehicles and people whose profession is associated with increased concentration of attention and speed of movement.
Analogs
They say that the drug "Selank" quickly removes anxiety and fear, reviews. The photo with the image of the bottle is located below.
At the moment, there are no structural analogues for Selank, which could have a similar active substance.
If the drug did not fit for some reason, then a specialist will certainly help replace it with a medicine whose properties will not be inferior to this.
Doctors reviews
Specialists have a very positive opinion about the Selank medicine. According to doctors, it removes neurasthenia well, restores sleep, reduces anxiety and removes depression. It is prescribed for the treatment of many diseases of a neurotic nature and when a “withdrawal” syndrome occurs after the use of more serious drugs, for example, such as “Phenazepam”. Consider it a fairly powerful tool. Drops in complex treatment give a good result.
Doctors say that the drug is not addictive. It acts almost instantly and leaves no negative effects. It is advised to keep in the refrigerator after purchase.
But not all experts praise the drug. Some people do not trust nasal drops and claim that they can only cope with the disease in a mild form. And they call this medicine almost a placebo. They say that no serious clinical studies have been conducted on the drug "Selank", reviews of doctors.
Patients' opinion about the medicine
Reviews about "Selanka" are only positive and neutral. That is, people to whom this medicine helped, were satisfied with the result. Nasal drops quickly removed anxiety and distraction, normalized sleep, increased efficiency, eliminated nervousness. After using them, people wanted to smile and enjoy life. They were not infuriated by the boss, relatives and friends. With ease, he removed depression, which lasted more than one week, and Selank helped to cope with anxiety and fear.
Reviews for children say that he had the most positive effect on the memory, quick-wittedness of the children. After taking the drops, the children became easier to fall asleep and sleep better, it was better to perceive new information.
Neutral reviews say that the tool does not help, it is expensive and has a relatively small bottle, which is literally enough for several applications.
Selank is a new generation tranquilizer. Helps to cope with everyday difficulties and cure many diseases. Thanks to his action, many people got the opportunity to enjoy life and not give in to despair, melancholy and anxiety.