The drug "Lokren" of the pharmacological group beta-blockers with the active substance betaxolol is available in coated tablets.
If you have been prescribed the drug "Lokren", the instructions for use contain the necessary information and provide a list of indications: the drug is used for arterial hypertension, angina pectoris, akathisia caused by neuroparalytics.
Lokren is contraindicated in cases of hypersensitivity to betaxolol or excipients, sinus bradycardia (<50 beats per minute), sinus node syndrome, arterial hypotension, cardiogenic shock, severe heart failure, severe obstructive respiratory failure and bronchial asthma, with artioventrikulyarnoy blockade of 2-3 degrees, severe Raynaud's disease, peripheral arterial occlusive diseases, in pheochromocytoma, anaphylactic reactions, metabolic acidosis e, cardiomegaly, lactose intolerance, glucose-galactose malabsorption.
With caution or in limited doses, Lokren tablets should be taken in case of chronic obstructive pulmonary disease, unstable angina pectoris, a tendency to bradycardia, degree 1 artioventricular blockade, Raynaud's peripheral circulation disturbance, diabetes mellitus in the stage of decompensation, hypoglycemia, psoriasis, and impaired liver and kidney function , hyperteriosis, muscle weakness, in the elderly and childhood, as well as during desensitizing therapy.
For the Lokren preparation, the instructions for use indicate the initial daily dose, which is half the tablet (20 mg) inside, which you do not need to chew with water without gases and various dyes.
The drug "Lokren", instructions for use during pregnancy, as well as during lactation:
Teratogenic effects of the drug "Lokren" in animal experiments have not been identified. At the moment, there have been no cases of teratogenic effect. Prospective controlled studies of congenital malformations have not been identified. Beta-adrenergic blockers have properties that reduce blood flow in the placenta, and therefore can affect the fetal development. Thus, the drug should be used during pregnancy only as a last resort, when the therapeutic benefit for the pregnant woman exceeds the possible harm done to the fetus.
Beta-blockers and betaxolol, including penetrate into breast milk, therefore, during lactation, the drug should not be used, or breast-feeding should be stopped at the time of its adoption. In any case, you need to consult a doctor.
The drug "Lokren", instructions for use when interacting with other drugs:
The drug is contraindicated with simultaneous use with flactafenin and sultoprid. It is not recommended to be taken in combination with amiodarone, with drugs that block “slow” calcium channels - depridyl, diltiazem, verapamil, as well as with cardiac glycosides, MAO inhibitors, contrast and iodine-containing drugs.
The Lokren medicine has such side effects as reactions from the nervous side (weakness, hallucinations, dizziness, tremors), cardiovascular (palpitations, sinus bradycardia, Raynaud's syndrome), digestive (nausea, diarrhea, vomiting), respiratory (nasal congestion) , bronchospasm) of the systems, as well as from the sensory organs (visual impairment) and skin (psoriasis-like reactions, excessive sweating). Allergic reactions may occur. These include weakness, fatigue, headache, drowsiness, or vice versa, insomnia. Nightmares, anxiety, depression, partial memory loss, hallucinations, tremors are also possible.