One cannot but agree that a disease such as hemorrhoids is one of the unpleasant health problems.
This pathology appears due to circulatory defects in the veins of the anus, accompanied by some specific symptoms: bleeding, pain, constipation and itching.
A decisive role in the treatment of hemorrhoids is played by a systematic approach, which includes special gymnastics, diet, complex medications and sports. One of the medicines is Relief Advance. It is a modern drug against hemorrhoids, the effect of which is to eliminate the main pathogenic signs, contributes to the speedy healing and recovery.
The drug is produced by the Italian pharmacological firm Famar CA, as well as in the USA, at the De Angeli Institute.
Composition and form of release
Relief Advance has the following dosage forms:
ointment for external and rectal use: a homogeneous mass, in which there are no extraneous inclusions, yellow-white, a specific weak aroma (in a plastic tube of 28.4 grams, in a cardboard bundle one tube with an applicator);
rectal suppositories of a torpedo-shaped, yellow-white hue or pure white (in a blister pack of six pieces, a cardboard pack includes two blisters).
The “Relief Advance” contains active ingredients: shark liver oil , benzocaine; excipients: propylene glycol, mineral oil, propyl parahydroxybenzoate, sorbitan monostearate, methyl parahydroxybenzoate, petroleum jelly.
One suppository contains active ingredients: shark liver oil, benzocaine; excipients: propyl parahydroxybenzoate, corn starch, cocoa butter, solid fat, methyl parahydroxybenzoate.
Pharmacodynamics
So, does Relief Advance cure or only anesthetize? The drug is used in proctology locally. It produces anesthetic, wound healing and anti-inflammatory effects. Its mechanism is determined by the properties of the substances included in its composition:
Benzocaine: produces an anesthetic local effect, not being a source of resorption;
shark liver oil: has immunomodulatory, hemostatic, wound healing and anti-inflammatory activity;
cocoa butter: is the basis of suppositories, additionally producing a softening effect.
Indications for use
Relief Advance is used for:
The drug is used for pain relief after surgical interventions in proctology, as well as during the implementation of diagnostic procedures.
Indications "Relief Advance" are described in detail in the instructions.
Contraindications
Among the contraindications are the following conditions:
- thromboembolism;
- granulocytopenia;
- hypersensitivity to substances in the composition.
In accordance with the instructions, the drug with extreme caution and only as prescribed by a specialist can be used during pregnancy, breastfeeding and treatment of children under twelve years of age.
Instructions for use
Candles "Relief Advance" are used by introducing them into the anus.
They must be used in the morning, at night, and also after the next bowel movement (intestinal emptying), after conducting preliminary hygiene procedures. The following dosage is recommended for patients over twelve: one piece not more than four times a day. The duration of therapy is determined individually.
Ointment for external and rectal use is used by applying a thin layer of the drug to the ananal affected area, is directly injected into the anus. Manipulation is carried out thanks to the applicator, which is attached and attached to the tube. First you need to lubricate it, squeezing the ointment in a small amount, and then enter into the anus.
After each use, the applicator must be removed, washed thoroughly, and then inserted into the protective cap. The multiplicity of procedures is recommended as follows: up to four times a day (in the morning, afternoon, in the evening and after the next bowel movement).
When using Relief Advance suppositories, local and allergic reactions in the form of itching and hyperemia may develop.
Overdose
According to the instructions for use with Relief Advance, the alleged side effects may be due to systemic absorption of benzocaine, which is part of the drug, and include excitement, anxiety, drowsiness; in severe situations - cramps; in very rare cases, methemoglobinemia, which is manifested by cyanosis and respiratory disorders.
If the daily and single dosage of shark liver oil, which is part of the drug, is significantly exceeded, a tendency to increased blood coagulation may develop.
With methemoglobinemia, the following treatment is required: blue methylene is administered intravenously.
special instructions
If copious discharge of blood comes from the rectum or painful symptoms persist for longer than a week, additional consultation with a proctologist is required.
There is also evidence that drugs that contain benzocaine can cause methemoglobinemia. Some signs, for example, cyanosis of nails, lips and skin, dizziness, headache, shortness of breath (shortness of breath), tachycardia, weakness observed during therapy, can indicate a potentially life-threatening methemoglobinemia of the patient. She needs urgent medical attention.
In order to minimize systemic adverse events, the recommended daily dosage cannot be exceeded unless otherwise prescribed by a specialist.
The drug is not recommended for use on damaged skin, as this can enhance systemic absorption.
Avoid the interaction of the drug with latex products (contraceptive condoms and diaphragms) in order to avoid a decrease in their effectiveness.
The drug does not affect the ability to control mechanisms and vehicles.
Relief Advance is used during pregnancy and breastfeeding only in special situations when the expected effect of treating a woman is much higher than the potential danger to the child or fetus.
Drug interaction
In clinical practice, no interactions with other drugs have been described. In order to avoid the expected side effects and achieve the maximum therapeutic effect, it is not recommended to use other ointments and suppositories during the use of the medication or to observe a sufficient interval between doses.
Shelf life and storage features
The drug should be protected from access by children. It is stored at a temperature not exceeding 27 ° C in a place protected from moisture and light. The shelf life of Advance Relief is two years.
Analogs
The pharmacological market is replete with many drugs for hemorrhoids. Often they are characterized by a similar composition and therapeutic effect.
The drug "Relief Ultra" is a popular American analogue, which is available in the form of suppositories. Like Relief Advance, it is made on the basis of shark liver oil, however, in addition to this substance, hydrocortisone contains acetate and zinc sulfate monohydrate. Thanks to this factor, suppositories produce a complex and more pronounced therapeutic effect. They are prescribed both for hemorrhoids and for the treatment of perinatal dermatitis, eczema and proctitis. The price ranges from 350 to 370 rubles.
Betiol is a Russian combined inexpensive product that is produced in the form of suppositories. It is made on the basis of ichthyol and belladonna extract. It has anti-edematous, anti-inflammatory and antispasmodic effects. It is made by Dalchimpharm. Cost - from 80 to 90 rubles.
"Proctosan" - a medicine for hemorrhoids from Germany, which contains lidocaine, titanium dioxide, bismuth subgallate, bufexamak. It is prescribed for hemorrhoids and anal fissures. Thanks to the drug contained in lidocaine, it perfectly eliminates pain. Cost - from 360 to 390 rubles.
"Anuzol" - the medicine is produced in Nizhny Novgorod, the company "Nizhpharm." Available in the form of suppositories (Neo-Anuzole and Anuzole). They contain bismuth tribromphenate, zinc sulfate and belladonna extract. It produces analgesic, anti-inflammatory, antiseptic, drying, astringent and antispasmodic effects. Cost - within one hundred rubles.
The drug "Hepazolone" is another Russian analogue, which is manufactured by Altpharm LLC. It is available in the form of rectal suppositories that contain sodium heparin, lidocaine and prednisolone. The medicine produces a venosclerosing and anti-inflammatory effect. The average price is about 260 rubles.
It should be noted that the above analogues are given here for informational purposes only. You can not self-medicate and choose drugs on your own. Be sure to consult a specialist before use.
Reviews
“Relief Advance” as a whole has proven itself very positively, which is confirmed by numerous reviews of medical workers and patients.
Many of them note a noticeable therapeutic effect after using the drug. It well eliminates the unpleasant signs of hemorrhoids.
The medicine rarely causes allergic reactions and is most often well tolerated by patients. The reviews of the Relief Advance confirm this.
The drug is included in the middle category at a cost, so many people can afford it.
Thus, this drug is a popular and modern medicine that has established itself well. It copes with the negative signs of hemorrhoids and contributes to recovery.