How should I use the drug "Desal"? Instructions for use, indications for the use of the mentioned funds will be considered in this article. You will also learn about the forms in which this medication can be purchased, how it affects the human body, and more.
Forms of release, description of the drug, its composition and packaging
Among patients, the most popular are Desal allergy pills. Film-coated, they contain such an active substance as desloratadine. In addition, the preparation also includes auxiliary elements in the form of magnesium stearate, microcrystalline cellulose, talc, pregelatinized corn starch and mannitol.
Tablets are sold in packs of cardboard in 10 or 30 pieces.
In addition to the aforementioned form of the drug, another type of the “Desal” preparation is produced. The solution (instructions for using the drug will be discussed below) is mistakenly called a syrup. It is transparent, colorless and free from foreign particles. The active substance of this form is also desloratadine. As for auxiliary components, they include Tutti-Frutti flavoring, sorbitol, disodium edetate, propylene glycol, sucralose, citric acid monohydrate, hypromellose and sodium citrate dihydrate.
Children's solution "Desal" (syrup) goes on sale in bottles of dark glass (50, 100, 60, 150, 120 or 300 ml each). Also included is a measuring spoon (5 or 2.5 ml) or a syringe dispenser (5 ml).
Pharmacological characteristics of the drug
What is the medicine "Desal"? Instructions for use states that it is a long-acting antihistamine . It is a blocker of histamine peripheral H1 receptors. The active substance of the drug is the primary active metabolite of loratadine. Desloratadine inhibits allergic reactions and also releases pro-inflammatory cytokines and chemokines.
Due to its pharmacological properties, the Desal preparation prevents the development of allergic reactions, prevents their course, has an antiexudative and antipruritic effect, prevents the development of tissue edema, reduces capillary permeability, and prevents smooth muscle spasms.
It is impossible not to say that the medication in question does not have a negative effect on the nervous system, does not have a sedative effect, does not affect the speed of psychomotor reactions and does not cause drowsiness.
The action of the main substance begins 30 minutes after administration and continues throughout the day.
Pharmacokinetics of the drug
How long does Desal take? Reviews of experts say that after taking the drug inside, desloratadine is absorbed quite quickly from the digestive tract. It is determined in the blood after half an hour, and its maximum concentration is reached after about three hours.
Communication with proteins is about 85-89%. The simultaneous intake of water or food does not affect the distribution of desloratadine. It does not penetrate the BBB.
The terminal phase of the half-life is 27 hours. The drug is excreted in the form of a glucuronide compound along with feces and urine.
Indications for use
When is Desal prescribed? Instructions for use indicate that this medication is used to alleviate and also eliminate the following symptoms:
- urticaria, including skin itching and rash;
- allergic rhinitis, including sneezing, nasal congestion, rhinorrhea, itchy nose, itchy palate, itching and redness of the eyes, lacrimation.
Contraindications to the use of the medication
This drug should not be prescribed for:
- breastfeeding;
- in childhood (patients under 12 years old);
- pregnancy
- hypersensitivity to any substances of the drug.
It should also be noted that with extreme caution, the drug in question is prescribed for renal failure (severe).
Medication "Desal": instructions for use
At what dosage is the Desal medicine prescribed? In tablet form, such a drug is taken orally, regardless of food intake. For adolescents, as well as adults, the medication is prescribed 5 mg or one tablet once a day.
As for the solution, it is also taken orally, regardless of the meal. Babies 1-5 years old are given 2.5 ml of syrup once a day. Children 6-11 years old are prescribed 5 ml of the solution once a day. Adolescents and adults are allowed to take 10 ml of the drug.
Overdose
According to experts, the medication taken in a dosage that is 9 times higher than recommended does not lead to any side effects. However, in rare cases, patients have developed drowsiness. As a treatment, gastric lavage is used. Also, the patient may be prescribed taking activated charcoal.
Adverse reactions
According to patient reviews, taking the drug in question can cause side effects. Among the most often manifested are the following:
- hallucinations;
- dizziness, insomnia, drowsiness, and psychomotor hyperactivity;
- abdominal pain, dyspepsia, nausea, diarrhea, and vomiting;
- tachycardia and palpitations;
- hepatitis, increased bilirubin concentration and liver enzyme activity;
- myalgia;
- anaphylaxis, pruritus, angioedema, urticaria and rash.
Drug interaction
To date, no clinically significant interaction with other medications has been identified (including with Erythromycin and Ketoconazole).
It should also be noted that the active substance of the drug does not enhance the action of ethanol on the nervous system.
Lactation and pregnancy
The appointment of the drug in question during pregnancy is not recommended, since there is no clinical information about the safety of its use during this period.
Desloratadine easily passes into breast milk. In this regard, its use during lactation is prohibited.
special instructions
If the patient has severe renal impairment, then the drug "Desal" should be prescribed with extreme caution.
The medication does not have any effect on the person’s ability to drive transport. However, it should be borne in mind that quite rarely drowsiness develops in some patients. In this case, extreme caution should be exercised when driving and working with complex and dangerous machinery.
Analogues of the drug, the price of the drug
Antiallergic drug "Desal" can be purchased at any pharmacy. It should be noted that its price is quite high (according to most patients). For 30 tablets you will have to give about 360 Russian rubles. The drug in the form of a solution has approximately the same cost.
If the drug "Desal" is contraindicated for the patient, then it can be replaced with an analog. The following drugs are characterized by the same composition and action: Desloratadine, Nalorius, Lordestine, Ezlor, and Elyseus.
Before replacing the prescribed remedy with an analogue, it is imperative to consult a doctor. This is due to the fact that such drugs may have other side effects and contraindications, as well as dosages and methods of use.
The drug "Desal": patient reviews
Before taking this allergy remedy, we recommend that you carefully read not only the attached instructions, but also the patient reviews. Thanks to such information, you can find out how to properly take the drug in question and in what dosage.
Reviews about the drug "Desal" (for allergies) are mostly positive. Patients claim that after several doses of such a drug, the symptoms of urticaria disappear almost immediately, skin itching and rash disappear. Also this medicine perfectly treats allergic rhinitis. It quickly eliminates congestion, itching in the nose and other signs of the aforementioned disease.
However, in addition to the positive, this drug has negative reviews. According to them, it is ineffective, and sometimes does not have any effect on the allergic reactions that have arisen.
Experts say that this happens only with improper use of the medication, as well as in the absence of the allergy itself. Therefore, before using the drug in question, you should definitely consult a doctor and establish an accurate diagnosis (that is, find out if you really have an allergy or is it any other disease that manifests itself in a similar way). Do not be ill!