"Clemastine" is an antihistamine intended for oral use and parenteral use. The antihistamine effect of the drug is manifested by blocking certain receptors.
pharmachologic effect
"Clemastine" instructions for use are characterized as a medicine that has a drying effect on the skin, eliminating itching, swelling and allergic reactions.
The drug prevents vasodilation, eliminates the contraction of smooth muscles that occur due to the action of histamine. Capillaries become less permeable, cholinergic receptors located in peripheral tissues and the central nervous system are blocked. "Clemastine" describes the instructions for use as a tool that has a moderately pronounced sedative effect. In addition, it provides local anesthesia.
With internal use, the drug is well absorbed in the digestive tract. The highest concentration of the drug in the body is observed on average three hours after it is taken, and the maximum effect is six hours later. The desired effect can be observed up to 12 hours, sometimes 24 hours. Metabolism occurs in the liver. The drug enters the urine and is excreted mainly in the form of metabolites. When used during lactation, “Clemastine” is present in milk.
In what cases is the drug used?
"Clemastine" instructions for use can be taken orally and parenterally.
Internal use
Due to the internal use of the drug, hay fever and serum sickness are eliminated , dermatitis (contact, itching) and eczema, which is acute and becomes chronic , are treated. Therapy leads to the disappearance of vasomotor rhinitis and allergic rhinitis etiology, allows you to remove skin itching, hives, allergic reactions that occur after insect bites. "Clemastine" successfully copes with drug exanthema and hemorrhagic vasculitis. As a result of its use, acute iridocyclitis is cured.
Parenteral administration
Parenteral administration of the drug is used in order to prevent the manifestation of allergies and pseudoallergy. Thus, angioedema is removed , it is possible to carry out complex therapy of anaphylactoid and anaphylactic shock.
Contraindications
"Tavegil" ("Clemastine") the instruction for use prohibits taking with increased sensitivity to the components of the product. It is not prescribed for pregnant women and patients who breast-feed a baby. The medicine is not suitable for the treatment of pathologies in which sections of the respiratory tract located in the lower sections are affected.
Children under six years of age are not prescribed Clemastine tablets. The instructions for the use of injections of the drug and syrup are defined as contraindicated for the treatment of children under 1 year old.
Limitations
Restrictions are necessary for prostatic hypertrophy, which provokes the development of problems with urination, a stomach ulcer (stenosing).
Restrictions are established for obstructions affecting the bladder in the neck and duodenum, diseases of the cardiovascular system. They are used in the presence of hyperthyroidism, closed glaucoma.
Dosage and route of administration
After penetration into the body, the drug begins to act quickly enough, after a maximum of one hour. With the internal use of Clemastine, the method of application and dose are as follows:
- patients who are at least twelve years old take 20 ml syrup twice a day before meals, which corresponds to 1.5 tbsp. l funds, or 1 mg of the drug (daily dose) present in one tablet (if necessary, increase the daily dose of syrup to 120 ml);
- children from six years to twelve years old take the drug twice (in the morning, before bedtime) at a dose of not less than 0.5 mg and not more than 1 mg;
- children from one year to three years are given 1 tsp. funds in the form of a syrup, children over four years to six years can be prescribed 2 tsp. syrup, and after seven and up to twelve years - 1 tbsp. l
In those cases where the medication was missed, it is taken immediately. If you need to take the next dose soon, the previous one is skipped and the established treatment regimen is observed. In such situations, it is forbidden to double the dose.
Parenteral use of the drug is possible twice a day both in the treatment of adult patients (i / v) and in the treatment of children (i / m). The recommended dosage is 2 mg and 25 μg per 1 kg of weight for adults and children, respectively.
"Clemastine" instructions for use allows you to take as necessary.
Side effects
Side effects can be manifested by problems with urination, dizziness, and visual impairment. Convulsions and hallucinations are possible. Some patients have impaired coordination and confusion.
There is a possibility of drying out of the membranes lining the larynx, nose and mouth, and thickening of mucus. Other side effects may include nausea and drowsiness. In rare cases, headache develops, constipation or diarrhea, vomiting are present. A person can be irritable and restless. Increased sweating is sometimes noted. The patient can quickly get tired, nasal congestion and chills are possible.
special instructions
When using the Clemastine product, the instructions for use, price, and safety precautions are mandatory information.
Therapy eliminates the possibility of alcohol intake and driving. Keep in mind that the drug may affect the safety of certain activities. In the treatment of elderly patients and children under six years of age, the drug is used with caution.
Before carrying out some types of allergic testing, termination of treatment with Clemastine is required for 72 hours.
So that the medicine does not irritate the walls of the stomach, it must be consumed with food, washed down with milk or water. To eliminate drowsiness, you can drink tea and coffee. Pieces of ice, caramel with a sour taste and chewing gum without sugar in the composition perfectly manage dry mouth.
Drug interaction
The drug is incompatible with sleeping pills and MAO inhibitors. It enhances the effect of sedatives, barbiturates, anticholinergics, antipsychotics, anesthetic drugs and other drugs that depress the central nervous system. By interacting with certain drugs, the drug may weaken their effect.
Analogs, price, reviews
Analogs of the drug for the active substance are "Tavegil", "Bravegil", "Rivtagil", "Clemastine-Eskom", "Clemastine Fumarate". If necessary, after consulting with your doctor, you can pick up an analogue of Clemastine. Instructions for use, the price of the tablet makes it a profitable and convenient tool for use. Domestic tablets can be purchased for 70 rubles, Swiss, Bulgarian, Italian and Polish drugs of the same form - for 75-180 rubles. The cost of syrup (India) is approximately 180 rubles per 100 ml of funds.
Some customers consider Clemastine and its analogs to be obsolete products that cannot do their job. Many note the effectiveness of the drug in eliminating allergies. Often in the reviews there is information that “Clemastine” is one of the most effective drugs and eliminates the manifestations of any allergic reactions, even when it is not possible to do this using other means.