Modern people are increasingly suffering from a sleep disorder such as insomnia. This condition is characterized by insufficient duration, or unsatisfactory quality of sleep, or a combination of the listed phenomena that continues for a long time.
The causes of this disorder may be different. Most often, they include severe overwork, noisy or too light rooms, various diseases and so on.
To eliminate insomnia, most people use sleeping pills. The most effective of them is the Ivadal medication. Instructions for use, analogues, properties and features of this medication will be described below.
Packaging, release form, description and composition
In what form is the Ivadal sleeping pill made? The medicine for insomnia can be found in the form of white oblong tablets with a fault line, as well as the engraving "SN 10" on one side. They are film-coated and contain such an active ingredient as zolpidem tartrate.
As additional components, the preparation under consideration includes lactose monohydrate, magnesium stearate, microcrystalline cellulose, hypromellose, and sodium carboxymethyl starch. The film membrane includes hypromellose, macrogol 400 and titanium dioxide.
You can buy this tool in blisters embedded in cardboard packs.
Pharmacodynamic characteristics
What are Ivadal tablets? The instruction says that this is a sleeping pill from the group of imidazopyridines. In their pharmacological activity, they are very close to benzodiazepines.
This medication has effects similar to other drugs of the same group: anxiolytic, muscle relaxant, hypnotic, sedative, amnestic and anticonvulsant.
The principle of action of the drug in question is associated with a specific agonistic effect on central ω-receptors, which belong to the macromolecular GABA-receptor complexes, which cause the opening of neuronal anion channels for the entry of chlorine.
The active substance of this drug selectively interacts with benzodiazepine receptors, so the sedative effect of the drug is already observed at small doses.
In a patient, zolpidem shortens the period of falling asleep, and also reduces the number of night awakenings, increases the total duration of sleep and improves its quality.
A sufficient concentration of this agent in the blood provides a sleep lasting 8 hours.
This drug has low toxicity. Moreover, it is not addictive, does not contribute to anterograde amnesia, morning weakness and daytime sleepiness.
Drug kinetics
Is Ivadal sleeping pill absorbed? Instructions for use, reviews report that when administered, the drug in question is rapidly absorbed from the digestive tract. The peak concentration of the drug in the blood is observed after 2.5 hours. Its bioavailability is 70%, and its association with plasma proteins is 92%.
The drug metabolism is carried out in the liver. Its inactive metabolites are excreted mainly with urine and feces within 2.5 hours.
Indications
What disorders require Ivadal tablets? Reviews of doctors report that this medication is very effective in:
- night awakenings;
- chronic sleep disturbances;
- situational and transient insomnia associated with stressful situations;
- sleep disorders that are associated with difficulty in falling asleep.
Contraindications
In which cases, Ivadal sleeping pills should not be used? Instructions for use report contraindications such as:
- sleep apnea;
- severe respiratory failure;
- minor age;
- the period of pregnancy in the first trimester;
- breast-feeding;
- hypersensitivity to the drug;
- lactase deficiency, galactosemia, galactose or glucose intolerance.
It should also be noted that only for strict indications the drug in question is prescribed in the second and third trimesters of pregnancy, with violations in the liver, as well as with drug addiction, alcoholism and myasthenia gravis.
Ivadal tablets: instructions for use
The drug in question is taken orally immediately before bedtime. For people under 65 years of age, this medication is prescribed at a dose of 10 mg, and over a specified age - 5 mg.
The duration of treatment with this remedy for situational insomnia is 2–4 days. With short-term insomnia, the drug is taken for up to three weeks, but not more than one month.
The duration of therapy for chronic insomnia is determined by the doctor.
According to experts, the drug "Ivadal", the analogues of which are listed below, can not be taken in high doses and in combination with other sleeping pills, including benzodiazepines. Its long and continuous reception is also forbidden.
Side effects
Does Ivadal sleeping pills cause side effects? Customer reviews report that such reactions are extremely rare. As a rule, they include the following:
- headaches;
- nightmares;
- memory impairment ;
- drowsiness in the daytime;
- diplopia;
- gait disturbance;
- confusion of consciousness;
- rash and itching on the skin;
- vomiting, abdominal pain, and stool disorders.
Overdose of pills
What signs of overdose can the Ivadal medication cause? The instruction for use states that in this case, impaired consciousness (inhibition and confusion), up to a coma, are manifested, and ataxia, hypotension and respiratory depression are also observed.
To eliminate such conditions, the victim provokes vomiting and washed the stomach. Sorbents are also prescribed and support respiratory function.
Interaction with other means
Can Ivadal sleeping pills be combined with other medicines? Instructions for use informs that this product can not be used in conjunction with ethyl alcohol.
Respiratory depression and central nervous system can be observed while taking barbiturates, antipsychotics, sleeping pills, sedative antidepressants, morphine derivatives, antihistamines and antiepileptic drugs, as well as drugs for anesthesia and central antihypertensive drugs.
Special recommendations
Before appointing the Ivadal sleeping pill, it is imperative to establish the true cause of sleep disturbances.
The persistence of insomnia for two weeks after the start of therapy indicates the presence of mental disorders or disorders of the National Assembly. To identify such deviations, a regular reassessment of the patient's condition is required.
The use of zolpidem in people with signs of depression requires caution.
The use of alcohol and other drugs with a depressing effect on the central nervous system, as well as taking medication in high doses increases the risk of developing abnormal behavior.
After a course of taking the drug for several weeks, there is a slight decrease in its sleeping pills and sedative effects.
Analogs and price
The cost of sleeping pills "Ivadal" in the amount of 20 tablets can be 2600-3500 rubles. If necessary, the drug in question is replaced with such drugs as Snovitel, Hypnogen, Zolpidem, Zolsana, Zonadin, Sanval, Oniria, Nitrest.
Reviews
Insomnia significantly reduces the quality of life of any person. Modern sleeping pills are quite effective in the treatment of chronic and short-term sleep disorders. One of them includes the drug "Ivadal."
According to consumer reviews, this tool even in the smallest dose contributes to the early onset of sleep. Moreover, after awakening, the medication does not cause a feeling of lethargy, fatigue and fatigue.
Most patients use this medicine situationally, that is, as needed.
Consumers argue that this medication is well tolerated with strict adherence to the regime and does not cause addiction.