The action of the Teturam tablets (the instructions for use contains such data) is due to the blockade of acetaldehyde dehydrogenase involved in the metabolism of ethyl alcohol. Due to the activity of the medication, the concentration of the decay product - acetaldehyde, which provokes the negative effects of alcohol intake (tachycardia, vomiting, nausea, flushing of the face, lowering pressure and others) increases. As a result, drinking alcohol becomes extremely unpleasant. This produces a conditioned reflex aversion to alcohol.
Indications
Prevention and treatment with Teturam are prescribed to eliminate relapses in chronic alcoholism. As a detoxifying agent, the drug is recommended for nickel poisoning (chronic type).
Contraindications
The drug "Teturam" (instructions, reviews of experts confirm this) is not recommended for thyrotoxicosis, hypersensitivity, stage decompensation of pathologies of the cardiovascular system (with pronounced cardiosclerosis, post-infarction conditions, coronary insufficiency, aortic aneurysm, atherosclerosis in the cerebral vessels, insufficiency, ) Contraindications include asthma, pulmonary tuberculosis, lesions in the gastrointestinal mucosa, diseases of a neuropsychic nature, epilepsy, pronounced emphysema . “Teturam” medicine is not recommended for use in case of glaucoma, neuritis in the auditory and optic nerves, infectious lesions in the central nervous system, polyneuropathy. No medication is prescribed for ulcerative lesions in the digestive tract, during lactation, with malignant tumors, during pregnancy.
Caution in the treatment and prophylaxis is shown with residual effects on the background of circulatory disorders of the brain, endarteritis, after the age of 60 years, as well as in the presence of data (in history) about psychoses on the basis of taking disulfiram.
The drug "Teturam." Instructions for use
Therapy is prescribed only after a thorough diagnosis, patient warnings about complications and consequences. The medicine is taken orally. Dosage - twice a day, 150-500 mg. A week later, a teturamalcoholic test is carried out: after taking 500 mg of the drug, the patient is given 20-30 ml of vodka. In the case of a weak reaction, the dosage of alcohol increases by another 10-20 ml. The repetition of the test is carried out in a day or two in stationary conditions or after 3-5 days in an outpatient setting with the correction of the amount of the drug and alcohol as necessary. Subsequently, a maintenance dosage of the drug is used - 150-200 mg / day for 1-3 years.
Means "Teturam". Instructions for use. Side effects
Due to prevention or treatment, a mouthfeel of metal in the mouth, halitosis (associated with carbon disulfide) in patients with a colostomy can occur. The drug can provoke hepatitis, neuropsychiatric disorders, polyneuropathy in the lower extremities, disorientation in space and time, disorders of the neuropsychiatric type. Against the background of taking the medication, headache, skin allergy, asthenia can be noted.