According to the instructions, "Asparkam Aveksima", "Asparkam" and other options for the release of this medication are intended for the treatment of cardiac ischemia. The tool belongs to the group of auxiliary. Differences in name are due to the fact that different companies release their own Asparkam variants, and for ease of product identification, additional letters are added to the name.
Pharmacological characteristics
In the instructions for use of Asparkam, the manufacturer indicates that the pronounced effect is ensured by the presence of L-asparaginate in the preparation. This substance, once in the human body, takes part in the movement of magnesium and potassium ions. Thanks to the proper use of the product, the transportation of ions within the cells can be adjusted.
Due to magnesium, the AT phase of sodium and potassium is activated, the cell is purified from sodium ions, filled with potassium. In the instructions for use of "Asparkam" it is also mentioned that the active component of the tablets inhibits the sodium-calcium metabolism in the muscle vascular fibers, which means that the resistance becomes somewhat lower. Under the influence of potassium, the production of ATP, protein structures, as well as glycogen, acetylcholine is activated. Potassium and magnesium ions are responsible for the polarization of cell membranes.
Multifaceted effect
The manufacturer in the instructions for use "Asparkam" indicates that the tool allows you to adjust the impulse conduction, that is, affects the functioning of nerve fibers and the transmission of synapses. In addition, through "Asparkam" you can normalize the contractility of muscle tissue, normalize and stabilize the work of the heart muscle.
Magnesium ions in the composition of the drug take part in the generation, expenditure of energy reserves. Due to their adequate concentration in the body, cell membranes receive a normal level of permeability. Neuromuscular conduction is stabilized. The active substances that Asparkam supplies to the human body allow you to control the processes of RNA, DNA production, cell growth and division. In the instructions for use of Asparkam, the manufacturer indicates an improvement in the digestibility of oxygen molecules under the influence of the active compounds of the drug. Phosphate production is becoming more active.
Drug kinetics
Instructions for use "Asparkam" states that magnesium and potassium ions are able to be absorbed very quickly, after which they are distributed over organic tissues. Almost a third of all incoming magnesium in the blood serum forms strong bonds with protein structures. Magnesium and potassium with urine are eliminated, a relatively small percentage with intestinal contents. Small volumes are excreted with secretions of sweat, lacrimal, salivary glands and other substances secreted by the body.
In the instructions for use of Asparkam, attention is drawn to the fact that the elimination process can be somewhat slower if the kidney functionality is lower than normal.
What's on sale
In pharmacies, “Asparkam” is present in two release options - tablets for oral administration and liquid for injection into a vein.
The solution is sold packaged in ampoules, the volume of the container is from 5 to 20 ml. In one cardboard box contains 5-10 ampoules "Asparkama", instructions.
The active components of the solution are 3.37 mg of magnesium, 10.33 mg of potassium. Both substances are included in the preparation in the form of aspartates.
The second option is tablet. It also contains aspartates: magnesium - 175 mg, potassium - the same amount. One cardboard box contains Asparkam tablets, instructions for use. In the package - from one to ten blisters.
Features and Surplus
The instructions for Asparkam stated that the substance can reduce the effectiveness of glycosides for the heart. In the form of a solution, the drug cannot be used if the patient has an increased susceptibility to sorbitol.
When combined with diuretics aimed at preserving potassium in the body, there is a possibility of accumulation of excess potassium in the circulatory system. This can provoke asystole, arrhythmia. This can lead to a combination with drugs based on spironolactone, triamteren. Similar effects can be observed with an excessively high dose of "Asparkam" on the background of the use of cyclosporins, ACE inhibitors, beta-blockers, non-hormonal drugs to relieve inflammation. Excess potassium in the body can be observed against the background of the use of the described drug and heparin.
Against the background of the use of GCS, there is a risk of a lack of potassium in the body. Asparkam corrects this condition. The severity of side effects of cardiac glycosides is reduced.
What Potassium Magnesium May Affect
It is very important that you carefully follow the instructions for use of Asparkam. Reviews of cardiologists indicate that the tool, although effective, but in combination with a number of drugs can cause an inadequate response of the body. You can prevent such a development of the situation if you strictly follow the manufacturer's recommendations.
It is noted that the presence of magnesium ions in Asparkam reduces the effectiveness of drug therapy if the drug is used simultaneously with streptomycin, tetracycline, neomycin, and polymyxin.
Studies have shown that some painkillers activate the negative effects of magnesium on the central nervous system. The combination with muscle relaxants can cause a more pronounced blockade of nerves, muscle fibers. This makes it necessary to use Asparkam and preparations containing decametonium, suxamethonium, and atracurium compounds extremely carefully at the same time.
The effectiveness of magnesium present in Asparkam becomes lower with calcium supplementation. The content of magnesium in the circulatory system increases if the medication and calcitriols are combined.
In the instructions to Asparkam, the manufacturer indicates that the drug is combined with cardiac glycosides in the form of a solution for injection. Such a combination leads to better tolerance of these medicines.
Terms of Use: Injection
In this form, the instruction for Asparkam recommends using the drug for administration by drops or by jet infusion. The dosage is chosen by the doctor, based on the individual characteristics of a particular patient. It is necessary to focus on the availability of evidence. Drops Asparks must be administered at a rate of 25 drops in 60 seconds. The frequency of the procedure is once or twice a day. The volume of a single injection is 10-20 ml.
Before use, Asparkam is diluted in sodium chloride or five percent glucose. Use 100-200 ml of liquid.
If necessary, the injection of 10 ml of the substance is diluted with glucose solution and slowly poured into a vein. The maximum speed is 5 ml in 60 seconds.
Tablet form: how to apply
The instruction for Asparkam tablets recommends using the drug three times a day after a meal, one tablet or two, which depends on the clinical manifestations of the disease. The duration of the therapeutic program is 3-4 weeks. It is allowed to repeat the course, if there is evidence for this.
Contraindications
The instructions to Asparkam contain a ban on the use of the drug if excess magnesium or potassium is observed in the body. It is not allowed to use the product with hypersensitivity or intolerance to any substance used by the manufacturer when receiving the medication.
"Asparkam" is forbidden to persons who have revealed insufficient kidney function in acute, chronic form, impaired functioning of the adrenal cortex. Do not use the medication for oliguria, anuria, severe myasthenia gravis. The drug is not suitable for people suffering from dehydration, Addison's disorders, low blood pressure.
"Asparkam" is prohibited in the second, third degree of atrioventricular block, with acute acidosis. The tool is not used for cardiogenic shock.
As can be seen from the numerous reviews dedicated to the Asparkam solution and tablets, according to the instructions, the product is not used during pregnancy and lactation. If you need to use the composition in such conditions, you should consult a doctor to choose a safer alternative. The described medication is also not suitable for minors, since there is no information on its effectiveness and safety in such a group of patients.
Specificity of use
There have been no studies designed to determine whether Asparkam is able to adjust the rate of psychomotor reactions. There is no data on whether the drug affects a person’s ability to drive vehicles and machines, units that require high concentration and fast, accurate response. There is no information about the possibility of use during a period when a person is engaged in potentially dangerous activities. The manufacturer warns about all this in the instructions for use of Asparkam. In the reviews, it is noted that the medicine is prescribed, recommending that you behave more carefully in everyday life, without exposing yourself to unnecessary risk.
Is it worth buying
As noted in numerous reviews, the instructions for "Asparkam" are quite understandable, so those who were prescribed the drug did not have difficulties with its proper use. Many note that the use of the medication was accompanied by a significant improvement in the general condition.
As can be seen from the reviews, in the instructions for the use of Asparkam tablets, the manufacturer indicates the need to consult a doctor first, only after that use the product. Those who neglect this recommendation are more likely to experience side effects. In addition, the doctor explains how to mitigate the negative consequences of using the medicine, with which response the body needs to urgently cancel Asparkam. People who use the drug without consulting a specialist do not have access to such information, so the use of the composition is often accompanied by side effects.
When will help
The main indications for the use of Asparkam are a lack of magnesium and potassium in the body.
Often, a medication is prescribed as an element of complex therapy for heart ischemia. The drug allows you to stabilize the condition of a patient who has had an acute heart attack in the recent past. The tool allows you to normalize blood flow in the heart muscle, so it is used for chronic failure.
"Asparkam" allows you to smooth out the manifestations of malfunctions of rhythm, heart rate. The drug is prescribed for arrhythmias due to excessive content of cardiac glycosides in the body.
Overdose than dangerous
There is a chance of an overdose. If you use Asparkam in an unreasonably large dose or inject it into a vein too quickly, there is an excess of potassium in the blood. This condition expresses itself with reduced muscle tone, paresthesia of the limbs. Atrioventricular conduction decreases, the rhythm of the heartbeat goes astray.
Excess Asparkam in the body can lead to the accumulation of excess magnesium. This condition is noticeable by hyperemia of the skin of the integument, a decrease in pressure. The patient is thirsty, impulse transmission is impaired, the functioning of the center responsible for breathing is inhibited. The rhythm of the heartbeat goes astray, a convulsive state is observed.
In case of an overdose, it is necessary to use calcium chloride or gluconate for intravenous infusion. Dosage is determined based on the severity of the symptoms. Additionally, measures must be taken to support respiratory function and blood dynamics. The doctor chooses therapy based on their characteristics of the symptoms in a particular case. Efficiency is shown by dialysis, including blood.
Features of the composition
In addition to the active component, Asparkam tablets contain a wide range of additional compounds. It is important to familiarize yourself with all these substances to people suffering from allergic reactions to pharmaceutical products. It should be borne in mind that Asparkam tablets contain talc, starch, and calcium stearate.
For solutions, the manufacturer uses sorbitol and special water.
In some forms of release, the active components are supplemented with polyvinylpyrrolidone, sugar.
Negative consequences
Asparkam can cause nausea and vomiting. In some patients, against the background of the use of the drug, stool is broken, the stomach hurts. Perhaps the appearance of ulceration sites on the mucous membrane of the stomach, intestinal tract, as well as bleeding in this area.
"Asparkam" can provoke activation of gas separation, dry mucous membranes of the oral cavity. Some patients experience a paradoxical reaction. There is a risk of lowering pressure, bradycardia, phlebitis. There may be blood clots in the veins. There is a risk of skin reactions - certain areas may itch. According to reviews, some patients were dizzy, others were disturbed by dyspnea.
"Asparkam" can provoke asthenia, myasthenia gravis, paresthesia. Against the background of the use of the drug, the work of sweat glands can be activated. There is a risk of hyporeflexia, AV blockade.
Asparkam: analogues
There are not many drugs on the domestic pharmaceutical market that have the same composition as the drug in question. The instructions for use indicate that the active components of Asparkam are magnesium and potassium asparaginate. The action of the Panangin remedy is based on them. In addition, the drug “Potassium and magnesium asparaginate” is on sale.
According to reviews, the instructions for Asparkam and the analogues mentioned above are quite similar: the products are intended for use in the same pathological conditions. Distinctive features of the composition are few. However, this does not mean that you can safely replace the drug prescribed by your doctor with another one similar to it. This approach can cause a negative response of the body and the ineffectiveness of drug therapy.
Before starting a therapeutic course, it is wise to familiarize yourself with the instructions for use of Asparkam and analogues, with reviews of these drugs. This will make it possible to make a general impression about which remedy from the drugs on the pharmaceutical market is more suitable, how reasonable it is to replace a medication prescribed by a doctor with a cheaper one. After analyzing the available information, you should consult a doctor, explain why the patient wants to replace “Asparkam” with an analogue. The specialist will say whether it is reasonable in a particular situation, which of the alternatives is more suitable. Another analogue of the drug in question is Pamaton.
Asparkam in sports
The official instructions for the use of instructions on the possibility of using the drug by athletes in order to maintain the strength of the body are not. However, some trainers believe that the tool can be used if it is necessary to withstand increased physical activity for a long time. "Asparkam" is believed to help maintain the strength of the body if a person is forced to work hard for a long time.
In some cases, “Asparkam” is used for too active and hard training. You can use it if sports loads have caused a violation of the rhythm of the heartbeat. "Asparkam" is indicated for neurocirculatory dystonia.
Recommendations of specialists
Asparkam tablets do not need to chew or break the integrity of the shell in any other way. The drug is washed down with a reasonable amount of pure water without additives.
As a prophylactic to prevent shortages in the body of potassium, magnesium, a tablet is used three times a day. "Asparkam" is taken after a meal. A similar program is recommended to their wards by trainers.
If “Asparkam” is used for 4 weeks or more, it is necessary to regularly check the content of magnesium and potassium in the circulatory system. It is recommended to take biosamples for analysis weekly or every two weeks. As soon as the parameters reach the upper acceptable limit, the drug is temporarily discontinued. They return to “Asparkam” when the content of potassium and magnesium in the circulatory system decreases again.
It is not allowed to use more than 6 Asparkam capsules per day. Excessive amounts of active components lead to intoxication of kidney cells.
Tender age
It is extremely rare that Asparkam is used to normalize the body condition of children of different ages, including infants.The drug can be used if there is a lack of potassium in the circulatory system, it is not possible to use safer and more reliable options for normalizing the amount of trace elements. Before administering Asparkam, laboratory blood quality indicators must be carefully checked. As a rule, injecting is only allowed if refusing such a procedure poses a threat to the life of the child.