The drug
"Xarelto" describes the
instructions for use as a means of being an anticoagulant of direct action. Moreover, the direct inhibition of factor Xa is the basis of this drug. In addition, this drug has a fairly high selectivity. As for its pharmacokinetics, it is very rapidly absorbed, reaching a maximum concentration in the blood two to four hours after oral administration. If we talk about the features of the removal of this highly selective drug, then together with urine and feces, about 92-95% of the Xarelto medication is excreted. Instructions for use (the price, by the way, for this remedy is about 1,500 rubles), however, notes that the remaining part leaves the body unchanged through renal excretion.
This anticoagulant is produced in the form of round tablets of dark pink or red-brown color, containing ten, fifteen or twenty milligrams of micronized rivaroxaban in its composition. Auxiliary components are substances such as croscarmellose
sodium, sodium lauryl sulfate, hypromellose 5cP, microcrystalline cellulose,
magnesium stearate and lactose monohydrate. The composition of the shell includes
titanium dioxide, macrogol 3350 and red iron oxide. In addition, 5cP hypromellose is contained in a small amount.
To prescribe Xarelto tablets, the instruction for use generally recommends to patients who have previously undergone surgical procedures on the lower extremities. For this category of people, this anticoagulant will act as an effective prophylactic agent for the development of future venous thromboembolism. In addition, the drug "Xarelto" is excellent for preventing relapse of DVT and pulmonary embolism. Also, this tool should be used to prevent stroke in people with non-valvular atrial fibrillation . To prevent the development of systemic thromboembolism and the treatment of deep vein thrombosis and acute obstruction of the pulmonary artery, Xarelto tablets are also recommended for use.
Use of this anticoagulant is strictly contraindicated for people with gastrointestinal, intracranial or any other type of bleeding, severe renal failure or galactose intolerance. If the patient has an increased sensitivity to rivaroxaban or an allergic reaction to other excipients presented in the composition, it is also not worth taking the drug "Xarelto". Instructions for use categorically prohibit prescribing it during pregnancy. Contraindications are
lactose intolerance, the use of other anticoagulants, liver diseases accompanied by coagulopathy, and conditions associated with a high risk of major bleeding. In addition, you should not take this medicine to women who are breast-feeding, or to persons under the age of eighteen.