Ibuprofen ointment is included in the category of non-steroidal anti-inflammatory drugs (non-narcotic analgesics). The drug has analgesic, anti-inflammatory and moderate antipyretic properties. Ibuprofen ointment helps suppress the production of inflammatory mediators.
The mechanism of action of the drug is associated with the process of inhibition of prostaglandin synthesis and inhibition of cyclooxygenase.
The use of the drug Ibuprofen ointment helps to weaken or disappear the pain syndrome, which includes the manifestation of pain during movement or rest in the joints. In addition, the drug reduces swelling of the joints and reduces morning stiffness, contributes to an increase in motor volume in diseases of a non-rheumatic and rheumatic nature affecting the musculoskeletal system. Ibuprofen ointment is used for patients with various pathological conditions, has a high degree of dosage flexibility and various forms of release.
When using the medication, absolute absorption from the gastrointestinal tract occurs. In plasma, its maximum concentration is reached after one to three hours. 99% of the drug binds to plasma proteins. In the liver, the drug is metabolized to inactive metabolites. 90% of the dose taken is partially excreted by the kidneys in free form. Partial isolation occurs as conjugates. A small volume is secreted with bile. The order of two hours is the half-life. After a day, the process of complete elimination is completed.
The medication is used to relieve pain and inflammatory processes of a moderate nature. The drug is indicated for rheumatic pains, lumbago, arthritis, expressed slightly, back pain, fibrositis, muscle pain, and also with sprains.
Ibuprofen ointment. Instructions for use
The drug is applied externally to the area of the painful area three or four times a day. In this case, it is recommended to carefully rub the medication until completely absorbed into the skin. The ointment is applied in a strip of five or ten centimeters.
The duration of the course of treatment is selected in accordance with the severity and nature of the lesion. In severe cases, it is advisable to use the medication in combination with oral administration of anti-inflammatory non-steroid medications.
As side effects, in rare cases, localized allergic reactions can occur, expressed in flushing of the skin, a tingling sensation or burning sensation.
Contraindications to the use of the medication include eczema, weeping dermatoses, wounds and abrasions with the presence of infection. The drug is not used by persons with hypersensitivity to the components of the drug, as well as to other NSAIDs.
The use of the drug in the antenatal period is not recommended. The appointment of the drug in this case can only be justified by the attending physician. Despite the low concentration of the components of the drug in breast milk and their insignificant effect on the health of the child, due to the lack of clinical data on the safety of the use of the drug during lactation, it is recommended to refuse to breast-feed for the treatment period. Or another drug may be prescribed.
When using the medication Ibuprofen ointment, the instruction does not recommend applying it to mucous membranes or open wounds.
According to some experts, the medication used by patients after myocardial infarction can provoke a relapse of the attack or increase the risk of death. It should be noted that this conclusion applies to the entire category of non-steroidal medicines.