Is “ACC” effective against cough? You can find reviews about this medication a little further. Also from the materials of this article you will learn about the form in which this medicine is produced, what components are included in its composition, how it works and whether it has side effects.
Form, composition, description, packaging of a mucolytic agent
In what form can I buy the drug “ACC” for cough? Effervescent tablets are available in aluminum tubes and strips, have a white color, the aroma of berries or fruits, as well as a round and flat shape.
Also, the medication in question is available in powder form. It is intended for the preparation of a medicinal solution for oral administration. On sale, this form comes in bags, which are placed in a package of cardboard.
If the medication is prescribed for young children, then they are recommended to give “ACC” cough syrup. This form of the drug is sold in dark jars with a measuring spoon.
The active ingredient of all of these funds is acetylcysteine. It is its presence in the drug that determines the high therapeutic efficacy of the drug.
Pharmacological effect of the drug on cough
How does the “ACC” for cough? The instruction says that it is a mucolytic agent.
Taking the drug helps to thin the sputum, increase its volume, facilitate secretion and subsequent expectoration.
The principle of action of the drug “ACC” is associated with its ability to break all disulfide bonds of mucopolysaccharides of sputum (acidic). This effect leads to a decrease in the viscosity of mucus and the depolarization of mucoproteins.
It should be especially noted that this drug remains active even in the presence of purulent sputum.
Features of an expectorant medication
How does the “ACC” cough medicine affect the human body? Effervescent tablets, as well as syrup and powder have an antioxidant effect, which is due to the presence of the SH-group, which is able to interact, as well as neutralize oxidative electrophilic toxins.
The active substance of the drug helps to increase the synthesis of glutathione, which is an important antioxidant factor for intracellular protection. It provides support for the morphological integrity and functional activity of the cell.
Pharmacokinetics Mucolytic
Is the drug “ACC” absorbed from cough (the price of this agent is indicated below)? According to the instructions, when taken orally, this medication is fairly well absorbed from the intestines. To a large extent, it undergoes the first passage through the liver. This leads to a decrease in its bioavailability.
Communication with plasma proteins is about 50% (about 4 hours after administration). The drug is metabolized in the liver, as well as in the intestinal wall. In the blood, acetylcysteine is observed unchanged, as well as in the form of the following metabolites: N, N-diacetylcysteine, cysteine ester and N-acetylcysteine.
Indications for use
Many patients know how effectively the “ACC” helps cough. Reviews of experts say that the indications for the use of this drug are all conditions and diseases in which there is an accumulation of sputum in the respiratory tract.
Thus, it can be safely noted that the mentioned medication effectively treats:
- tracheitis;
- chronic and acute bronchitis;
- bronchiolitis;
- sinusitis;
- obstructive bronchitis;
- laryngitis;
- bronchiectatic disease;
- cystic fibrosis;
- bronchial asthma;
- otitis media is exudative.
By the way, dry cough “ACC” does not cure. It should be used only with sputum that is difficult to separate (that is, with a wet cough).
Contraindications
Under what conditions is it impossible to prescribe the drug “ACC” for cough? Reviews of experts say that the following diseases are contraindications to the use of this medication:
- peptic ulcer;
- fructose intolerance;
- renal failure and hepatitis (especially for children);
- bleeding from the lungs.
It should also be noted that this medication is not recommended for use with hypersensitivity of the patient to the components of the drug.
How to take the drug “ACC” for cough?
Reviews of experts report that the dosage of this medication directly depends on the indications.
Treatment of cystic fibrosis - for people with a body weight of more than 30 kg, the daily dosage is 800 mg. For children from the 10th day of life and up to 2 years old, the drug is given 50 mg three times a day, and for children 2-5 years old - 400 mg per day.
The daily dosage of this medicine is divided into several doses.
“ACC” for children from cough (6-12 years old) is prescribed in the amount of 600 mg. The course of therapy is usually 3-6 months.
For other diseases, this drug should be taken according to a different scheme. To clarify it, you need to undergo a medical examination and consult your doctor.
For adults and adolescents over 12 years of age, the drug is prescribed in a dosage of 400-600 mg per day.
Therapy for the uncomplicated course of the disease should last for 5-7 days. If the disease is chronic or complicated, then the course of treatment can be significantly increased (up to six months).
According to the attached instructions, this drug should be taken strictly after eating. The “ACC” powder, as well as effervescent tablets, must first be dissolved in 100 ml of any liquid (for example, in water, tea or juice).
As for baby syrup, it should be given to the child without dilution. The dosage of this form of medication is determined by means of a measuring spoon.
Side effects
The use of the drug “ACC” can provoke the appearance of such side effects as diarrhea, heartburn, nausea, stomatitis and vomiting. It should also be noted that this medication often contributes to the development of tinnitus, headaches, increased blood pressure and arrhythmias.
Overdose cases
In the event of a deliberate or erroneous overdose of this drug, patients may experience symptoms such as vomiting, diarrhea, heartburn, stomach pain, and nausea. The listed symptoms do not require drug withdrawal and after a while pass on their own.
Drug interaction
With the simultaneous administration of “ACC” with antitussive agents, life-threatening stagnation of mucus may occur. This is due to the suppression of the cough reflex.
The combination of nitroglycerin and acetylcysteine can enhance the vasodilating effect of the former.
The drug “ACC” reduces the absorption of tetracycline, cephalosporins and penicillins. In this regard, the above funds should be taken 2 hours after taking acetylcysteine.
“ACC” is not compatible with antibiotics and proteolytic enzymes.
The interaction of acetylcysteine with rubber and metals produces sulfides, which have a characteristic odor.
The drug “ACC” for cough: price and analogues
You can replace the drug in question with one of the following funds: “Fluimucil”, licorice root syrup, “Atsestad”, “Mukaltin”, “Mukoneks”, “Solvin”, “Acetylcysteine Sediko”, “Gedelix”, “Acestine”, “Bromgexin-Fereyn ”,“ Lazolvanom ”,“ Bromhexine-Acre ”,“ Ambrobene ”,“ Libexin Muko ”,“ Ambrol ”,“ Mucosol ”,“ Bronkatar ”.
As for the price, it can vary slightly between different forms of this drug. For example, you can buy powder for 170 rubles, syrup for 230, and effervescent tablets for 250.
Reviews about the mucolytic agent
According to patient reviews, this drug is highly effective. He completely copes with the task. When taking the recommended dosages, a wet cough goes away within a few days. As for more serious diseases, it takes a little longer to treat them.
There are practically no negative reviews for this medication. Although some patients still complain of its inefficiency. Doctors explain this fact with an incorrect treatment regimen or a complex course of the disease.