In the article we will understand why Sinaflan ointment is used.
This medication is not intended for long-term treatment. This ointment should be used with great care and only after consulting a dermatologist. The doctor will prescribe an individual dosage regimen immediately after the examination of the patient.
Drug description
Sinaflan ointment was synthesized by scientists several decades ago, but its use is still relevant in dermatology. The low content of the active ingredient makes it possible to reduce the likelihood of systemic manifestation. But at the same time, this amount is enough to quickly eliminate the symptoms of skin disease. The presented drug may have a diverse positive effect on the condition of any layer of the epidermis. What helps this ointment? The presented medicine performs the following functions:
- It stops the inflammatory processes that occur under the influence of internal and external negative factors.
- Reduces the severity of edema, preventing their spread to areas with healthy tissues.
- When applying Sinaflan ointment, anesthetizing effect is observed externally, which lasts for several hours.
The active component of this medication can accumulate in the tissue affected by inflammation. Due to this, the analgesic, and at the same time, decongestant effect, as a rule, persists for two weeks after discontinuation of the drug.
Mechanism of action
So, what is the mechanism of the pharmacological effect of Sinaflan ointment? It is as follows:
- The process of inhibiting phospholipases, which is responsible for the progression of the inflammatory process.
- Stabilization of the cell membrane along with the prevention of increased swelling of the tissue. What is Sinaflan ointment used for?
- Acceleration of metabolic breakdown of proteins.
- Decreased migration of macrophages and white blood cells into damaged tissues.
- Reducing the activity of hyaluronidase enzymes, which destroys hyaluronic acid.
- Decreased arachidonic acid production.
- Lowering the need for glucose in skin tissue.
- Decreased ability of cells to absorb calcium.
- Retention of sodium and liquid ions in tissues.
Rapid stopping of Sinaflan ointment of inflammatory reactions leads to accelerated tissue regeneration. It receives biologically active and nutrient substances, and in addition, molecular oxygen. The elimination of the deficiency of beneficial compounds leads to the gradual restoration of the affected skin pathology.
What is the composition of Sinaflan ointment?
Release forms and composition
The presented drug is produced by many domestic pharmacological factories. The Sinaflan therapeutic line includes ointment, liniment, cream and gel. Preparations are packaged in 10 and 15 grams in aluminum sealed tubes. The ointment is a uniform dense mass with a yellowish tint, which does not have a specific smell. In gel and cream, the consistency is more delicate, while in liniment it is dense.
In the composition of Sinaflan ointment, in addition to the active component of fluocinolone acetonide, there are auxiliary substances in the form of paraffin, petrolatum, propylene glycol, lanolin and ceresin. The secondary packaging for all Sinaflan dosage forms is a cardboard box, to which detailed instructions for using the medicine are attached.
Storage conditions
The shelf life of the Sinaflan ointment is five years, but immediately after opening the tube, it is limited to three weeks. The drug is stored at room temperature. It must be kept in a place protected from sunlight.
Instruction manual
The instructions for use recommend the use of Sinaflan ointment exclusively as directed by a doctor. This drug effectively eliminates any allergic rashes of various localization. This remedy is prescribed by dermatologists with uncomplicated inflammatory dermatitis.
In case of violation of the integrity of the skin, the likelihood of joining a bacterial, viral or fungal infection increases. In such cases, Sinaflan is combined with various antibiotics, antiviral or antimycotic drugs.
Cancel this therapeutic ointment should be gradual. The dosages used are reduced for several days, or the medicine is mixed with a baby cream. In case of non-compliance with this rule, there are risks of exacerbation of skin pathologies.
Indications
Sinaflan ointment is included in the therapeutic regimens of patients diagnosed with eczema or psoriasis. It is used to treat lichen planus, erythema multiforme, and in addition, it is used for allergic rashes. This drug can also be prescribed for the following pathologies of the skin: with dermatitis, first-degree burns, inflammation after insect bites, neurodermatitis, seborrhea, and skin itching of various etiologies.
Contraindications
Sinaflan medicine is not intended for the treatment of cutaneous tuberculosis and syphilitic manifestations. This ointment is not used to treat acne and trophic ulcers. It is forbidden to apply this medicine on skin with open wounds. One of the strict contraindications to the use of this therapeutic ointment is various tumors, regardless of their benignity.
Method of application and dosage of ointment
The duration of the therapeutic course is determined by the attending physician, who selects the dosage individually for each patient. Sinaflan is undesirable to use for more than five days. Treatment can be extended up to ten days if there is an urgent need. A single dosage corresponds to three centimeters of a strip of external agent. The medicine is applied to the areas affected by inflammation four times.
Ointment should be lightly rubbed into the skin. Dermatologists recommend pre-treating the skin with antiseptic solutions, for example, Chlorhexidine, Miramistin or Furacilin is suitable. This will certainly enhance the therapeutic effect of the ointment and will reduce the overall duration of the course of therapy. Do not apply it under an airtight dressing.
Analogues of Sinaflan ointment will be presented below.
Side effects
The belonging of the ointment to hormonal drugs determines a wide list of its possible side effects. Sometimes local reactions occur, especially in case of violation of the dosage regimen. Clinically, they can manifest as follows:
- Following the application of the ointment, burning, itching, swelling and redness intensify.
- Small rashes appear on the skin, and in addition, steroid acne and papules.
- The upper layer of the epidermis intensely flakes, discolored areas appear.
- Hair begins to fall abundantly.
In the event that the duration of therapy recommended by the doctor is exceeded, systemic side effects may be observed. Hormonal drugs negatively affect the gastric mucosa and provoke its ulceration. Various forms of ulcers and gastritis may occur. Adrenal function is impaired, glucose levels increase in urine, and steroid diabetes develops. In particular, the use of local hormonal drugs affects immunity:
- Resistance to bacterial, viral and fungal infections decreases.
- The process of repairing damaged tissue is slowed down.
- Various chronic pathologies are exacerbated.
People suffering from arterial hypertension should use this ointment in treatment with caution. Prolonged application of Sinaflan ointment, according to reviews, often provokes a rise in pressure.
During pregnancy
The use of almost all hormonal drugs is prohibited during gestation. Doctors prescribe Sinaflan ointment during pregnancy only after a preliminary comparison of the possible harm to the child with the benefit to the mother. In such cases, women are recommended to use the ointment in the minimum dosage.
During periods of breastfeeding, hormonal ointment is also not used. The active component of the drug passes into breast milk, and then it is in the body of the child. It can cause a neurological disorder.
If you need to use this drug, breastfeeding stops for a while. Doctors often replace Sinaflan with safer non-hormonal analogues. For example, Fenistil perfectly copes with neurodermatitis.
Sinaflan ointment for children
The medication is forbidden to be used in the treatment of children until they are two years old. Treatment of a child with hormonal drugs is carried out only under the supervision of a doctor. In children, vascular permeability is significantly increased, so the probability of the main substance getting into the blood is very high. This can extremely negatively affect the child’s immature immune system.
Children Sinaflan ointment is often prescribed for use only in combination with a fat cream. Ointment in such situations is mixed in a one to one proportion, and the resulting product is rubbed lightly into the skin of the child.
Cost
All dosage forms of this drug are released from pharmacies, subject to the presentation of a medical prescription form. The minimum cost of this ointment is twenty-three rubles.
Analogues of ointment "Sinaflan"
Analogues of this ointment are prescribed to patients suffering from individual intolerance to its components. Flutsinar is perfect for this, along with Uniderm, Triderm, Belosalik, Celestoderm and others.
Reviews
As people write in their reviews, Sinaflan ointment always saves them in the presence of exacerbations of neurodermatitis. It quite well eliminates itching along with swelling and redness of the skin. Some complain about the inconvenience that during lactation, doctors categorically prohibit its use, which should be borne in mind by lactating women.
Also in the reviews, people write that if you do not abuse Sinaflan, then no adverse reactions occur. People praise this medicine for its help in relieving symptoms of contact dermatitis due to relapse. It is noted that the itch along with burning, swelling and rashes disappear after the first application of the drug.