"Klenzit S": reviews, indications, instructions for use, composition, side effects

In the article, we will review reviews about Klenzite C and the instructions for the drug.

In the case when conventional medications used to eliminate acne are ineffective, doctors advise using stronger medications, for example, those belonging to the retinoid group.

Gel "Klenzit S" allows you to solve several skin problems at once, since it combines the antibacterial properties and the properties of adapalene retinoid.

The composition of this drug

"Klenzit S" is a combined medicine designed to eliminate acne. It contains 0.1% adaptale and 1% clindamycin. Adapalene is a synthetic analogue of retinoic acid. Clindamycin is a substance with a pronounced antibacterial effect.

The drug is produced by the manufacturer in a single pharmacological form - in the form of a gel. Thus, the name cream or ointment in the root is not true.

The Klenzita S package contains 1 tube of 1 mg + 10 mg / 1 g of gel of 15 g or 30 g each.

The gel has a light structure, is absorbed quickly into the skin, after which it immediately begins to affect.

Adapalene is a substance belonging to the group of retinoids. It has important properties for acne-affected skin properties:

1. It is able to dissolve sebaceous plugs in the pores of the skin.
2. Helps prevent the accumulation of dead cells on the epidermis.
3. Significantly reduces the production of sebum.
4. It stops the development of inflammation.

Thus, adaptale acts on the main cause of pore blockage - excessive secretion of sebum, hyperkeratosis (a phenomenon in which dead skin cells linger on the surface of the epidermis).

A detailed description of Clenzite C can be found in the annotation.

Clindamycin is an antibacterial substance of semisynthetic origin. It belongs to the group of lincosamides. Clindamycin is active against coccal and anaerobic microorganisms. They, most often, are the cause of the appearance of a stubborn and plentiful acne. In addition, clindamycin has a bacteriostatic effect, that is, it is able to stop the growth of bacteria due to the destruction of their protein structures. As a result, the inflammatory process decreases, infection of the sebaceous glands is eliminated, acne regression is observed.

A similar combination of components in Klenzit S allows the use of a medicinal gel for the treatment of severe acne, accompanied by uncontrolled formation of comedones and bacterial inflammation.

Pharmacodynamics of the drug

Adapalene acts by binding to specific skin receptors. At this stage, the differentiation of skin cells occurs. That is, the substance acts exclusively on damaged epidermal cells, without affecting healthy ones. Getting into the mouth of hair follicles, the substance reduces the cohesion of epithelial cells, thereby preventing the formation of small comedones.

The anti-inflammatory effect of adapalene is based on stopping the conversion of arachidonic acid to prostaglandins, which cause and support the inflammation process.

Clindamycin is highly effective against bacteria that provoke acne - propionobacteria. However, other microorganisms that can live and multiply on the surface of the skin are sensitive to clindamycin. Quite often, it is they that provoke the inflammatory process in the sebaceous glands.

The main effect of the substance is bacteriostatic. However, a bactericidal effect against certain bacteria may also occur if clindamycin is used in high doses.

The simultaneous inclusion of these substances in the composition of the drug gives it powerful efficacy against inflammatory processes.

Adapalene and clindamycin perfectly complement each other, while simultaneously affecting the various causes of acne. As a result, a more significant effect is observed.

Indications for the use of "Klenzita S"

The drug gel is recommended for the treatment of moderate or severe acne. The disease at these stages is characterized by the extensive appearance of closed and open comedones, as well as subcutaneous, purulent and inflamed acne.

If necessary, the medication can be used to treat rashes not only on the skin of the face, but in other parts of the body.

It does not make sense to treat mild acne with such a potent drug as Klenzit C. In these cases, dermatologists recommend the use of monopreparations, for example, “Dalacin”, “Klindovit”, “Baziron AS”, “Skinoren”.

Contraindications to the use of the drug

Sometimes there are situations in which the use of "Klenzita C" for acne is contraindicated. These include:

1. The presence of increased individual hypersensitivity to any component that is part of the gel.
2. Period of pregnancy.
3. The period of breastfeeding.
4. The presence of skin lesions at the intended site of application of the drug gel.
5. The presence of vitamin A hypervitaminosis with the use of other retinol-containing drugs.

This is confirmed by the instructions for use with Klenzit S.

Caution should be exercised in using the product for dermatitis or eczema, as well as if there are dry and flaky skin areas.

The parallel use of Klenzit S and agents that provoke dry skin are excluded.

The use of a medication to treat acne

The drug "Klenzit C" from acne should be applied only to the skin, previously cleaned and dried. Recommended single or double application during the day. If a single use is indicated, then it is better to apply it at night. When applying the gel to the skin in the daytime, it is important for two hours after that not to wash and do not use makeup.

The gel should be applied only to those areas of the skin where inflammation is localized, a rash is located, that is, locally or pointwise. Apply the medication with light movements, carefully distributing it over the entire affected surface. Rubbing should be avoided, but the medicine should cover the entire area of ​​the skin with a thin layer. Excessively applied drug negatively affects the integument, burning sensation and dryness may occur.

Very often from "Klenzita S" the skin is flaky.

The duration of use should be determined by the doctor who recommended it. Most often, experts recommend using the drug for 1-2 months. Treatment should not be delayed for a period of more than three months. This limitation is due to the fact that with prolonged use, microorganisms can acquire immunity to the gel.

After achieving a lasting effect from the use of “Klenzit S”, it is recommended to replace the drug with “Klenzit”, which contains only adapalene, there is no antibacterial component in it.

The appearance of severe irritation due to the use of gel (ointment) "Klenzit S" suggests that therapy should be stopped. You can continue it when these symptoms disappear.

Features of drug therapy

There are several features of treatment using this drug:

1. As a rule, at the initial stage of treatment, acne is activated, and the visual condition of the skin noticeably worsens. Do not be afraid of this. A similar reaction indicates the onset of the gel - it draws the infection from the deep layers of the skin to its surface. If there are concerns about such manifestations, you should consult a doctor.
2. Under the influence of adapalene, the sensitivity of the skin to ultraviolet rays increases. Accordingly, treatment with this drug in the summer is not recommended. At the time of therapy should also refuse to visit the solarium. Among other things, maximum measures should be taken to protect the skin from sunlight at any time of the year.
3. In parallel with the use of Klenzit S medicinal gel, it is necessary to moisturize the skin with special means. To do this, you can purchase Dexpanthenol, Panthenol or Bepanten at the pharmacy. They should be applied after half an hour after applying Klenzit S.
4. If other drugs are used to treat acne, it is necessary to separate their use in time. That is, if Klenzit S is used before bedtime, then an alternative remedy should be used in the morning.
5. If the medication accidentally enters the eyes or mucous membranes, rinse them immediately with running water.

The mechanism of action of the drug gel

Reviews about "Klenzit S" are mostly positive. This is due to the effectiveness of adapalene, the effect of which is enhanced by clindamycin.

Already at the initial stages of therapy, positive changes in the condition of the skin can be noted, such as:

1. Greasy luster disappears, the oily skin is significantly reduced.
2. New acne and comedones cease to appear.
3. Already appeared comedones disappear as a result of cleansing the mouths of the sebaceous glands and dissolving the plugs.
4. The number of dead epidermal cells on the surface of the skin decreases, due to which skin softening is observed.
5. The inflammatory process gradually disappears.
6. The balance of skin microflora is restored, as a result of which local immunity is strengthened.

Klenzit S and Klenzit - comparison of analogues

Pharmacy chains offer consumers two drugs that have similar names: Klenzit S and Klenzit. Despite the similarity of the names, the differences between the drugs are significant, so you should pay attention to the name when buying and purchase exactly what was recommended by the doctor.

Drugs differ from each other, primarily in their composition. In "Klenzit" contains only adapalene, "Klenzit C", in turn, contains adaptale and clindamycin.

Differences in the composition cause various indications for use in these medicines. Klenzit is recommended for use in mild inflammatory processes, when only open and closed comedones are localized on the skin. And “Klenzit C” should be used if the acne is severe, and the inflammation is pronounced.

Sometimes, experts recommend starting treatment with Klenzit C, and then, after eliminating acute symptoms, switching to Klenzit to maintain the achieved result.

Gel overdose

If you use "Klenzit S" according to the instructions, that is, exclusively locally, then an overdose cannot occur. However, the condition of the skin during the use of the gel can sometimes worsen. This happens if you take vitamin A-rich preparations at the same time, or use products that dry your skin (for example, alcohol-based products).

Side effects of "Klenzita S"

In the quality of side effects from the use of a medicinal gel for acne can occur:

1. Irritation of the skin.
2. Extremely dry skin.
3. Peeling.
4. Burning at the place of application of the gel.
5. Itching

If severe irritation develops during the use of the drug, the patient should suspend treatment until all symptoms disappear, or reduce the frequency of use (if it was used twice a day, reduce it to once, if used once a day, reduce to one every two days).

What else does the instructions for use of Klenzit S tell us?

Interaction with other drugs

Clindamycin, which is part of the drug, is an antagonist of erythromycin. Accordingly, their parallel use should be avoided.

The medical gel goes well with acne products based on benzoyl peroxide, for example, with Baziron AS cream. Very often, dermatologists prescribe their combined use.

Consider the treatment of "Klenzitom C" scars and spots.

The use of the drug from spots and scars

The gel does not have a special directed effect on the elimination of scars remaining after acne. Scars after acne remain atrophic (fossa), the formation of which occurs due to a lack of collagen in the skin. “Klenzit S” is not capable of influencing this process. That is, in the fight against acne scars, it is ineffective.

A slightly better result can be achieved if you use "Klenzit C" in relation to spots remaining after acne. The drug is able to lighten the skin somewhat and exfoliate the upper layer of the epidermis. Thus, the skin tone is gradually leveled, spots from acne become less noticeable.

Analogs

Analogs "Klenzita S", combining clindamycin and adapalene, the drug does not have. In this case, an analogue of the drug can be called a tool that incorporates one of these components. Among the analogues based on adapalene, one can distinguish “Adolen”, “Adaklin”, “Adapalen”, “Differin”. Clindamycin based analogues of Klenzit S are Clindamycin, Clindovit, Dalacin.

During pregnancy

The absorption of adapalene with external application is only 4%. However, the active substances of the drug are able to penetrate the placenta and into breast milk. In this regard, the use of "Klenzita C" during pregnancy and lactation is prohibited.

Vitamin A, even in small doses (adaptalen is a synthetic analogue of vitamin A), can provoke fetal pathologies, thereby adversely affecting the baby’s health. If a nursing woman has an urgent need to use a medication, she should stop breastfeeding.

Cost, expiration dates

The average cost of a tube with 15 g of therapeutic gel varies at the level of 750 rubles. Klenzit S should be stored in a dark place at a temperature of less than 23 degrees Celsius. If storage conditions are met, the gel retains its therapeutic properties for 3 years. After the expiration date, the use of the drug is prohibited.

Below we will consider reviews about "Klenzit S".

Reviews of cosmetologists and patients about this drug

Doctors note the high effectiveness of the drug, the positive effect of which is noticeable already at the initial stages of its use. Beauticians note that “Klenzit S” quickly stops the inflammation of the skin, prevents the appearance of new rashes, significantly improves the relief and color of the skin. Also, the drug is effective not only against acne, but also able to fight subcutaneous acne. Experts note the particular importance of following the recommendations in the instructions for the drug. If you stick to them, then a positive result from using the medication will not take long. Beauticians also note the high effectiveness of the gel against acne that appears on the back. Moreover, the skin on the back is less sensitive than on the face. Respectively. Side effects in this case are practically eliminated.

Patients, in turn, note that “Klenzit C” is more effective than most drugs intended for the treatment of acne, and recommend it despite its high cost. However, it is important to remember that it has a very strong effect, so its use must be agreed with a dermatologist. Patients also note that in the first days of applying the gel, deterioration of the skin appeared (a warning about this is available in the instructions). If you do not stop treatment at this moment, then after a couple of weeks noticeable improvements occur. The skin is smoothed, acne and acne disappear, spots from acne become much lighter, oily sheen disappears.

Many patients also in reviews of "Klenzit S" note that against the background of the use of the drug, strong peeling often appears in the field of application of the drug. The occurrence of such a side effect can be avoided if you strictly follow the doctor’s recommendations and the rules for using the gel indicated in the instructions.