In the article, we will consider the instructions and reviews for the Isofra preparation.
One of the most popular means in the fight against the common cold is the French drug Isofra. It is effective for sinusitis, as well as rhinopharyngitis, which are of bacterial origin. Symptoms of the disease stop on the third day of use. This drug is most often prescribed in pediatrics, as it is safe and can be used in children from a very young age. The drug has a minimal number of contraindications, it does not cause systemic side effects.
Reviews about "Isofra" are abundant.
Instruction for use
The undoubted effectiveness of the drug is indicated by the fact that pediatricians often prescribe it. Against the background of the use of the drug, painful symptoms quickly disappear, nasal passages congestion disappears, and full recovery occurs record fast. In connection with this, the logical question arises as to whether Isofra, like most antimicrobial medicines, belongs to the group of antibiotics or not?
The answer to this question is yes. Yes, Isofra is an antibiotic in the aminoglycoside group. Refers to neomycin derivatives. The medication can be used exclusively locally in otolaryngology, or in combination with other means in proctology and ophthalmology.
According to reviews, Isofra is also suitable for children.
But due to the fact that the product is an antibiotic, it should be used with caution, after consulting with a specialist.
Pharmacological group, composition of the drug
"Isofra" refers to aminoglycosides. The main component in its composition is framycetin, which is a structural component of the first generation of antibiotic aminoglycosides. ABP is intended exclusively for topical use in ENT.
As already noted, the main active ingredient in Isofra is the bactericidal substance framycetin. Framycetin is a derivative of the aminoglycoside antibiotic neomycin. It is able to destructively affect pathogens by damaging their cell membrane, as well as disrupting the metabolic process that occurs inside the cell. Pathogenic microorganisms such as penicillin-resistant staphylococci, gram-positive streptococci, gram-negative salmonella, shigella, and klebsiella are sensitive to the drug.
Treponema, anaerobes, and some strains of streptococci are immune to framycetin. Resistance in pathogens to this drug is formed extremely slowly.
This is confirmed by the instruction for Isofra spray. We will consider reviews below.
Release Forms
The medication "Isofra", designed to combat the common cold and some infections of the ENT organs, is produced by the manufacturer in only one pharmacological form - in the form of a spray. The medicine is packaged in 15 ml plastic bottles, equipped with a special dispenser for spraying funds. Each bottle is additionally packed in a cardboard box.
Each milliliter of Isofra contains 12.5 mg of the main component, framycetin. In addition, the nasal spray contains some auxiliary substances: matylparaben, sodium citrate, sodium chloride, citric acid, distilled water.
According to reviews, the spray "Isofra" is quite affordable. On average, the cost of one package in Russian pharmacies fluctuates at the level of 300 rubles.
Most of the funds used to combat the common cold are effective due to the ability to narrow the blood vessels, thereby reducing the production of mucus and preventing nasal congestion. "Isofra", in turn, does not have a vasoconstrictor in its composition, respectively, does not have a vasoconstrictor effect and is intended to eliminate the cause of the common cold - infection.
If the patient is shown to use a therapeutic spray, the doctor must fill out a prescription form, otherwise it will not be possible to purchase the drug at the pharmacy.
Reviews and analogues of "Isofra" are of interest to many.
Indications for use
Quite often colds of a viral nature are complicated by the parallel attachment of bacterial infections. Similar situations are typical for children, since the anatomy of their respiratory system promotes the penetration of pathogenic microorganisms. Doctors prescribe a nasal spray if there are green mucous purulent discharge from the nose. The reason for such discharge may be:
- Nasopharyngitis (runny nose with bacterial etymology).
- The chronic form of rhinitis.
- Sinusitis (inflammation in the paranasal sinuses), if there is no curvature of the nasal septum.
In adult patients, Isofra is often used to treat sinusitis, chronic or acute rhinitis. Another form of medicine containing a larger amount of active substance does not exist. Therefore, adults should simply spray the drug in the nose more often than small patients.
Contraindications
Like any medical product, the use of Isofra should not be given to patients who have an individual sensitivity to any component that is part of the drug. In addition, experts do not recommend the use of nasal spray for women who are at any stage of pregnancy. Do not use the drug during lactation.
Drug dosage
The action of the drug is local. That is, the active component does not penetrate into the systemic circulation, but acts directly on the mucous membranes of the respiratory system. It is this that determines the possibility of using this antibiotic in the field of pediatrics - there is no harmful effect on the child's body. There are no cases of overdose or negative interactions with other drugs used orally or parenterally for the same reason.
Reviews about Isofra for children will be presented at the end of the article.
For small patients, medication is prescribed most often if there is a thick green mucous discharge, which indicates an attached infection of a bacterial origin. In such cases, it is necessary to rinse the nose of the child before injecting the drug. You can use simple saline or special salt solutions, which are presented in the pharmacy. The washing procedure will allow more efficient cleaning of the mucous membranes and enhance the therapeutic effect of the nasal antibiotic.
This is indicated in the instructions for Isofra. According to reviews, it is completely safe for children. But you still need to be careful.
When injecting the vial with the drug must be kept upright. In each nasal passage, one injection is required. This should be done no more than three times a day. In general, the duration of treatment should not exceed one week. Most often, the unpleasant symptoms of the disease with the use of Isofra disappear after three days. If the effectiveness of the use of the drug is not observed after a week, it is necessary to stop its use and consult with your doctor about the replacement of the drug.
In the treatment of adult patients, the injection pattern is similar to that of children. It is also recommended to carry out a preliminary washing of the nasal cavity in order to cleanse the mucous membranes. Injections are made one at a time in each nasal passage, the duration of use is no more than a week. The only difference in treatment regimens for children and adults is that the latter need to produce up to 6 injections per day.
Side effects
With local use, recommended by the instructions for the drug, the active component does not penetrate into the systemic circulation. Accordingly, there is no systemic effect on the body, side effects characteristic of antibiotic therapy (such as dyspepsia, dysbiosis, impaired activity of the NS) do not develop. According to reviews of Isofra, in rare cases only local allergic manifestations, such as redness or burning, can occur.
Use by pregnant women, as well as during lactation
Large-scale clinical studies on the penetration of framycetin into breast milk and its effect on the fetus have not been conducted. Thus, medicine does not have reliable data. Despite the fact that the antibiotic does not penetrate the blood and is theoretically not dangerous, the manufacturer in the instructions for use does not recommend the use of the drug throughout the entire period of pregnancy, as well as during the entire period of breastfeeding.
This is stated in the instructions for use. Reviews about "Isofra" for children and adults are mostly positive.
Alcohol Compatibility
Medicines aimed at combating infections and intended for local use do not enter the bloodstream and, therefore, do not mix with ethanol. This allows us to conclude that it is possible to combine treatment with alcohol, but it will be erroneous. Alcoholic beverages contribute to the expansion of blood vessels, causing a strong rush of blood to the tissues. As a result, mucus secretion increases, swelling is aggravated, the general condition of the patient worsens. Among other things, alcohol is extremely negative for a body weakened by a disease.
We reviewed the instructions for use with Isofra. Reviews and analogues are presented below.
Analogs
French nasal antibiotic is quite expensive - a small bottle of 15 ml will cost the consumer 300 rubles. Despite the fact that one package is enough for the entire course of treatment, situations often arise when the patient needs to replace the drug. Isofra does not have structural analogues based on framycetin. Therefore, in order to choose a replacement, you should contact your doctor. Most often, the following drugs are recommended:
- "Protargol." It is a 2% solution of the active component. Prepare this drug in a pharmacy with a prescription. The cost of such a medication does not exceed 100 rubles. Quite often, pharmacists propose replacing Protargol with a factory Sialor, which costs about the same as Isofra.
- Okomistin. This drug, in essence, is eye drops, but can be used in otorhinolaryngology. The average cost per 10 ml bottle of the drug ranges at 130 rubles.
- "Collargol." It is an antiseptic medication with a bactericidal effect. Prepare this drug directly in the pharmacy. Its average cost is up to 15 rubles.
- Miramistin. It is an antiseptic in the form of a spray. The average price in pharmacies is 200 rubles per bottle of 50 ml.
- Chlorophyllipt oil solution. Effective in dealing with the common cold, if used together with systemic drugs. The approximate cost of 140 rubles per 20 ml.
Other medications are also available that are similar to Isofra. A drug such as Rinofluimucil is very popular. However, it is important to consider that it is not an antibiotic and can only deal with symptoms, and not with the cause of the disease. That is, "Rinofluimucil" has a decongestant, anti-inflammatory and vasoconstrictive effect, like many other similar drugs.
He also has a more extensive list of contraindications, and there are much more adverse reactions against the background of its use. Some of them are associated with cardiac arrhythmias. If we compare "Rinofluimucil" with "Isofra", then the first should not be prescribed to children.
Isofra and Polydex
Both drugs have the form of a spray for nasal use, their cost is about the same, the effect is local, the indications for use are identical. The main difference between drugs is the qualitative and quantitative composition. It is he who determines the list of contraindications to the use of each and drugs.
The composition of the "Polydex" combines two antimicrobial substances - polymyxin and neomycin. Thanks to this combination, the spectrum of activity of the drug is significantly expanded. Also in the composition is phenylephrine and dexamethasone, which provide anti-inflammatory and vasoconstrictor effects. In general, Polydex is more effective than Isofra, but it is not recommended to prescribe it to persons with impaired renal function and children under 30 months of age.
According to reviews, Isofre for the nose people trust more.
Isofra and Derinat
Derinat is an immunostimulating drug effective for ENT infections. It can be prescribed to children from birth.
The main active substance in its composition is sodium deoxyribonucleate. The substance is effective when used in combination with other medicines, does not directly affect pathogens. Accordingly, the possibility and advisability of replacing Isofra with Derinat should be determined by an ENT specialist or pediatrician.
Reviews about Isofra
Most reviews about the drug are positive. Patients report that the drug is very effective in the initial stages of a disease caused by bacteria. If the disease has a viral etiology, then the drops will be useless. Many patients managed to get rid of a runny nose in just a couple of days, but they note that after treatment they had to deal with the restoration of microflora in the nasopharynx.
What other reviews about Isofra are there?
High efficacy of the drug is noted when using it against sinusitis. Already on the third day comes relief. If it is absent, then it is better to abandon the use of this antibiotic. Some patients note that they managed to completely cure sinusitis, which for a long time was in a chronic form.
According to reviews, Isofra drops are effective in treating bacterial diseases in children. It is important to remember that a doctor should prescribe a nasal antibiotic exclusively for children over 12 months of age. Parents of young patients indicate that the drug is highly effective against sinusitis, sinusitis, adenoids, rhinitis. If you use the medicine as prescribed by your doctor, do not self-medicate, follow the recommendations in the instructions, then the risk of side effects is extremely low.
The article presented instructions and reviews for Isofra.