Nowadays, quite often people are faced with the problem of pain in the joints, back or spine. In connection with sedentary work, many patients have long been familiar with the diagnosis of osteochondrosis. Muscle and joint pain is often experienced even by small children during accelerated growth of the body. The options are different, but in many cases, doctors prescribe the well-known pain medication Metindol-retard.
Description
This drug is a non-steroidal anti-inflammatory drug. Indomethacin is the active substance of this medicine. "Metindol" has an analgesic and anti-inflammatory effect. Also, this drug is able to have an antiplatelet effect.
Release form and composition
This medicine is available in tablet form. They can be white or yellowish white. The surface of the tablet is flat, the edge is cut off. In a blister pack of 25 tablets, the blister is in a cardboard bundle. The main active ingredient is indomethacin. The tablet also contains additional substances such as potato starch, microcrystalline cellulose, magnesium stearate, talc. In addition, this drug is available in the form of dragees, gel, capsules, ointments, suppositories and ready-made solution.
pharmachologic effect
The drug has anti-inflammatory, analgesic, desensitizing and antipyretic effects. Also, the pharmacological actions of this medication include the elimination of pain and swelling of the joints, the elimination of swelling around the joints and morning stiffness. In addition, Metindol fights erythema and contributes to a significant expansion of the range of motion.
Indications for use
The drug has a strong analgesic effect, therefore, it is most often prescribed for pathologies of the musculoskeletal system, as well as for pain syndrome of various origins. The drug has the property of stopping the pain syndrome (conditions such as toothache, lumbago, pain after surgery and traumatic injuries, headache, myalgia, sciatica, neuralgia).
"Metindol Retard" is often prescribed for the following diseases: neuralgic amyotrophy, arthritis, Paget's disease, ankylosing spondylitis, rheumatism, gout. Also, the drug is indicated for inflammatory and infectious diseases, such as pharyngitis, otitis media, tonsillitis. Due to the fact that the medication has a good analgesic effect, it is also prescribed for the treatment of pericarditis, secondary hyperaldosteronism, algomenorrhea, adnexitis, and the inflammatory process in the pelvis.
During traumatic injuries of muscles, joints or tendons, Metindol is prescribed as an ointment or gel. Also, an ointment or gel can be prescribed as anti-inflammatory for joints, for example, with radiculitis, myalgia, lumbago, osteochondrosis, arthritis. The exception is the degenerative pathology of the hip and small intervertebral joints.
Contraindications
"Metindol" is contraindicated in congenital heart disease, such as atresia of the pulmonary artery or severe aortic coarctation. Also, this drug is not prescribed for peptic ulcers of the digestive tract, for gastric bleeding, cirrhosis, ulcerative colitis, aspirin triad, as well as for violation of color or visual perception.
Contraindications include arterial hypertension, asthma, heart and liver failure, pathology of the optic nerve, swelling, impaired blood coagulation and blood formation (leukopenia, anemia). Also, the drug is contraindicated in patients with reduced auditory perception and pathology of the vestibular apparatus. Pregnancy and lactation are also contraindications.
With hemorrhoids and proctitis, the administration of a drug in a rectal form is contraindicated. A gel or ointment is not prohibited, while they also have a strong analgesic effect. For children and the elderly, as well as patients with thrombocytopenia and epilepsy, the drug is not prohibited, but its use should be very careful. The drug in the form of a gel or ointment is prohibited for babies up to 1 year old.
Side effect
"Metindol" is a good painkiller, but side effects such as nausea, vomiting, anorexia, diarrhea or constipation, abdominal pain and even gastrointestinal perforation can be observed while taking this drug. This applies to the digestive system. On the part of the nervous system, headache and dizziness, a feeling of tiredness or depression, mental disorders and sleep disturbance can be observed. On the part of the cardiovascular system, edema, chest pain, tachycardia, arrhythmia, and increased blood pressure can occur. Allergic reactions occur less frequently. These include erythema nodosum, urticaria, pruritus, skin rash, and dermatitis.
Regarding other systems of the body, rarely, but there may be hearing or vision impairment, impaired renal function, increased sweating, vaginal or nasal bleeding, tension or enlargement of the mammary glands. With rectal administration of Metindol Retard, tenesmus, irritation on the mucous membrane of the rectum may occur, and chronic colitis may also aggravate. With external use of the drug, itching, rash or redness of the skin is possible.
Application
The drug can be used in three ways (externally, orally, rectally). At the first stage of treatment, adults are prescribed 25 mg of indomethacin about 2-3 times a day. The medicine should be consumed after a meal with milk. If the drug is not effective at this dosage, the dosage is increased. The medicine should be continued to be drunk 2-3 times a day, but the daily norm in this case is 150 mg. It should be borne in mind that the maximum daily dose of the drug is 200 mg. After the desired effect is achieved, the amount of medication should be gradually reduced. The course of treatment is 30 days. If therapy has a long period, the maximum dose per day is 75 mg.
Rectally, the drug should be used before bedtime, after a complete cleansing of the intestine. Ointment or gel is used only externally, 2-4 times a day. The gel should be applied to the affected area of the joints. The adult maximum dose of ointment per day is 15 cm (the length of the strip from the tube), and the children's dose is half as much (7.5 cm) of the gel or ointment.
Overdose
An overdose of Metindol Retard is manifested by nausea, vomiting, severe headache or dizziness, memory impairment and disorientation in time can be observed. In a particularly severe case, paresthesia, convulsions may appear, and numbness of the limbs may also be observed . In case of an overdose, immediate removal of the drug from the body is required.
special instructions
Elderly people as well
patients with kidney and liver diseases should use the drug with extreme caution. Also, caution should be used in patients with arterial hypertension and heart failure.
Many experts say that Metindol Retard is the best anti-inflammatory drug, but during treatment it is necessary to systematically monitor kidney and liver function. The use of this drug simultaneously with acetylsalicylic acid is not recommended. Do not apply ointment or gel to the wound skin surface. It is advisable to avoid getting the drug in the eyes. In case of contact, rinse thoroughly with water.
It should be borne in mind that the drug negatively affects the management of vehicles and other mechanisms, therefore, during the treatment period, activities that require an increased concentration of attention should be avoided.
Drug Interactions
The simultaneous use of indomethacin can reduce the effect of beta-blockers and saluretics, as well as increase the effect of indirect anticoagulants. Using indomethacin together with diflunisal can cause severe gastric bleeding. If you apply this drug with probenecid, the concentration of indomethacin in the blood plasma may increase. If you use "Metindol" with digoxin, there is a chance of an increase in the level of digoxin in the blood plasma.
"Metindol Retard." Drug price
The price of the drug depends on the manufacturer, as well as on the form of release. The cost of this tool in tablets ranges from 100 to 150 rubles per blister.
Storage conditions
Keep this medication in a dark place. The temperature should not be lower than 15 and not higher than 25 degrees. Shelf life is 60 months.
Analogs
Very often, patients in pharmacies ask for analogues of a particular medicine. Painkillers can be found at any pharmacy. Given that Metindol is available on prescription, you can ask for its analogues. This medicine belongs to the group of medicines that can remove pain in joints and muscles. This group also includes such drugs as Meloxicam, Diclonac, Pfizer. Also, Metindol is part of a group of drugs aimed at treating diseases of the spine and joints. This group also includes such drugs: “Heparoid Lechiva”, “Ibuprofen”, “Ketorol”. In addition, Metindol Retard belongs to the group of non-steroidal anti-inflammatory drugs. In this case, "Indomethacin-Acre", "Paracetamol" may be an analogue.
Reviews
Basically, the reviews of both patients and doctors about this drug are positive. When patients come to a specialist, they are asked to prescribe any means (tablets or ointments), but so that the drugs are painkillers. The price is also important, as many cannot afford expensive drugs. "Metindol" is a relatively inexpensive and at the same time potent means. Therefore, doctors recommend it.
It should be borne in mind that this drug has many side effects, so you need to take it with caution, be sure to consult a specialist (especially if there are any additional health problems). In addition, treatment should be carried out under the supervision of a doctor, you should not prescribe this drug for yourself (as, however, others).