The name "Anavenol" is a commercial one, which is assigned to the manufacturer, which began to deliver this therapeutic drug to the market for the first time. It is impossible to provide a name by INN (international non-proprietary name) in this case, because the medication consists of a composition of a pair of active elements. Detailed instructions for the use of "Anavenol", price, and reviews (in general, pleasant) - all together make the medicine often prescribed by doctors. After all, it is rarely possible to buy a product at an affordable price and with good reviews.
It can be stated that "Anavenol" is considered to be an artificially created, combined substance consisting of natural, natural ingredients, purified and selected in the optimal dosage.
Pharmacology
According to the instructions for use, "Anavenol" is a combined medication. It shows a venotonic effect, reduces the permeability of the vascular wall, improves microcirculation.
The substance dihydroergocristine, which is part of the composition, is considered to be a semi-synthetic derivative from the ergot alkaloids category, has an alpha-adrenergic blocking effect, expands arterioles, slightly increases the tone of veins, and thereby contributes to the improvement of peripheral circulation. Rutoside and esculin exhibit vasoprotective and antiexudative effects.
When to apply?
As indicated in the instructions for use, "Anavenol" is used for diseases of peripheral veins and the development of venous insufficiency syndrome, with the following symptoms:
- varicose veins and pre-varicose veins diagnosed by ultrasound, while more correctly prescribed in the initial stages;
- venous peripheral thrombosis;
- post-thrombotic conditions;
- getting rid of thrombophlebitis;
- trophic ulcers of the extremities - much more effective as part of complex therapy;
- soft tissue injuries, post-traumatic conditions;
- limb immobilization (plaster bandages, longs, stretching after the procedure).
Prophylactic use
The usefulness of the drug in the effective prevention of edema. Since "Anavenol" includes natural components, it is not forbidden to use it for preventive purposes, if ultrasound does not show signs of damage to even small venous vessels, but there are medical signs of "pre-disease":
- heaviness in the legs;
- spasms of the calf muscles;
- evening swelling on the legs.
Heavy use
Also, special working conditions and physiological stress are considered indications for preventive use:
- standing / sedentary activity;
- prolonged stay on the legs;
- active physical activity in the gym.
Conditions under which the product is not used
Unconditional honey. a contraindication is bleeding, hemophilia, diseases associated with a decrease in blood coagulation.
Performance has not been studied in children under 15 years of age.
Separate hypersensitivity to ergot alkaloids, horse chestnut and mint concentrates is a contraindication.
Relative contraindications (that is, a medicine is permissible to use if the intended utility obviously exceeds the risk of harm from consumption) are:
- chronic renal and liver failure;
- heart failure, with the formation of "edema";
- slow heart rate, especially if the disease occurs simultaneously with arterial hypotension (low blood pressure, less than 110/65 millimeters of mercury);
- working conditions requiring concentration, organization and speed of reaction: when working with moving machines and devices (machine operators, drivers, pilots, train drivers), as well as during high-altitude work.
Compatibility with alcoholic beverages of a pharmaceutical preparation has not been investigated.
Dosage
General tips for using the drug - taking without chewing, drinking with the necessary amount of liquid. In the case of the appointment of a medicine in drops, they are pre-diluted in water.
At the beginning of the course of therapy, the purpose is as follows: doubling the portion for the first 7 days is taken, the method of use is two pills three times a day, then there is a switch to the maintenance dose of the tablet three times a day.
If "Anavenol" is prescribed in drops, then twenty drops are prescribed 4 times a day in the first week, from the beginning of the 2nd week - the same portion for one use, however, the frequency of administration is reduced to two to three times a day. The dose of drops is adjusted by shaking the bottle.
How long are allowed to take the drug in capsules? According to statistics, the average duration of a course is from a month to 3. The interval between courses is comparable in time with their duration.
Side effects
The incidence of secondary effects is not too high. Similar manifestations belong to them, such as:
- Regular headaches and dizziness.
- Fatigue.
- Hyperemia of the mucous layers (the most formed congestion is hyperemia of the mucous layer of the nasal cavity).
- Phenomena of gastric and intestinal dyspepsia (nausea, infrequent vomiting or diarrhea).
- Local allergic interactions (dermatological irritation, nettle fever, rash).
- The manifestation of high bleeding and bleeding is menorrhagia.
- Infrequent uterine bleeding.
- Inhibition, lethargy, disorder of coordination of movement and speed of reaction.
In case of occurrence of data or other signs, the intake of the substance is postponed and urgent medical consultation is necessary. The development of side effects was studied in 10 thousand subjects using a medication.
Interactions with other pharmaceuticals
An increase in effects (which means an increase in the frequency of development of secondary signs) stimulate:
- tetracycline antibiotics;
- vasodilators (vasodilating substances and individual antispasmodics of myotropic effects).
Drugs that have an alpha-blocking effect. The weakening of the results of "Anavenol" occurs due to competitive inhibition of adrenergic receptors. These are substances that may include adrenaline, as well as drops from rhinitis.
Separate danger can form hypotensive substances. Together with Anavenol, mutual potentiation of the results is formed. As a result, a collaptoid state, fainting may form.
With a predisposition to low blood pressure or during the selection of antihypertensive drugs, if sudden pressure surges are likely, it is more correct not to start taking the substance, but wait a week or two to normalize the condition.
It is imperative to inform the phlebologist not only about their own allergic reactions, but about absolutely all the substances taken today and their doses, so as not to stop the cure.
special instructions
Since no deep studies have been conducted, the use of the substance is not recommended at the very beginning of pregnancy, namely until twelve weeks.
In the next 2 trimesters, a substance is likely to be taken only if its usefulness will undoubtedly exceed the risk of secondary effects. At every opportunity, prophylaxis in women in position should be carried out using non-medicinal methods, for example, correctly wearing special compression knitwear.
Also, a therapeutic physical culture, long walks, swimming, and water aerobics are considered a significant component of prevention and cure.
In addition, the ability of an invasion of a substance from mother’s blood into breast milk has been poorly studied, for this reason, if possible, you should beware of using the substance during lactation.
It is also necessary to take into account the ability of a substance to dull the reaction, impair the ability to drive a vehicle.
Analogs
There are many drugs available that are analogues of Anavenol and have a similar effect.
"Venoplant" - a drug that reduces the level of capillary permeability, has anti-inflammatory, as well as venotonic and decongestant effect. It has an inhibitory effect on the activation of lysosomal enzymes that promote proteoglycan cleavage. Strengthens the tone of the venous wall, prevents blood stasis, and also reduces capillary fragility. Slows down inflammatory processes.
Application: 1 tablet twice daily, orally, washed down with water. Perhaps the development of side effects in the form of allergic reactions. Contraindications: hypersensitivity to the components (according to the instructions for use of the analogue of "Anavenol"). The price and reviews of the drug say that this is an affordable tool and quite effective.
"Reparil-gel" is a combined anti-inflammatory drug. It is applied locally. The substance escin, which is part of the composition, has a capillaroprotective effect, helps to reduce swelling, tissue tension and pain. Diethylamine salicylate, also contained in the drug, has an analgesic and anti-inflammatory effect. Due to menthol, a local cooling effect is achieved. Contraindications:
- wounds;
- preliminary irradiation of mucous membranes and skin.
Application: the gel is applied, evenly distributing on the surface of the damaged area. It does not require rubbing into the skin. Perhaps a rare development of side effects in the form of allergic reactions, such as itching, rash.
"Ascorutin" is a drug whose action is aimed at filling the deficiency of vitamins C and P. The active substance rutin with ascorbic acid has an effect during redox processes. Rutin creates an antioxidant effect, helps to stop oxidation and preserves ascorbic acid in the cells of tissues. Helps strengthen the walls of blood vessels by inhibiting the activity of hyaluronidase and due to the formation of intercellular substance. Reduces fragility of capillaries and their level of permeability. Contraindications:
- hypersensitivity;
- with caution with increased blood coagulability and a tendency to thrombosis;
- under the supervision of a doctor for diabetes.
Application: 1 tablet 3 times a day, before or after eating. The duration of the course is set depending on the disease and the effectiveness of the treatment. Side effects are allergies.
Reviews
According to reviews and instructions for use, "Anavenol" in tablets, the price of which is 200 rubles, is necessary for people whose blood circulation is impaired, vein thrombosis develops. This unique drug helps in treatment due to its composition:
- dihydroergocristine increases the elasticity of veins, expands small arteries;
- esculin helps reduce vascular permeability;
- rutoside acts on them as an anti-inflammatory and decongestant.
"Anavenol" does not allow blood to stagnate in small vessels of the lower extremities, it fights with varicose veins and with the syndrome of "tired legs". It helps to establish blood circulation in the legs if a person has been without movement for a long time or has suffered a complex injury. Taking the medicine depends on the severity of the disease. The course of necessary therapy is prescribed by the doctor, usually it lasts 30 days.