The drug "Katadolon" is a drug that is used to relieve symptoms of pain. Pain can occur with neuralgia, neuritis, degenerative joint diseases, cancer, migraine, muscle spasms of the musculoskeletal system, bruises, chemical, thermal burns. The medicine belongs to non-opioid analgesics of central action.
The drug "Katadolon." Instructions for use: dosage form, composition
The drug substance is available in the form of capsules, which have a brown-orange color. They contain white powder, which is odorless. "Katadolon" - tablets are much less common, as they have a slightly reduced pharmacological effectiveness, an increased period of clinical action.
The main active substance of the drug is flupirtine maleate. Auxiliary components include calcium phosphate dihydrate , capovidone, magnesium stearate, red iron oxide , titanium dioxide, purified water, sodium lauryl sulfate, gelatin.
Capsules "Katadolon". Instructions for use: pharmacokinetics, pharmacodynamics
The active substance of the drug after oral administration is rapidly absorbed (bioavailability reaches 90%). Flupirtine is metabolized in the liver tissue. As a result of chemical transformations, urethane structures, metabolites M1, M2 are formed. Most of the drug is excreted by the kidneys. The elimination half-life reaches seven hours, which is the most optimal value for analgesics. When the drug is administered to elderly patients, an increase in this indicator is observed.
The active substance of the drug is the prototype of a class of non-selective substances that activate specific potassium channels. The active substance has analgesic, muscle relaxant, neuroprotective effects.
The drug "Katadolon." Instructions for use: dosage
The dose of the drug is selected depending on the individual sensitivity of the patient, the severity of the pain symptom. It is necessary to take one capsule four times a day, drinking them with plenty of water. With severe, intense pain, the dose may increase to two capsules per dose. It should be taken three times during the day. For elderly patients, this value must be reduced due to a decrease in metabolic functions. The daily dose of the drug should not be higher than six capsules, otherwise an overdose will occur. In fairly rare cases, the capsule can be opened and taken through a probe.
The drug "Katadolon." Instructions for use: side effects, contraindications
Among the side effects of the drug, weakness, dizziness, nausea, vomiting, dizziness, diarrhea, abdominal pain, flatulence, anorexia, depression, sleep disturbances, tremors, confusion, sweating, the appearance of allergic reactions (itching, urticaria, hyperthermia) are distinguished. In very rare cases, hepatitis can occur, which is accompanied by jaundice with the development of symptoms of cholestasis. When the first such symptoms appear, you should stop using the Katadolon pharmaceutical. A description of all possible indications, contraindications, drug interactions is in the instructions. Therefore, when buying a medicine, you must carefully study it.
The following contraindications to the use of the drug are distinguished: cirrhosis of the liver, liver failure, accompanied by phenomena of encephalopathy, muscle asthenia, cholestasis, chronic alcoholism, lactation, pregnancy, hypersensitivity to individual components.