A specific reaction of the body's defense system to food, medicine and cosmetics, as well as substances of animal and plant origin, is called allergy.
To eliminate such conditions, a huge number of medicines are used, but the most effective way is hormonal injections from allergies, which help for a long time to forget about an unpleasant symptom.
Why exactly injections?
The introduction of drugs through the blood supply system has a number of positive aspects:
- Good digestibility of the drug.
- Fast and powerful therapeutic effect.
- The possibility of use in patients who have problems with the stomach and intestines.
In addition to the advantages of such treatment, there are also negative aspects:
- For injections, certain skills or the help of a medical specialist are required.
- The risk of side effects due to high bioavailability and the effect of the drug on the whole body increases.
- Unsuitable for frequent use.
- Medications are inconvenient in transportation and use.
- If the rules of asepsis are not observed, suppuration may occur at the injection site.
What drugs are used for allergies?
Hormonal injections from allergic manifestations, as a rule, are divided into several therapeutic groups:
- Glucocorticosteroid preparations.
- Desensitizing agents.
- Antihistamines for injection.
- Immunobiological medicines.
Desensitizing agents
These are drugs that prevent or weaken the clinical signs of increased body sensitivity to various foreign components, provoking a state of hypersensitivity.
These include calcium salts:
When allergies are treated with hormonal injections. The antiallergic effect of the medication is due to the combination of histamine and inhibition of the sensitivity of the body's cells to allergy mediators. The use of calcium helps to eliminate allergic manifestations - rash, itching, hyperemia, edema. This category of drugs belongs to additional methods of therapy. The duration of treatment varies from five to ten procedures.
Calcium chloride
Salt injections are contraindicated in case of excessive concentration of calcium ions in the blood, as well as with thrombosis and atherosclerosis. When using the drug, you can feel the growing feeling of heat, for which calcium chloride is also called "hot injection".
Given that the solution affects muscle contraction and transmission of nerve impulses, a slowdown in the rhythm of heart contractions and ventricular fibrillation (chaotic contractions of myocardial tissue) may appear. Such injections increase the pharmacological effect of antihistamines.
The medicine must be administered intravenously in combination with a five percent glucose solution or saline. It is important to note that injections can only be performed by a doctor who has certain knowledge and skills of intravenous injection - otherwise tissue necrosis may form. The price of the drug is 70 rubles.
Calcium gluconate
The drug is chemically unstable - if after opening the package in the solution there is sediment or flakes, the drug must be disposed of immediately. The solution is injected directly into a vein or muscle, so the medication can be used at home.
The prohibitions on the use of the drug are exactly the same as the previous medicine. It is worth paying attention that calcium gluconate is not recommended to be combined in the same syringe with other drugs. The dosage of the solution directly depends on the age of the patient and is selected purely individually. It is necessary to put one injection per day. In rare situations, an injection is done after a day. The cost of the drug varies from 10 to 190 rubles.
Histamine receptor blockers
Medicines, the main influence of which is focused on the elimination of acid-dependent diseases of the gastrointestinal tract.
It is the histamine receptor blockers that can be considered real anti-allergic hormonal injections - the spectrum of action is due to the suppression of histamine-sensitive receptors. In addition, they reduce the production of histamine, which is involved in the onset of allergies.
After the injection, the onset of signs of the disease is reduced. The number of injections is small and is represented by first-generation drugs. A distinctive feature of this group is a calming effect, which can be manifested by lethargy, drowsiness, as well as inhibition of psychomotor reactions. Therefore, drivers and people whose duties require increased attention, it is necessary to limit such a load. In addition, the drugs narrow the lumen of the vessels and organs of the urinary tract, stomach. Such an effect is important to consider for patients suffering from:
- Violation of urination of various etiologies.
- Diseases of the heart and blood vessels.
- Hyperthyroidism.
It is important to remember that when testing for allergens, the use of antihistamines is canceled three days before the study. With the introduction of other medicines, you should thoroughly familiarize yourself with the instructions for use for compatibility with an antiallergic agent.
Diphenhydramine
The very first representative of antihistamine drugs. The active substance is diphenhydramine. It is additionally used for vomiting. It has no age restrictions.
The use of the drug is contraindicated in case of increased sensitivity to the main and auxiliary substances. "Diphenhydramine" is available on prescription by a medical specialist. The cost of the drug is 50 rubles. What hormonal injections can I put?
Tavegil
Clemastine-based medication. The drug has a pronounced antipruritic effect, so its use is justified in patients with skin diseases. "Tavegil" is forbidden to use in the following conditions:
- Children under one year old.
- With diseases of the lower respiratory tract, as well as bronchial asthma.
- With individual intolerance.
- Lactation and pregnancy.
Single dosing - one ampoule. Both intravenous and intramuscular use of the drug are allowed. The price of the drug varies from 150 to 350 rubles.
"Suprastin"
The drug represents a therapeutic group of drugs that are blockers of H-histamine receptors. It has an antiallergenic effect and is used to reduce the severity of allergies. The main active substance of the drug is considered to be chloropyramine. Daily dosing - no more than two ampoules. Contraindications to the introduction of the drug are identical to other antihistamines. The cost of the drug varies from 100 to 200 rubles.
Glucocorticosteroids
To eliminate allergies, steroid hormones from a subclass of corticosteroids produced by the adrenal cortex can be prescribed. The use of these drugs should be justified.
List of hormonal injections:
- Prednisone.
- "Dexamethasone".
- Diprospan.
They are not recommended for use without the appointment of a medical specialist, since self-medication can cause serious adverse reactions:
- Hormone deficiency.
- Menstrual irregularities.
- Deterioration in the absorption and utilization of glucose.
- Diabetes.
- Hyperglycemia.
- Cushing's Syndrome.
- Sodium ion delay.
- Swelling.
- Hyperglycemia.
- Weight gain.
- Alkalosis.
Changes in the hormonal background can aggravate the situation - provoke the occurrence of acne and striae, a violation of pigmentation, increased sweating, and worsening recovery processes. And this list is not complete. Here are the most serious consequences of hormonal injections.
The spectrum of anti-allergic effects is due to the stimulation of specific processes that appear after the interaction of hormones with specific cell receptors and incorporation into deoxyribonucleic acid. This can lead to an imbalance of proteins in the body:
- The synthesis of allergy mediators is reduced.
- The immune response to the allergen is suppressed (a complex multicomponent, cooperative reaction of the body's immune system, induced by an antigen already recognized as foreign, and aimed at its elimination).
The only prohibition for short courses of therapy with hormonal injections is individual intolerance. In situations where prolonged treatment is necessary, the list of contraindications is somewhat wider.
The drug is administered intramuscularly in pure form or with an infusion solution. Dosage is determined by the doctor purely individually and depends on the general condition of the patient.
Prednisolone
"Prednisolone" is the name of a hormonal injection that has an anti-allergic effect that can persist for another day. The use of the drug is prohibited during lactation. Women in the "position" is also not recommended to use "Prednisone" in the first three months. The price of the drug varies from 50 to 110 rubles.
Dexamethasone
The most reactive drug from the group of corticosteroids. The action develops immediately after using the solution. Injections are indicated for the elimination of chronic diseases.
The most popular hormonal drug for allergies. Moreover, it has a negative effect on the hormonal background and the whole organism. In the "interesting position" special care is necessary, because this drug slows down the intrauterine development of the unborn baby. The cost of the drug varies from 40 to 180 rubles.
Diprospan
Long-acting medication - signs of allergic manifestations are eliminated for a long time immediately after use. The solution is applied strictly intramuscularly, after which the medicine slowly dissolves and is absorbed into the blood within two to three weeks. The price of the drug ranges from 180 to 210 rubles.
Pros and cons of hormonal injection treatment
Patients suffering from allergic manifestations often wonder about the benefits and harms of hormonal injections from allergies. They can conditionally be divided into two large groups.
These are hormonal injections and non-hormonal. There are many different opinions about their effectiveness and safety, but in some countries injections are extremely rare, in very difficult situations or in life-threatening conditions.
First and second generation drugs can provoke a large number of adverse reactions, while modern drugs can not actually do this.
First-generation medicines include Diazolin, Suprastin and Diphenhydramine. They have a short-lived effect, and in rare cases can disrupt the functioning of the human vascular system.
Second-generation drugs no longer have a detrimental effect on capillaries, and their effect can persist for almost a day. These drugs include "Loratadine" and "Astemazin."
Among the main disadvantages of this treatment, its duration is distinguished. A full course of therapy can take up to several years. Discontinuation of the drug may provoke a pathological process with new complications after hormonal injections. Also, the negative side of the drugs can be called their lack of control.