Yeast-like fungi of the genus Candida are present in the body of many people, but with the proper functioning of the immune system they are not particularly dangerous. But once a person gets sick, even acute respiratory infections, as these insidious microorganisms begin to actively increase the number of their colonies, affecting the skin and mucous membranes. Everyone who has encountered a similar problem is well aware of the Nystatin drug. The analogs of this medication occupy a rather large sector of the assortment of pharmacies, and it is these drugs that will be discussed later.
Pharmacological characteristics of the drug "Nystatin"
Before you begin to study the substitutes for this drug, you should familiarize yourself with its pharmacological properties. This medication belongs to the group of polyenes. The antifungal agent "Nystatin" comes into contact with sterols at the level of the cell membrane of pathogenic microorganisms and violates their penetration. Due to this effect, the main components exit the cell, destroying it.
Like the Nystatin agent, the drug’s analogues are active against Candida yeast-like fungi.
Release form, indications, dosage
To date, the medication is available in three main forms. The first - tablets, contain 250 thousand units and 500 thousand units. They are prescribed for candidiasis of the internal organs and mucous membranes. Quite often, this medication in tablet form is recommended for prophylactic use in people with weakened immunity after prolonged use of antibiotics. Adults are prescribed 500 thousand units 4-8 times a day.
The second form of the drug is ointment. It is used for candidiasis of the epidermis. Ointment is applied to the affected area 2 times a day.
As for the third form of the drug, these are rectal and vaginal suppositories. The former are prescribed for candidiasis of the lower intestines and with the aim of prevention in the pre- and postoperative period. Doctors recommend using vaginal suppositories for their patients with vaginal candidiasis. Both the first and second suppositories are prescribed one twice a day.
The duration of drug therapy is 10-14 days.
Contraindications
If the doctor prescribed Nystatin, it’s pointless to look for analogues. After all, this domestic drug is the most affordable. However, it has a list of contraindications that should be considered before use. So, people with pancreatitis, peptic ulcer of the duodenum and stomach should refuse to take the drug. Do not use the medication for various violations of the liver and hypersensitivity to any of the components of the drug. During pregnancy and for the treatment of candidiasis in children up to a year, the replacement of Nystatin will also be required. Analogues in all of the above cases should be selected exclusively by the doctor.
Drug Reviews
To say that the drug "Nystatin" has only positive reviews, of course, is impossible. After all, like any other medication, it can cause adverse reactions of the body. So, taking a tablet form of the drug is sometimes the cause of nausea, diarrhea and vomiting, and in some cases a skin rash. Any of these side effects, of course, causes a certain discomfort, as a result - negative reviews about the medicine. However, most people who used the drug respond positively to it and are very satisfied with the result of treatment.
It is worth noting that, like Nystatin, analogues are also quite effective in candidiasis.
Analogues of the drug
To date, the range of antifungal drugs is quite wide, but there are no structural analogues of Nystatin among such a variety. Therefore, when considering the substitutes for this medicine, we will focus on medicines that are similar in pharmacological action, and not in composition. The list of such tools is quite large, we will consider the most popular of them.
Means "Fluconazole"
This analogue of Nystatin in tablets is used to treat ailments caused by fungi. This tool, having a highly specific effect, inhibits the activity of enzymes of pathogenic microorganisms. The active substance of the drug prevents the conversion of lanosterol to elgosterol in fungal cells, as a result of which membrane permeability increases and pathogenic microorganisms die.
The medicine is available in three main forms: tablets, solution for infusion, capsules. In what form to use the drug, the doctor decides, depending on the location of the disease.
Reviews about the drug "Fluconazole"
Most patients who were able to defeat the disease with the help of this medicine respond positively about it. However, those who experienced side effects during therapy are not very happy with the medicine. Indeed, like the Nystatin drug, analogues, including the Fluconazole drug, can cause a number of negative, very serious reactions of the body. So, the use of this medication can cause flatulence, nausea, abdominal pain, dyspepsia, impaired liver function and many other ailments.
Means "Diflucan"
This antifungal agent is used both for mycosis of the skin and mucous membranes, and candidiasis of internal organs. Fluconazole is used as the main active ingredient in it. The drug is available today in capsules, in the form of a powder for self-preparation of a suspension and in the form of a solution for injection. This allows you to choose the most suitable way to use the medicine to achieve the best therapeutic effect, depending on the nature and complexity of the disease.
The advantage of the tool is that its use has no age restrictions and can be assigned even to crumbs from birth. It has a drug and an impressive list of adverse reactions, so patients' reviews about it are not always positive. But in most cases, people are satisfied with the results of treatment.
The medicine "Lamisil"
In case of ailments caused by fungi, not only Nystatin is prescribed. Analogs, such as Lamisil, can also be recommended for patients. This medication is available both in tablet form and in the form of a spray, ointment, gel, which allows you to use it both internally and externally. As the main substance that has an effect directly on the causative agents of the disease, pharmacists used terbinafine.
Patients who used the medication respond positively about it, exceptions are those isolated cases in which side effects were manifested.
Means "Candide"
Candide medication is intended for external use only and is available in the form of a solution, gel, suppositories and vaginal tablets. The substance Clotrimazole, which disrupts the process of ergosterol synthesis of fungal cells, is used at the heart of this medication, which leads to their destruction. An effective medicine for various types of candidiasis of the epidermis and mucous membranes, mycosis of the nail plates, fungal diaper dermatitis and other ailments caused by yeast and mold fungi.
As for contraindications to the use of the drug, there are practically none. Exceptions are the first trimester of pregnancy and increased sensitivity of the patient to the components of the drug.
The drug "Flucostat"
This medication is available in the form of capsules, injection and suspension. Its active ingredient is fluconazole, which successfully fights against cryptococcal and candidal infections by acting directly on the cell membrane of pathogens. It is prescribed to patients from 3 years, but the dosage and duration of treatment are determined by the doctor individually. The specialist is guided not only by the individual characteristics of the patient, but also by the degree of complexity of the disease. Self-medication with this medication can lead to many negative consequences, including arrhythmias, impaired renal function, etc.
Conclusion
So, we examined the drug "Nystatin." Instructions for use, analogues, reviews are now known to you. We hope you find this information useful.