High blood pressure is one of the reasons for the development of severe cardiovascular diseases. Drugs are prescribed to patients only by doctors, since their effects are strictly specialized. One such antihypertensive agent is Lozap. Instructions for use with the specified drug should be attached to each package from the manufacturer. The medicine is a small white pill, prescription in cardboard packages of 3 blisters in each. The blister contains 10 tablets.
The drug "Lozap" - what is it?
One tablet of the drug contains two main components: hydrochlorothiazide and the substance losartan. Pharmacists call the drug complex, since its purpose is most often practiced as part of combination therapy. The principle of action of the drug is to reduce the OPSS, as well as reducing the concentration of substances such as adrenaline, aldesterone. Due to the fact that the drug "Lozap" is an antagonist of angiotensin II receptors, it lowers blood pressure, has a diuric effect, lowers pressure in the pulmonary circulation. In addition, the drug enhances physical ability in patients with heart failure and prevents myocardial hypertrophy.
Indications for use
Doctors often prescribe Lozap to patients with hypertension. Instructions for use, however, contain a number of indications for taking this medication. It is used in combination therapy for heart failure, renal failure, as well as for preventive purposes, if it is possible to develop cardiovascular diseases.
Contraindications
The medicine "Lozap" has its contraindications. It is not recommended for patients who have:
- arterial hypotension;
- anuria
- childhood;
- adolescence;
- impaired kidney, liver;
- pregnancy, lactation;
- hypovolemia.
In addition, patients with hypersensitivity to its components, as well as patients taking ACE inhibitors should not use the medicine .
"Lozap": instructions for use, dosage
Taking the medicine is carried out in accordance with the diagnosis and the recommendations of the doctor. For the treatment of hypertension, a course of three to six weeks is prescribed, one tablet per day. Under certain conditions, the doctor may increase the dose to two tablets per day. Given that one tablet contains 50 mg of the active substance, then 100 mg will be the maximum daily dose.
Side effects
The medicine "Lozap" was tested in clinical conditions, as a result of which a number of possible side effects were determined:
- anaphylactic reactions;
- angioedema edema;
- arterial hypotension ;
- dizziness;
- dermatitis, itching, urticaria;
- hepatitis;
- migraine;
- liver failure ;
- respiratory type reactions.
Thus, doctors with extreme caution prescribe "Lozap". Instructions for use with the drug should be followed by patients without fail in order to avoid negative consequences.
Overdose
An overdose of the drug is manifested by tachycardia, hypotension, bradycardia. If an overdose is detected, symptomatic treatment is carried out , with stimulation of vomiting reflexes and mandatory gastric lavage.
Storage and dispensing conditions
The manufacturer prescribes to store "Lozap" in its original packaging at a temperature not exceeding 30 degrees. Tablets should be protected from moisture, stored in a dark place, inaccessible to animals and children. The release of the drug without a prescription is prohibited, due to the high risk of side effects with uncontrolled administration.