Each of us has had a sore throat at least once in a lifetime. Sometimes it went by itself, sometimes rinsing was required. But sometimes the pain was so severe and was accompanied by fever, chills, that the patient immediately ran to the pharmacy to buy antibiotics, the most common of which was Ampicillin. But is it always advisable to take such drugs with a disease such as angina? In this article we will try to answer all the questions that you might have about the use of the Ampicillin antibiotic.
What is he like?
Ampicillin is a broad-spectrum antibacterial drug that belongs to the group of semi-synthetic penicillins. It is effective against both gram-positive and gram-negative bacteria.
Antibiotic Ampicillin is used for diseases such as:
- respiratory tract infections (sinusitis, tonsillitis, pharyngitis, bronchitis, pneumonia);
- urinary tract infections (pyelonephritis, cystitis, acute glomerulonephritis, urethritis);
- infections of the biliary system (cholangitis, cholecystitis);
- infections of the gastrointestinal tract (dysentery, typhoid fever, paratyphoid);
- chlamydial infections in pregnant women.
Thus, it can be noted that the range of application of Ampicillin is very wide.
Is Ampicillin necessary for angina?
As can be seen from the list above, tonsillitis, that is, inflammation of the tonsils, is one of the indications for the use of an antibiotic. And tonsillitis is the same as tonsillitis.
However, not all so simple. The need to use any antibacterial agent for angina directly depends on its pathogen. Many have the opinion that angina is a typical bacterial disease, but this is absolutely not true. The causative agent of angina can be not only bacteria, but also viruses, fungi and protozoa.
Therefore, in order to understand whether an antibiotic will be effective for angina, it is necessary to find out its nature.
Signs of bacterial sore throat
The most effective method for identifying the pathogen is to sow on a nutrient-friendly environment for bacteria. However, this method is quite lengthy and can take more than one day. And with the appointment of antibiotics, it is better not to delay. Therefore, it is worth knowing several signs that will help suspect a bacterial tonsillitis:
- severe general condition of the patient with chills, sweating, drowsiness;
- fever, prone to increase;
- purulent plaque on tonsils with a possible spread beyond;
- bacterial blood picture on a general analysis: an increased number of neutrophils due to young forms (shift of the leukocyte formula to the left, neutrophilia), a high number of leukocytes (leukocytosis).
It is with such a clinic and general blood test data that the appointment of Ampicillin for purulent tonsillitis is indicated.
Operating principle
Like other penicillins, Ampicillin moves to the site of infection, that is, to the place in the body where bacteria actively multiply. There, it blocks the synthesis of proteins of their cell wall, thereby stopping their reproduction. As a result, the bacterial infection first attenuates, since new forms of bacteria do not appear, and then disappears, since already formed bacteria die.
Benefits
Below are the main advantages of using Ampicillin for angina:
- a convenient form of administration, the presence of both tablet and injection forms;
- a wide spectrum of action, that is, it is effective against many types of bacteria;
- minimal toxicity;
- low likelihood of antibiotic resistance, that is, the resistance of microorganisms to antibacterial drugs;
- high efficiency.
Ampicillin tablets: use
"Ampicillin" in tablets is available in plates of 10 pieces, 250 mg of the active substance in one tablet.
Instructions for use "Ampicillin" in tablets for adults:
- Tablets in a standard dosage of 250 mg 4 times a day by mouth 1 hour before a meal. It is necessary to drink a tablet with plenty of water. It is possible to increase the dose three times with an extremely severe course of the disease.
Basically, the course of Ampicillin therapy for angina lasts 1 week, in rare cases, in severe cases, prolongation of treatment is possible up to 2 weeks.
As a rule, relief comes after two days of taking the antibiotic, but this does not mean that you need to stop treatment. Interruption of the course of Ampicillin tablets with angina earlier than the term prescribed by the doctor can lead to a complication of the course of the disease, as well as to the development of the phenomenon of antibiotic resistance, which leads to a violation of the sensitivity of bacteria to this antibiotic. And this, in turn, requires a change in the antibiotic to a stronger, and therefore more toxic.
"Ampicillin" in injections: application
In addition to tablet forms, Ampicillin is also available in injection bottles of 0.5 and 1 gram volumes, 10 pieces in one package. Both intravenous and intramuscular administration of the drug are possible.
Instructions for use "Ampicillin" in injections:
- the recommended dose for adults is 250-500 mg 4 times a day; in severe cases of the disease, a dose increase of up to 10 grams per day is possible;
- dosage for children depends on age and body weight: for newborns, the recommended daily dose is 20-40 mg / kg body weight, and for older children - 50-100 mg / kg, this dose must be divided into 4-6 doses with an interval of approximately 6 o'clock.
Ampicillin for children
"Ampicillin" with angina in children is no less effective than in adults. For the convenience of its use, there is a special form of release - suspension.
The following are the dosages of the antibiotic for the treatment of angina in children:
- children under 1 year of age are given a drug in the calculation of 100 mg per 1 kilogram of body weight per day;
- for children over 1 year of age, the recommended dose is 100-150 mg / kg per day.
The dose also needs to be divided into several doses and take the drug before meals. Sometimes in the treatment of childhood sore throat in severe cases, it is necessary to refer to the instructions for the use of "Ampicillin" in injections, presented above. Moreover, for children, intravenous administration of the drug is recommended.
Application features
To achieve the best result in the treatment of tonsillitis "Ampicillin" and to avoid unwanted side reactions, you should adhere to the following guidelines and rules:
- the use of "Ampicillin" after a meal worsens its absorption, which leads to a decrease in efficiency;
- it is forbidden to rinse your mouth with a suspension of the drug, so this can lead to damage to the mucous membrane and worsen the course of the disease;
- taking an antibiotic should be combined with rinsing the throat with warm solutions of antiseptics, as this reduces inflammation in the throat, reduces pain and helps to recover more quickly;
- when using Ampicillin during pregnancy, strict monitoring by the attending physician is necessary, especially in the first trimester;
- breastfeeding is one of the contraindications to taking Ampicillin, however, if such a need arose, it should be taken strictly under the supervision of a physician, while breastfeeding should be stopped during therapy, and lactation can be resumed only 5 days after the end of antibiotic therapy .
Contraindications
As with any other medication, there are a number of contraindications for taking Ampicillin:
- a history of allergic reactions to beta-lactam antibiotics;
- malignant blood formation - lymphocytic leukemia;
- infectious viral disease that affects lymphocytes - infectious mononucleosis;
- severe liver diseases that led to the development of liver failure (hepatitis, cirrhosis);
- lactation period;
- the age of the child is up to one month.
With caution and under the strict supervision of the attending physician, you need to take "Ampicillin" in the following diseases and conditions:
- pregnancy;
- severe renal failure, which leads to difficulty in removing the drug from the body;
- bronchial asthma;
- history of bleeding.
Side effects
When taking Ampicillin, the following undesirable side reactions may occur:
- headache;
- nausea and vomiting;
- allergic reactions: skin rashes, itching, allergic rhinitis;
- abdominal pain.
If you notice any of these symptoms when taking an antibiotic, consult your doctor immediately so that he replaces it with another drug. No need to indulge in changing the antibiotic on your own, as this is also one of the factors in the development of bacterial resistance.
Reviews
There are many reviews and opinions on the Internet regarding the use of Ampicillin for angina. Mostly all these reviews are positive, Ampicillin has proven itself as an effective tool in the fight against purulent tonsillitis. Many people notice improvement on the second day of treatment, and full recovery comes after a week of therapy according to the instructions for use of "Ampicillin" in tablets for adults.
Doctors note that in order to achieve the most effective treatment, it is necessary to start it as soon as possible after the diagnosis of bacterial tonsillitis, it should be continuous and last exactly as long as the attending physician prescribed.
We hope that in this article you received an answer to the question of how to take Ampicillin for angina. But it is worth noting that all the tips in the article are purely recommendatory in nature, and antibiotic therapy is possible only with the appointment of a doctor!