The drug "Nimesulide" ("Nise") belongs to the group of NSAIDs (anti-inflammatory non-steroidal drugs). The medicine is made in the form of conventional tablets, dispersible (fast-acting) tablets and for resorption, granules for the preparation of syrup and solution, suspension. The active ingredient is nimesulide.
The medication has anti-inflammatory, analgesic, antiplatelet and antipyretic activity. The tool reduces pain and inflammation. The drug does not affect the progression of the pathology.
The drug "Nimesulide" instruction recommends for arthritis of a different nature, osteoarthritis, rheumatoid arthritis, bursitis, tendonitis. The drug is prescribed for acute pain, to eliminate post-traumatic and postoperative pain, with algodismenorrhea, headache and toothache, myalgia, arthralgia. The tool "Nimesulide" instruction recommends use for symptomatic treatment.
The medication is not prescribed for bronchial asthma, recurrent polyposis in the paranasal sinuses or nose, hypersensitivity, individual intolerance to acetylsalicylic acid and other NSAIDs (including in the history of the disease). The drug "Nimesulide" instruction does not allow for use with erosive and ulcerative lesions in the digestive system, active gastrointestinal, cerebrovascular and other bleeding. Contraindications include inflammation in the intestines, hemophilia and other disorders of the blood coagulation function. The drug is not prescribed for decompensated heart failure, liver failure, or any pronounced liver pathology. The medicine "Nimesulide" the instruction does not allow for use in progressive renal diseases, if there is a history of hepatotoxic reactions when using a medication confirmed by hyperkalemia. Not recommended after coronary artery bypass grafting, with the simultaneous use of hepatotoxic drugs. Contraindications include pregnancy, lactation. The drug "Nimesulide" is not prescribed for children under twelve years of age.
The medication is taken after a meal. The recommended dose is fifty or one hundred milligrams twice a day.
When using the drug, various side effects can be noted. The medicine can cause allergies, anaphylactic reactions, dizziness, Reye's syndrome, drowsiness, headache, nervousness, fear, nightmares. When taking the drug, sweating, angioedema, dermatitis, urticaria, erythema, and swelling of the face can be noted. Side effects include epidermal necrolysis (toxic), Stevens-Johnson syndrome, itching and a rash on the skin. Among the undesirable consequences, urinary retention, dysuria, kidney failure, hematuria, interstitial nephritis, oliguria are noted. Often when taking the medication, nausea, diarrhea, vomiting occurs. The drug can provoke constipation, gastritis, flatulence, tarry stools, stomatitis, epigastric pain. Bleeding in the digestive tract, an ulcer in the stomach or duodenum, cholestasis, jaundice, hepatitis (fulminant including) can also develop. The medicine "Nimesulide" in some cases causes hemorrhage, purpura, thrombocytopenia, eosinophilia, shortness of breath, anemia, exacerbation of asthma, bronchospasm. In rare cases, there may be a violation of the clarity of vision, tachycardia, lowering blood pressure, flushing of the face and upper body, hypothermia, general weakness.
Experts do not recommend the use of the drug "Nimesulide" for patients planning a pregnancy, due to the ability of the drug to negatively affect fertility.
Medication can reduce the speed of psychomotor reactions. Therefore, caution must be exercised in carrying out potentially hazardous activities.
Before taking the medicine "Nimesulide", you should carefully study the instructions.