In the article, we will review reviews about the treatment of HPV with Isoprinosine.
A large number of strains of the human papillomavirus becomes the cause of various neoplasms of the larynx, skin, genitals and other parts of the body. This virus is included in the cells, causing their active division, which, in turn, helps to accelerate the appearance of new virus particles, and some types of HPV can also cause malignant cell growth. There are several drugs, one of which is the Isoprinosine drug from HPV, whose distinctive advantage is the possibility of using not only adults, but also children.
The composition of the drug
The medication is available in the form of biconvex oblong tablets of almost white or completely white color with a slight amine odor.
The active substance of the drug is inosine pranobex. This compound is similar in structure to the "bricks" of DNA that exist in all living things on the planet, including humans. This is an analogue of special nitrogenous purine bases, due to which the production of new RNA and DNA molecules in human cells is stimulated. This is especially important for cells of the immune system, since they divide most actively, consuming a lot of nucleic acids (RNA and DNA are just their varieties). Each tablet contains five hundred milligrams of the active ingredient.
The properties
What effects does activation of nucleic acid production allow a person to get? How does this help in the fight against HPV? "Isoprinosine" contributes to such changes:
- The activity of lymphocytes, that is, the central cells of the human immune system, is restored. It is because of their “inaction” that HPV can be infected with the further appearance of neoplasms. According to medical statistics, more than half of the people on the globe are carriers of this virus, however, it manifests itself much less often due to the low activity of lymphocytes.
- Increases the activity of T-helpers and natural killers - highly specialized immune cells that are responsible for the destruction of cells already infected with the virus.
- It stimulates the release of interferon, that is, a biologically active component that detects infected cells, inhibits the development of the virus in them and attracts natural killers to it.
- In addition to interferon, the production of other active compounds of the immune system - immunoglobulins, interleukins, and so on, is also increasing.
- Activation of other immune cells - macrophages, neutrophils.
Mechanism of action
All of these effects significantly increase the body's resistance to various infections, especially of viral origin. In addition, the drug Isoprinosine with HPV can also affect viruses directly - like interferon, it slows down virus reproduction (blocks RNA synthesis) inside the cell. Due to this, the spread rate of infection throughout the body decreases, the immune system receives the necessary time (it is stimulated by the medicine) in order to collect and fight the virus.
But all the described effects are nonspecific, which means that they act when a person is infected with both HPV and many other viruses that cause influenza, measles, mononucleosis, herpes zoster, chickenpox and herpes. Therefore, experts advise drinking Isoprinosine for HPV, as well as for other infections. This drug is not prescribed for preventive purposes - clinical studies have shown that all the effects of the drug are less pronounced in the absence of infection, which means that there is no point in taking it.
Indications
The drug is used to restore and treat immunity in the following pathologies: herpes, SARS, human papillomavirus infection and others.
Treatment of HPV in women with Isoprinosine is highly effective. Papillomavirus can be very dangerous, it is expressed in the form of the appearance of harmless and simple warts or in oncological form. It is impossible to get rid of the virus to the end, but symptoms can be alleviated. Also, the risks of overgrowing papilloma into an oncological tumor are also reduced.
"Isoprinosine" with HPV type 16 will be effective if used along with other means. The medication is also prescribed when determining genital warts, genital warts, since they arise due to infection of the body with medium-oncogenic and low-oncogenic types of papillomavirus.
How to take "Isoprinosine" with HPV?
Dosage and administration features
If there are papillomas and other signs of HPV infection, the drug Isoprinosine is allowed to take from the age of three. However, it is very important to observe the correct dosage of the drug, since with the increase in the number, numerous side symptoms and complications can develop. On drugstore shelves you can find this drug in the form of tablets, each of which contains 500 milligrams of the active substance.
The therapeutic regimen for the treatment of HPV “Isoprinosine” does not depend on a specific form of pathology. It can be used with equal effectiveness with ordinary warts on the body and hands, and with genital warts, laryngeal papillomas, multiple papillomas and other forms. A number of experts advise drinking Isoprinosine and at the same time resorting to other methods of treatment - external cauterizing and antiviral agents, removal of neoplasms, etc. This increases the effectiveness of therapy many times and almost eliminates possible future relapses.
In the treatment of diseases provoked by HPV in adult patients, the following scheme is prescribed: 3-4 tablets a day, two tablets, that is, from six to eight tablets should be taken per day. The duration of admission should be at least two weeks, the course usually lasts from two to four weeks, after which you must definitely take a break for at least a month. If necessary, and under medical supervision, you can repeat the course.
In children
The use of Isoprinosine in children is possible from the age of three and with a body weight of at least 15 kilograms. The amount is calculated on the basis that five kilograms of the baby’s weight should be half a tablet per day. With a child weighing 15 kilograms, thus, half a tablet is drunk three times a day, 20 kilograms - four times a day in the same dosage, etc. The rest of the course does not differ from the treatment of adult patients with diseases due to HPV - the same duration of admission and a break for a month.
With other viral pathologies, there may be changes in the regimen, therefore, when buying a medicine, you should carefully read the instructions in which recommendations are given regarding the treatment of all diseases. It is important not to confuse the description of HPV treatment with the treatment of another disease.
Contraindications
Isoprinosine tablets with HPV are very well tolerated by most people, but a number of contraindications to use do exist. They are mainly caused by the metabolism of inosine pranobex in the human body, which is processed in the kidneys and liver with the production of insoluble uric acid, and it, in turn, can cause problems during the use of the drug.
The main contraindications for Isoprinosine are as follows:
- Gout is a pathology in which uric acid deposits in the joints, kidneys and other tissues. Of course, its increased production as a result of the use of the drug, the course of this disease will not improve.
- Urolithiasis, that is, some of its forms, accompanied by the formation of urate stones (from salts of uric acid). Similar to the previous case, the production of an additional volume of uric acid can worsen the patient's condition.
- Chronic kidney failure - almost all uric acid produced during the metabolism of the drug’s substances is eliminated through the kidneys. If their work is difficult, then this substance accumulates in the body in the form of crystals and stones.
- Arrhythmias - it is determined that a medicine in some cases can disrupt the rhythm of heart contractions.
- Intolerance to the composition of the drug - the appearance of allergic reactions in the form of itching and a rash on the skin makes it cancel its use.
Side effects
Among the side effects, nausea (sometimes turning into vomiting) and dizziness are most often noted, weakness rarely occurs. The use during lactation or pregnancy by most specialists is not recommended - mainly due to the lack of research in this area. Therefore, there is no accurate information about the effect of Isoprinosine on the development of the baby or the pregnancy process. In addition, the drug is prohibited for patients under three years of age.
Alcohol intake
During treatment, it is not recommended to drink alcohol, since both ethyl alcohol and the drug are processed in the liver, and the products of such processing are excreted by the kidneys. That is why the load on these organs is greatly increased, severe intoxication may appear even with the use of a small amount of alcohol.
“Groprinosin” or “Isoprinosine” for HPV?
Isoprinosine is a rather expensive drug, and many patients wish to purchase a more affordable analogue. It should be noted that the full analog should have the same active substance as in the original medicine. Generic, unlike the brand, does not pass clinical trials. The absence of costs for them positively affects the cost. Therefore, generics are cheaper anyway. The Russian pharmaceutical market, unfortunately, is not able to offer many analogues with pranobex inosine. So, only one drug is registered - Groprinosin, produced in Hungary and Poland. Due to the presence of the letter s in the Latin name, the name is sometimes spelled "Groprinosin" when translated. Its cost is slightly lower compared to Isoprinosine, but the difference is not too great. For example, with the purchase of 20 tablets, the savings will be only from 50 to 70 rubles compared to the original product. I must say that the quality of "Groprinosin" and "Isoprinosin" is approximately at the same level. If you replace the original with an analog, you can be sure that both drugs are completely identical.
What other analogues of Isoprinosine for HPV can be used?
Other substitutes for this drug
There are drugs with antiviral activity that are used to prevent and treat infections. Zinerit, Amiksin, Panavir, 5 NOCs, Arbidol, Acyclovir received positive reviews from doctors and patients.
Drug analogs differ in immunostimulating and antiviral effects, but are often less effective in comparison with Isoprinosine. Specialists prescribe such drugs in tablets with a similar therapeutic effect in the treatment of chronic viral diseases, HPV: Kagocel, Alpizarin, Lavomax, Hyporamine, Amizol, Ergoferon, Allokin-Alpha, Tiloron "," Tilaxin. "
Reviews on "Isoprinosine" with HPV
Most doctors and patients report a noticeable antiviral effect of the drug. Experts quite unanimously respond about the drug: "Isoprinosine" works really, reducing the duration of the disease and mitigating the signs of infection. It must also be emphasized that the medication is a prescription. Only a competent specialist is able to correctly choose a treatment regimen that will organically combine the amount of drugs.
Reviews of Isoprinosine for HPV should be consulted in advance.