Many people are allergic to dust mites. The use of antihistamines gives only temporary relief, because these drugs do not affect the cause of the disease. Nowadays, the drug "Lys Dermatophagoides" has been created, which is used for desensitizing therapy. This method of treatment consists in the introduction of small doses of neutralized allergens.
Gradually, the body adapts to these substances. The sensitivity of the immune system to the waste products of dust mites is reduced. As a result, allergies do not occur. Consider this drug in more detail.
Composition and action
The composition of the drug “Lys Dermatophagoides” includes neutralized allergens of two types of dust mites (in equal proportions):
- Dermatophagoides pteronyssinus. This parasite lives in the dusty corners of a person’s home. The greatest accumulation of ticks is noted on upholstered furniture and in carpets.
- Dermatophagoides farinae. The habitat of the parasite is a bed and bedding.
During the production of the drug, natural tick-borne allergens undergo chemical modification. At the same time, their activity is significantly reduced, they lose the ability to interact with immune cells. Such treated allergens are not harmful to the body.
The drug is produced in the form of tablets for resorption under the tongue. Each of them contains a mixture of tick-borne allergens in a dosage of 300 or 1000 AE. The composition of the medicine also includes additional ingredients: cellulose, magnesium salt of stearic acid, lactose and silicon dioxide. One pack contains 30 tablets.
Indications
Hypersensitivity to dust mites waste products is the only indication for the use of the Lys Dermatophagoides drug. The instructions indicate that desensitizing therapy is possible only with confirmed by laboratory tests of hypersensitivity to microorganisms living in dust.
Before starting treatment, you need to accurately establish the type of allergen that provokes a negative reaction of the body. To do this, you must pass a prik-test (skin test). If the analysis shows the presence of allergies to dust mites, then this is an indication for desensitizing therapy.
The drug is also used in pediatric practice. It can be prescribed to children from the age of 5 years.
The treatment with the Lys Dermatophagoides drug is long and expensive. The purpose of this medication is necessary only with frequent and persistent allergic reactions. If the patient's pathology is occasionally manifested, then conducting desensitizing therapy is impractical. In this case, antihistamines should be used.
Contraindications
Not all allergy sufferers can be prescribed desensitizing therapy with Lys Dermatophagoides. The instructions for use indicate the following contraindications to the use of this tool:
- The patient is under 5 years old.
- Allergy to the auxiliary ingredients of the tablets.
- Autoimmune pathologies.
- Malignant tumors.
- Immunodeficiency conditions.
- Severe heart and vascular disease.
- Pulmonary pathologies and bronchial asthma.
- Chronic diseases
- Contraindications to the introduction of adrenaline.
- Reception of beta-blockers.
During pregnancy, the drug is prescribed only in exceptional cases. The lactation period is not an absolute contraindication to the use of the drug, but therapy should be carried out under strict medical supervision.
Desensitizing treatment is not carried out during the acute period of infectious diseases. Therapy is delayed until the patient recovers.
Undesirable consequences
Lais Dermatophagoides tablets contain only modified and neutralized allergens. Therefore, side effects are very rare. This drug is quite safe.
However, in the first days of treatment, some patients may experience manifestations resembling a mild allergic reaction:
- Itching of the lips and mouth.
- Nausea.
- Swelling of the lips and tongue.
- Stomach ache.
The patient should always inform the doctor about such symptoms. In this case, the specialist will reduce the dosage of the drug. Most often, such phenomena pass on their own as the body adapts to the allergen.
Very rarely, against the background of treatment, pronounced signs of the disease are observed:
- Rashes by the type of urticaria.
- Quincke's edema.
- Severe runny nose.
- Bouts of asthma.
For all the time the drug was used, such severe reactions were observed in only a few patients. In such cases, therapy is immediately discontinued. Adrenaline and corticosteroids are used to stop side effects.
It is important to remember that this drug can be taken only on the recommendation of an allergist. During therapy, the patient should be under medical supervision.
Initial stage of therapy
The drug should be used only in the morning on an empty stomach. The tablet is placed under the tongue and held for about 2 minutes. Then it can be swallowed.
Desensitizing therapy is started with small doses of the Lys Dermatophagoides drug. The initial course of treatment is carried out in tablets with a dosage of 300 AE. In the first 4 days, the following medication regimen is used:
- First day: 1 tablet.
- Second day: 2 tablets.
- The third day. 3 tablets.
- Fourth day: 4 tablets.
This amount of the drug is consumed in one go.
From the fifth day of therapy, tablets with a dosage of 1000 AE are used. They are consumed 1 piece once a day. The medicine is taken for 5 days, followed by a two-day break, after which the therapy is resumed according to the same scheme. The duration of the initial course is determined by the doctor. If the patient experiences undesirable effects, the dosage is reduced.
Supportive treatment
After the patient has improved, maintenance therapy is used. The drug is taken in a dosage of 1000 AE two or three times a week. Such treatment takes from 3 to 5 years. After the end of therapy, the effect lasts about 7 years. Then, the course of taking the drug is repeated if necessary.
Application features
During desensitizing therapy with Lys Dermatophagoides, the following rules must be observed:
- Completely eliminate the use of alcohol.
- Within 2 hours after taking the tablets, avoid physical stress.
- Tell your doctor about all medications you take.
During therapy, patients are not forbidden to drive a car. However, in some people, treatment may decrease concentration. In such cases, it is better to give up driving.
Infectious Disease and Vaccination Treatment
If the patient is sick with SARS, the flu or other acute infectious pathology accompanied by fever, then the pill is interrupted. You can resume allergy treatment only after complete recovery.
There are times when the patient needs to be vaccinated during desensitizing therapy. Taking tablets should be stopped 1 week before vaccination. 14 days after the administration of the vaccine, treatment is resumed.
If the break in taking the medicine is less than 2 weeks, then the drug continues to be taken at the same dosage. If the course of treatment was interrupted for a longer period, then the doctor selects the required dose of tablets.
Storage, price, analogues
The packaging with tablets may be stored at a temperature not exceeding +25 degrees. The medicine remains valid for 3 years.
The price of the drug is from 9,000 to 10,500 rubles. On sale you can find sets of tablets for the initial course of therapy (300 AE + 1000 AE) and for maintenance treatment (1000 AE). The manufacturer of the medicine is the pharmaceutical company Lofarma (Italy).
Prescription pills are available. This medicine is not intended for self-administration.
Are there any cheaper sensitizing agents than Lys Dermatophagoides? The analogues of the drug include:
- "Alustal Allergen ticks" (JSC "Stallergen").
- "Tick Allergen" (OJSC "Biomed").
These medicines cost from 3,000 to 5,000 rubles. However, they are less convenient to use, since they are produced only in injectable form.
There are other analogues of the drug intended for sublingual and oral administration:
- "A mixture of ticks" ("Sevafarma").
- "Staloral Allergen ticks" (JSC "Stallergen").
- "Antipollin."
Of the above analogues, the most economical option is the Staloral Allergen Mite Drops and Antipollin tablets. Their price is from 4000 to 5500 rubles. The drug "A mixture of ticks" of the Czech company "Sevafarma" costs about 10,000 rubles.
Patient opinion
Most patients have a positive opinion about the drug "Lys Dermatophagoides." The reviews reported the complete disappearance of allergic reactions after desensitizing therapy. However, it is very important to complete the course of treatment. If you stop taking the pills earlier, then a relapse may occur.
This drug has been used in Russia relatively recently. Therefore, it is still difficult to assess the duration of the therapeutic effect. However, many patients report that after the course of treatment they did not have allergic reactions for 4 years or more. The duration of action of the drug on the body is individual and may vary in different people.
Some patients report that in the first week of treatment they were bothered by a slight itching and runny nose. However, as the body gets used to the allergen, these manifestations disappeared on their own.
There are practically no reports of severe side effects of the drug. However, some patients write that desensitizing therapy did not help them. Against the background of treatment, patients still had undesirable reactions.
It is important to remember that patients often have a polyvalent allergy when a person has an increased sensitivity to several types of irritating substances. A negative reaction during therapy could be caused not by dust mites, but by other irritants. Therefore, before starting treatment, it is recommended to do a comprehensive analysis. He will show all types of allergens to which the patient's body is sensitive. Such patients are shown combination desensitizing therapy with several types of drugs.