The drug "Cetirizine Hexal" is a third generation antihistamine. This selective H1 receptor blocker actively binds to plasma proteins. The drug penetrates poorly through the BBB, practically does not inhibit the central nervous system.
The medicine "Cetirizine Hexal" (the instruction contains such information) reduces the effect of mediators of an allergic reaction. The drug has an overwhelming effect on the migration of eosinophils during atopic reactions.
The drug "Cetirizine Hexal" is rapidly absorbed. The maximum concentration of the drug in the blood is noted forty-sixty minutes after administration. Pronounced therapeutic efficacy is observed after four to eight hours and lasts for a day.
Tablets "Cetirizine" is prescribed as a symptomatic treatment of allergic rhinitis (chronic year-round and seasonal), allergic conjunctivitis, atopic dermatitis, chronic urticaria (idiopathic).
The medicine is prescribed to patients from the age of twelve at ten milligrams per day. It is recommended to take the drug in the evening. Dosage for children from six to twelve years is established based on body weight. With a weight of less than thirty kilograms, five milligrams per day is prescribed. Each tablet has a notch with which you can divide the medicine in half. Children weighing more than thirty kilograms are prescribed a tablet divided into two doses per day (five milligrams in the evening and in the morning).
The drug is swallowed whole, the medicine should not be chewed. Instructions for use allow you to take the drug "Cetirizine" regardless of food intake.
The drug is available in the form of a suspension. A measured spoon, corresponding to five milligrams of the drug, is attached to the medicine. The dosage regimen set for the solution is the same as for tablets.
The duration of treatment for each patient is individual. On average, the duration of use of Cetirizine (instructions for use indicates this) is from two to four weeks. With chronic urticaria and chronic rhinitis (allergic), the duration of the course can be up to a year. With seasonal rhinitis, the duration of treatment is from three to six months.
For patients with renal failure, the dosage should be halved.
For patients with liver failure, the dose of the drug โCetirizineโ is recommended for use individually, especially in the presence of concomitant renal failure.
For elderly patients, dosage adjustment may be required.
The medicine "Cetirizine" instruction for use does not allow for appointment with severe nephropathy, hypersensitivity, during pregnancy and lactation. Medication is contraindicated for children under two years of age (in the form of a solution). Tablets are not prescribed for children under six years of age.
When using the drug, adverse reactions are extremely rare. The drug can cause headaches, agitation, skin rashes, and weakness. In some cases, increased fatigue, xerostomia (dry mouth), abdominal pain, laryngitis are noted. The medicine "Cetirizine" can provoke angioedema, bronchospasm, nosebleeds, nausea, diarrhea, cough. In some patients, hypersensitivity reactions were recorded, as well as the hepatoxic effect of the drug (increased transaminase activity, hepatitis).
With an overdose, drowsiness is noted, the severity of side effects increases. To alleviate the condition, standard detoxification measures are taken: gastric lavage, and enterosorbents are also prescribed. Subsequently, if necessary, carry out symptomatic treatment.
About the drug "Cetirizine" reviews are generally positive. As many patients testify, the remedy quite effectively eliminates the symptoms of allergies.
Before using the medicine, consult your doctor.