Xymelin with menthol is available as a clear, colorless liquid. This is a locally acting vasoconstrictor drug used to treat a runny nose and various otolaryngological diseases. In the process of contact with the nasal mucosa, this tool helps to narrow the vessels dilated due to the common cold, as a result, swelling decreases, and at the same time, irritation of the mucosa is minimized. Against the background of the use of the drug in question, patients breathing through the nose normalize, and the volume of mucous secretions decreases. The patient sneezes much less often. "Xymelin" with menthol due to the presence of this component in the composition enhances the therapeutic effect produced by the drug.
Structure
The main components in this tool are xylometazoline hydrochloride and levomenthol. The excipient is sorbitol, along with hydrogenated castor oil, eucalyptol, sodium chloride, disodium edetate and purified water.
Release Forms
"Xymelin" with menthol is available in the form of a nasal spray for children in dark glass bottles of 10 milliliters with a tip, a dispenser and a protective cap. In the pharmaceutical market there is also a spray for adults - 10 and 15 milliliters each.
Also on sale is another type of this medicine in the form of drops. It is available in dark 10 ml dropper bottles. This drug, intended for local use, in otolaryngological practice belongs to the vasoconstrictor clinical and pharmacological group.
Pharmacological effects
So, the tool in question today is widely applicable in otolaryngological practice. Xymelin with menthol acts as an alpha-adrenergic agonist, causing a narrowing of the blood vessels of the nose. Thanks to this, edema and hyperemia of the mucous membrane of the nasopharynx are eliminated. In parallel, nasal breathing during rhinitis is facilitated in patients. It is worth noting that in therapeutic doses, this drug does not irritate the mucosa and does not provoke hyperemia. The action occurs, as a rule, after a few minutes and lasts for ten to twelve hours.
Pharmacokinetics
According to the instructions, "Xymelin" with menthol in the process of local application is practically not absorbed. It is worth saying that its plasma concentrations are very small, and so much so that they cannot be determined using modern analytical methods.
Indications
According to the instructions for use, Xymelin with menthol is suitable for patients with the following diseases:
- The appearance of acute respiratory diseases with manifestations of rhinitis (i.e., a runny nose).
- Against the background of hay fever, sinusitis, eustachitis and otitis media (to combat swelling of the nasopharyngeal mucosa).
- In case of acute allergic rhinitis.
- As part of the preparation of the patient for diagnostic manipulation in the nasal passages.
Instructions for use
Ximelin spray with menthol and drops are administered intranasally (that is, in the nose). Before this procedure, it is necessary to clear the passages of any mucous secretions. Drops are instilled in a standard manner. As part of the use of the spray, the protective cap must be removed from the bottle, after which, carefully insert the tip with the spray into the nasal passage and press the nozzle while inhaling. The medicine should irrigate the entire mucous membrane of the inflamed nasal cavity. The same manipulation is repeated in the second nostril.
The instructions indicate that the drug "Xymelin" is not recommended for use more than three times a day and longer than one week. Adults need to use a spray or nasal drops of 0.1% (three drops in each nostril) no more than three times a day. Quite often, “Xymelin” with menthol is prescribed to adults in a single dose twice a day. The treatment course is ten days.
Xymelin for children
It is worth emphasizing that, according to the instructions, this pharmaceutical preparation is not prescribed for babies up to two years old. Indications for use of the medication in children are the same as in adults. Pediatricians usually prescribe nasal drops or 0.05% spray to small patients from two to six years of age: one injection into each nostril no more than two times daily. Children over six years old need to use nasal 0.1% drops: 2-3 drops in each nostril no more than three times a day. The instructions also indicate that "Xymelin" with menthol is preferable to use for children from the age of ten.
Side effect
As follows from the instructions, with prolonged or too frequent use, patients often experience irritation in combination with dry nasopharyngeal mucosa, burning, paresthesia, sneezing and hypersecretion.
Very rarely, swelling of the nasal mucosa can be recorded along with palpitations, tachycardia, arrhythmias, increased pressure, headache, vomiting, insomnia and impaired vision. Additionally, it is reported that patients experience depression in the case of prolonged use of Xymelin with high doses of menthol.
Contraindications
The described nasal drops, as well as the spray, may not be suitable for every patient, and therefore it is necessary to be careful. For example, this vasoconstrictor drug should not be used for treatment in a number of the following cases:
- Against the background of arterial hypertension and tachycardia.
- In the case of severe atherosclerosis, glaucoma and atrophic rhinitis.
- With thyrotoxicosis and surgical interventions on the meninges (in history).
- During pregnancy or childhood up to ten years.
- In the presence of excessive sensitivity to menthol.
With caution, it is necessary to use this drug for diabetes, angina pectoris, related to the third or fourth functional class, and in addition, men with prostatic hyperplasia.
During pregnancy
"Xymelin" with menthol is strictly contraindicated during pregnancy, therefore, during a cold, ladies in position should refuse to use it and choose an alternative means of combating the disease with the attending physician.
During breastfeeding, this medication should be used only after a thorough assessment of the expected benefits of the treatment for the mother and the possible risks for the small child. Exceeding the recommended dose should not be allowed.
special instructions
Patients are not recommended to use nasal drops or spray with Xymelin menthol for a long time, for example, with chronic rhinitis. In the event that the symptomatology of the disease worsens or the person’s condition does not normalize for at least three days of using this medication, it is necessary to consult a doctor. The drug does not affect the ability of people to drive a car or sophisticated equipment.
Alcohol compatibility
There is no information on the use of Xymelin during alcohol use. It is important to understand that alcoholic beverages adversely affect the immune system, which can slow down the healing process.
Interaction with other medicines
Under the ban, the combined use of "Xymelin" and tricyclic antidepressants. It is also impossible to combine the use of a spray with the intake of biologically active components that inhibit the enzyme monoamine oxidase.
Overdose with this medication
Symptoms of an overdose, as a rule, consist of increased side effects. Therapy in this case is reduced to discontinuation of the drug.
An overdose of the drug can lead to:
- dizziness, migraines;
- heart palpitations;
- feeling sick with vomiting;
- visual impairment;
- increase in pressure;
- allergic reactions.
To eliminate these symptoms, you must immediately consult a doctor and carry out maintenance treatment.
Reviews about the drug
Reviews about "Xymelin" with menthol are very contradictory. The advantages of the medicine, many consumers include the presence of a convenient dispenser, the rapid achievement of the effect and the duration of action. But, according to patients treated with this vasoconstrictor, there are also disadvantages. For example, dryness of the nasal mucosa after applying the spray has been reported.
Some patients emphasized that with frequent or prolonged treatment, they became addicted to Ximelin drops with menthol. True, according to doctors, those who strictly adhere to the dosage, adhering to all the recommendations of the doctor, and do not exceed the indicated duration of the course, have no risk of getting used to the drug. It is also noted that this medication perfectly normalizes breathing thanks to menthol.
Experts explain that the main task of this drug is to act on the maximum area of the mucosa. That is why its use allows you to quickly deal with rhinitis. The tool, falling into the nasal cavity on inspiration, penetrates inside, immediately starting to act on the mucous membrane, covering it completely in all directions.
Thus, based on the majority of reviews of doctors and patients, we can say that people are quite satisfied with the results of treating a cold with the help of this medicine, and also consider it effective and safe.