The medicine "Aminazin" has been used in medical practice as one of the main antipsychotics for a long time. The use of the drug in therapeutic dosages does not cause drowsiness. The active substance is chlorpromazine.
The drug "Aminazin" instructions for use refers to phenothiazine derivatives. The medicine has a sedative (sedative) and antipsychotic effect. The use of the drug allows you to completely reduce or eliminate hallucinations and delusions, reduce affective reactions, anxiety, anxiety, and motor activity (psychomotor agitation). Taking high doses of the drug "Aminazine" (overdose) can cause drowsiness, depression, extrapyramidal disorders. The drug is also able to increase the secretion (secretion) of prolactin.
Describing the drug "Aminazine", the instructions for use indicate its antihistamine, alpha-adrenergic blocking and weak m-anticholinergic activity. The drug is able to lower blood pressure.
The central mechanism of action of the drug is associated with blockade of dopamine receptors in various brain regions. The calming effect is probably based on a blockade in the central adrenergic receptors.
Once inside, the medicine is rapidly absorbed from the digestive system. Excretion is carried out mainly with feces and urine. The half-life is very long (from four weeks or more).
The medicine "Aminazine", the instructions for use recommends for conditions of hallucinatory-paranoid and paranoid chronic course, psychomotor agitation against schizophrenia (with catatonic, hebephrenic, hallucinatory-delusional syndrome).
The drug is indicated for alcoholic psychosis, neurotic pathologies, complicated by increased muscle tone, to relieve pain, including causalgia (burning pain) in combination with painkillers.
The medicine is prescribed for persistent sleep disturbances (in combination with tranquilizers and sleeping pills), mental disorders on the background of epilepsy, manic agitation and agitated depression in case of manic-depressive psychosis.
The drug "Aminazin" instructions for use allows for appointment with vomiting of pregnant women, Meniere's disease, itchy dermatoses. The drug is used in anesthesiology. In addition, the medication is indicated as a prophylaxis and treatment of vomiting during therapy with antitumor agents, with radiation therapy.
The dosage regimen is determined individually for each patient.
Typically, the daily dose of adults is not more than one and a half grams, once it is allowed to take no more than 300 mg. For children, the amount of the drug is prescribed at the rate of one milligram per kilogram of weight.
Taking medication can provoke a number of adverse reactions. The most likely negative effects are dyspeptic symptoms, tachycardia, hypotension, dry skin.
The drug "Aminazine" is contraindicated in brain injuries, in a coma, in the late phase of bronchiectasis, thromboembolism, decompensated heart defects. Do not prescribe a remedy for myxedema, progressive pathologies in the brain or spinal cord, impaired activity of the kidneys, liver, and hematopoietic organs.
special instructions
If the patient is prescribed to take the medicine “Aminazine” (in tablets or injections) at home, then after use it is recommended to be in a horizontal position for at least an hour and a half. Do not make sudden movements. This is due to the ability of the drug to lower blood pressure.
The medicine "Aminazin" is not intended for use by patients on their own.