Why can a drug “Vazoket” be prescribed by a doctor? Instructions for use and indications of this tool will be discussed in this article. From it you will learn about what analogues this medicine has, what is included in its composition (active and auxiliary substances), in what form it is released, what contraindications and side effects it has.
Composition, form and packaging of the medicinal product
This drug can only be purchased in the form of oblong tablets (600 mg). What does the “Vazoket” product contain? The composition of the medication is indicated in the instructions. She states that the main active ingredient of such tablets is diosmin. As for the auxiliary elements, they include povidone, magnesium stearate, corn starch and microcrystalline cellulose.
The drug "Vazoket" (tablets) goes on sale in blisters, which are placed in a cardboard box.
Pharmacological properties
What is the drug "vazoket"? Instructions for use states that its active ingredient is diosmin. As you know, this element has a good venotonic effect. It allows you to reduce the extensibility of veins, increase their tone (a dose-dependent effect occurs) and reduce venous congestion.
We can not say that the drug in question significantly improves lymphatic drainage. This happens due to an increase in the frequency of contraction of capillaries (lymphatic) and their tone, as well as an increase in their functional density and lowering of lymphatic pressure. In addition, such tablets are able to improve microcirculation, increasing the resistance of capillaries and lowering their permeability.
Specialists have proved that this drug improves perfusion in skin tissues, oxygen diffusion, and also reduces the adhesion of leukocytes to venous walls and their movement into paravenous tissues. It has an anti-inflammatory effect, enhances the vasoconstrictive effect of adrenaline, serotonin and norepinephrine, and also blocks the synthesis of thromboxane, prostaglandins and the production of free radicals.
Pharmacokinetics
Where is the absorption of the drug "Vazoket"? Instructions for use informs that after taking 1 tablet inside, the drug is absorbed quite quickly from the digestive tract. In the patient's blood plasma, the drug is determined after about two hours. Its highest concentration is reached after 5 hours after administration.
The agent under consideration, or rather its active component, is evenly distributed, and subsequently accumulates in almost all layers of the walls of the hollow and saphenous veins of the lower extremities. Small concentrations of the drug are found in the liver, pulmonary system, kidneys, as well as other internal organs.
The accumulation of diosmin (selective), as well as its metabolites in the veins and vessels, reaches its maximum after 9 hours after taking the tablets. This effect persists for 96 hours.
79% of the drug in question is excreted with urine, 11% with feces and 2.4% with bile.
Indications
Vazoket tablets, the instructions for use of which are presented in this article, are prescribed to patients according to the following indications:
- exacerbation of hemorrhoids;
- dilatation of the veins (varicose) of the lower extremities;
- microcirculatory disorders;
- chronic lymphatic venous insufficiency of the legs.
Contraindications
Are there any contraindications to the drug "Vazoket"? Instructions for use indicate that this medication has virtually no contraindications. However, experts argue that such a tool is highly not recommended for people under the age of 18. Also, this drug should not be prescribed to patients with hypersensitivity to certain substances of the drug.
Venotonic agent "Vazoket": instructions for use
We will provide patient reviews about this medicine at the very end of the article. As for this section, in it we will consider the dosage of a medical product and methods of its administration for various diseases.
Prescribe this drug should only a narrow specialist after examining the patient. With such a deviation as the expansion of the veins (varicose) of the lower extremities, as well as in the initial stage of chronic lymphatic insufficiency (that is, with heaviness in the legs), the considered drug is usually prescribed 1 tablet per day. The drug is taken early in the morning, before breakfast. The duration of such treatment is 2 months.
If the patient has severe forms of chronic lymphatic insufficiency (pain, swelling and cramps are observed), then the drug therapy is increased to 4 months. In the presence of trophic changes in the legs and the appearance of ulcers, the drug is taken for six months, and sometimes longer. This course is repeated every 3 months.
Does hemorrhoids medication "vasoket"? Reviews of patients say that with acute inflammation of hemorrhoidal nodes, such a tool helps very well. The main thing in this case is to strictly follow all the instructions of the instruction.
With exacerbation of hemorrhoids, this drug is prescribed in the amount of 2-3 tablets per day. It is recommended to take it with meals during the week. After seven days, medication can be continued. However, in this case, the dose should be reduced to 1 tablet per day for 1.5-2 months.
Is it possible to take the drug in question for women during gestation? With chronic lymphatic insufficiency in the 2nd and 3rd trimesters of pregnancy, the drug can be prescribed in the amount of 1 tablet per day. In this case, the medication is canceled 3 weeks before the expected onset of childbirth.
As for the lactation period, during the breastfeeding of the newborn, the drug should be discontinued. This is due to the fact that it passes into breast milk.
If the patient has missed one or more doses of the drug, then therapy should be continued as usual.
Overdose
Currently, cases of overdose by the considered agent have not been identified. Symptoms of this condition are not described in the instructions.
Interaction with other means
There is no clinically significant effect of this drug on other agents. Therefore, the medicine "Vazoket" is often prescribed in combination with other medicines.
Side effects
What undesirable consequences can the reception of the medicine “Vazoket” cause? Instructions, reviews about this tool inform that it has no side effects. However, in some cases, this drug can cause headaches, as well as cause dyspepsia. In this case, you must stop taking the medicine and consult a doctor. In turn, the doctor must prescribe another, safer drug.
Special instructions for the use of the drug
Before using this tool for the treatment of certain diseases, it is necessary to familiarize yourself with the instructions, as well as consult with an experienced doctor. Only in this case, therapy with this drug will be highly effective.
Treatment of inflamed hemorrhoidal nodes must be carried out only in combination with other agents (for example, together with rectal suppositories, ointments, etc.). In the event that a quick clinical effect has not yet occurred, then an additional medical examination is required, as well as adjusting the treatment. To do this, contact a proctologist.
Currently, there is evidence that this drug is highly effective in the treatment of placental insufficiency. It is also often prescribed for the prevention of bleeding that occurred after the use of intrauterine devices, as well as during phlebectomy.
Terms and conditions of storage of the drug
The medication in question must be stored in a darkened place inaccessible to children, at a temperature of no more than 30 ° C. The shelf life of this medicine is 3 years. After 36 months, the use of the medication is prohibited.
Cost and analogues of the drug
Like any venosonic drugs based on diosmin, the drug "Vazoket" is quite expensive. So, for 30 tablets you will have to give about 650-700 Russian rubles. In the treatment of acute hemorrhoids, approximately 90 tablets will be needed, which is noticeably affordable.
What can replace the drug "Vazoket"? Analogs of this medication also contain such an active substance as diosmin. Replace the drug in question with one of the following drugs: Venolek, Detralex, Diovenor 600, Diosmin, Phlebof 600, Phlebodia 600, Mediven.
The cost of these funds is similar to the price of the medicine “Vazoket”. However, there is another medicine that is much cheaper than the ones presented above. This is a Venus drug. Diosmin also acts as its active element. Although it should be noted that many patients talk about the poor effectiveness of this tool.
Patient reviews about the drug
What do patients say about a drug like Vazoket? We will review the reviews right now.
After treatment with this drug, many patients report lightness in the lower extremities. The medication is able to eliminate leg pain, cramps, congestion and swelling. He also quite quickly solves the problem associated with microcirculatory disorders.
As for acute hemorrhoids, on the second day of taking the dosage indicated in the instructions, patients observe a decrease in inflammation of the nodes. Although in most cases this happens only if the patient used the drug in combination with other drugs, including local ones (ointments, suppositories, etc.).