Means "Trilon B" (disodium salt of acid ethylenediaminetetraacetic acid) is a crystalline white powder. The drug is soluble in water, almost insoluble in ether and alcohol.
The drug "Trilon B" in medicine
The tool can form various complex compounds with a number of cations, including calcium ions. These properties allow the drug to be used in pathologies complicated by excessive accumulation of calcium salts in the body (including internal organs, muscles, venous walls), against the background of ossification of the skeleton, with arthritis, scleroderma. In some cases, the drug is prescribed to eliminate some types of ectopic arrhythmias, especially those caused by an overdose of cardiac glycosides. Due to the ability of the product to bind calcium ions, it is also used in blood preservation as an anticoagulant.
The drug "Trilon B". Application
The main indication for the appointment of a medication is pathology with manifestations of calcification. These include, in particular, scleroderma, dermatomyositis, ossifying myositis. The introduction of funds is carried out drip intravenously. Before infusion, the drug is diluted with sodium chloride (isotonic solution) or glucose solution (five percent). The introduction of the drug "Trilon B" is carried out at a speed of up to 12 drops / min. Patients from ten years old are recommended 10 milliliters of a five percent solution diluted with 200 ml of solvent. The medicine is administered in cycles. Patients under 10 years of age are prescribed 5 ml of the drug diluted in 100 ml of solvent. The course of therapy includes fifteen injections. The medication is administered once a day for five days with weekly breaks. Thus, the course includes three five-day cycles with seven-day intervals.
Contraindications and side effects
The drug "Trilon B" is not recommended for reduced blood coagulation, hemophilia, liver or kidney pathologies. Contraindications include hypocalcemia. During administration at high speed, tetany is likely to develop. In this case, stop the infusion. When injecting Trilon B into a vein, some patients experience a burning sensation that can spread throughout the body and persist for one or two hours after the injection.
special instructions
During therapy, it should be noted that the effectiveness of the drug without the manifestation of negative consequences is possible with a low rate of introduction into the blood stream. Under such conditions, a slow interaction of the drug with blood serum calcium occurs. In this regard, the Ca content does not decrease significantly, since its loss is compensated due to the mobilization of the compound from the tissues (bone, in particular) and excessive accumulations in the organs. Against the background of rapid administration of the drug, physiological mechanisms are not able to quickly eliminate the decrease in serum calcium levels. As a result, acute tetany may develop.
How else is Trilon B used?
The tool is used not only for medicinal purposes. The drug is used in analytical chemistry for the quantitative and qualitative assessment of metal salts. This becomes possible due to the ability of a substance to form complexons of different colors with ions. The Trilon B ammonia solution is used to restore batteries. This method is quick and high efficiency. Pre-charge the discharged battery, then drain the electrolyte from it and rinse with water two to three times. After it is necessary to fill in an ammonia solution, which includes two weight percent of the product and five percent of ammonia.
The duration of desulfation is about forty to sixty minutes. The process is accompanied by gas emissions and the appearance of small sprays on the surface. With severe sulfation, the procedure can be repeated. At the end of the process, gas evolution ceases. After treating the battery with Trilon B, it is recommended to flush the unit with distilled water at least three times. After it is filled with normal density electrolyte and charged. An aqueous solution of Trilon B is also used to clean pipelines. The compound is poured into the system and pumped through it for one and a half to two hours. The processing temperature is 70-80 degrees. The spent solution is drained, and the system is washed with water about three times. As a result of these actions, rust or scale deposits are eliminated. In addition, the connection protects the rubber and plastic elements of the pipeline, since the tool does not interact with them and does not change their pH. Similarly, the drug is used to cleanse the car's cooling system. As a separate agent or mixed with
washing powder, the substance is used to protect washing machines from plaque formation.