Stones in the gall bladder, disorders in its work are 5 times more common in women than in men. Remove them often offer an operational method. However, if the pebbles are small, then you can not resort to surgery, but to dissolve them with the help of special drugs. One of these medicines is Ukrliv, which will help in solving problems with the gall bladder. Next, we will examine his instructions in more detail and find out what reviews exist about him.
Who is appointed "Ukrliv"?
Studying the instructions of the drug, first of all we pay attention to who is shown its use. "Ukrliv" is assigned to the following categories of persons:
- Patients for dissolving cholesterol stones in the gallbladder with a diameter of not more than 15 mm.
- For the prevention of stone formation in the gallbladder.
- For the treatment of symptoms of primary biliary cirrhosis.
- Use in the presence of problems with the liver and in violation of the biliary system.
Even if you have confidence in your diagnosis, you still should not prescribe this drug for yourself.
How does Ukrliv affect the body?
The instruction "Ukrliva" describes how the drug acts on the body, namely:
- It creates the conditions for the dissolution of cholesterol stones.
- Reduces the synthesis of cholesterol in the liver, prevents its absorption into the intestinal wall.
- Participates in the process of formation and excretion of bile, reduces its viscosity.
- In bile, the acid content and lipase activity increase.
- The amount of cholesterol in bile is reduced.
- Enhanced gastric and pancreatic secretion.
- It has an immunomodulatory effect, improving the processes of the liver.
The instructions for use attached to the Ukrliv preparation describe in detail how the medicine acts on the internal organs through which it passes.
How does the main substance work?
The main active ingredient of Ukrliva is ursodeoxycholic acid. It quickly enters the bloodstream, penetrating the walls of the small intestine. It is also easily absorbed as a result of rapid movement in the final ileum.
The active substance is absorbed by 60-80%. Further, the extracted bile acid almost completely enters the liver with amino acids, glycine and taurine. Then it is excreted with bile. The primary clearance is 60%. Due to intestinal bacteria, partial destruction of lithium acid occurs. Absorption is only partial, and the drug is then excreted with feces. The half-life of acid occurs over 3-8 days.
Who should not take the drug?
Not shown to everyone the drug "Ukrliv", the instructions for use contain information about who is contraindicated treatment with this tool. The following patients belong to this category:
- Having special sensitivity to some components of the drug.
- If there is an acute inflammatory process of the biliary tract and gall bladder.
- The presence of radiological signs of calcification of gallstones.
- Patients suffering from frequent biliary colic attacks.
- Deviations in the contractile activity of the gallbladder.
- Cirrhosis of the liver in a decompensatory stage.
- Obstruction of the bile ducts.
- Patients in whom the gall bladder is not detected by x-ray examination.
Even having studied contraindications, a doctor's consultation is necessary before taking the drug. Health depends on it.
What side effects are there?
Be sure to describe the instruction "Ukrliva" possible side effects. These include the following:
- Abdominal pain in patients with cirrhosis.
- Some may develop urticaria.
- In rare cases, gallstones are calcified.
- Diarrhea and other digestive disorders.
- Decompensation of cirrhosis of the liver.
When treating with a drug, you need to be attentive to your state of health, you must monitor any changes in the work of organs. The dosages and recommendations of the doctor should be strictly observed.
What forms of "Ukrliva" exist?
The drug "Ukrliv" is available in two dosage forms: tablets and suspension.
The tablet form contains 250 milligrams of the drug substance. Suspension in the form of a white liquid with a lemon aroma - 200 ml per bottle. It tastes sweet, but has a bitter aftertaste. A measuring spoon is included to comply with the dosage of the drug.
Taking the drug "Ukrliv"
When taking the drug, you need to know your body weight for the correct dosage calculation. There are no age restrictions. Depending on the weight, Ukrliv tablets (250 mg) are prescribed, the instruction contains detailed information about their required quantity.
If the patient's weight is less than 50 kg, then the doctor will prescribe a suspension. It can also be taken if there are difficulties with swallowing pills and babies.
For 1 kilogram of weight per day, it is necessary to use no more than 10 grams of the drug. The weighted table looks like this:
- Up to 60 kg - 2 tablets per day.
- From 60 to 80 - 3 tablets.
- Up to 100 kg - 4 tablets.
- From 100 kg - 5 tablets per day.
If you have been prescribed Ukrliv medicine, the instruction recommends taking it once a day, while drinking plenty of water. However, at the initial stage of treatment, the recommended daily dose is allowed to be divided into several doses. It is better to take medicine before bedtime.
You should not disrupt the course of taking the drug, this will reduce its effectiveness. To obtain a good result, it is necessary that the medicine is ingested regularly. For the decay of stones, it is necessary to carry out treatment from 6 months to 2 years. If decay within 12 months is not observed, or stone calcification is noticed, the drug should be discontinued.
Ukrliv for children
It should be noted that the drug can be prescribed to newborns in case of neonatal jaundice. Only treatment should be carried out strictly under the supervision of a physician. Dosage will depend on the weight of the baby. The Ukrliv preparation should be carefully studied. 30 ml for babies syrup is enough for a course of treatment. As a rule, it is several weeks.
So, taking the syrup to a baby can be done through a syringe without a needle in order to withstand the dosage of the drug. For older children, you can use a measuring spoon (contains 5 ml of the drug). To receive Ukrliv syrup, the instructions for use for newborns suggest calculating the dosage based on the fact that 10 mg of the drug should be taken per 1 kg of baby's weight.
For other children, depending on their body weight, this dosage may be as follows:
- From 5 to 7 kg - 1.25 ml.
- From 8 to 12 kg - 2.5 ml.
- From 13 to 18 kg - 3.75 ml.
- From 19 to 25 kg - 5 ml.
- From 26 to 35 kg - 7.5 ml.
- From 36 to 50 kg - 10 ml.
This dosage should be used to treat children. It is recommended to take before bedtime, drinking plenty of water.
The instructions for use for children, as well as for adults, attached to the Ukrliv drug contain information on some of the features of the use of the drug, we will consider them further.
Features of the use of the drug
Take the drug strictly under the supervision of a doctor. It is necessary to conduct the first three months of using the drug to monitor changes in the parameters of liver function every 4 weeks, then once every 3 months. Radiography and ultrasound should preferably be done every 6 months in order to control the decay of stones and exclude their calcification; for the latter, other research methods should be used. The examination should be carried out in a standing and lying position, the general view of the gallbladder and the patency of the bile ducts are considered.
The instruction "Ukrliva" notes that the drug does not affect the reaction rate, does not cause drowsiness. Therefore, you can take it when working with mechanisms that require concentration. It is not forbidden to drive a car while taking the drug.
The suspension contains benzoic acid, which can cause irritation of the skin, eyes and mucous membranes of someone who has an increased sensitivity to this component.
In newborns, the risk of developing jaundice is increased.
"Ukrliv" for pregnant and lactating
For women of reproductive age, the use of the drug is possible if reliable contraception is observed. Pregnancy should be ruled out.
During pregnancy, in the first three months, treatment can be prescribed if the benefit of the drug is many times higher than the risk for the development of the fetus. In the next trimesters, as well as women who are breastfeeding, it is not recommended to use the drug, since its effect has not been studied.
How does Ukrliv interact with other drugs?
The instruction "Ukrliva" indicates which drugs should not be taken in conjunction with this drug. Do not take Ukrliv with substances that neutralize stomach acid. This group includes:
- "Colestyramine."
- "Kolestipol."
- Antacids that contain aluminum hydroxide or oxide of this element.
If it is necessary to take these drugs, then this should be done at least 2 hours before taking Ukrliva.
The medicine can accelerate the withdrawal of cyclosporine from the intestine, so dosage adjustment will be required. It should not be used together with drugs that increase the intake of cholesterol in bile:
- Estrogens.
- Birth control hormonal pills.
- Some medicines that lower blood cholesterol. For example, Clofibrate.
Given this, it is necessary to discuss the issue of admission with your doctor and adjust the dosage and treatment regimen.
How to store the drug "Ukrliv"?
Suspension
The drug "Ukrliv" must be stored at a temperature not exceeding 25 degrees and kept out of the reach of children. Shelf life is 2 years. After opening the suspension, the drug can be used for 4 months.
Tablets
The shelf life of Ukrliva tablets is 3 years from the date of manufacture. The temperature requirements are the same as for the suspension.
Do not use the drug after the expiration date.
Reviews about taking the drug "Ukrliv"
Some patients complain of heaviness in the stomach, nausea, heartburn, bitterness in the mouth. Examination shows usually very thick bile, the liver can not cope with the load. Assign "Ukrliv" (tablets). Instructions, reviews that were known, are justified. Relief in many came 2 weeks after the start of the dose. The heaviness and bitterness in the mouth almost disappeared. It is better to take the drug at night. Patients are satisfied with “Ukrlivom”; only high cost is not satisfied. Before use of the Ukrliv medicine, the instructions and reviews of patients who have undergone treatment with this medicine should be well studied.
So, there are many reviews of mothers of babies about taking the drug. If you carefully read the information, you can see what the 30 ml instructions for infants are provided with the Ukrliv medicine. Reviews confirm that this amount is enough for the course of treatment, the drug helps babies from jaundice well. After a few days, the baby will turn pink. No adverse reactions have been observed. It is very convenient to give the drug to a baby with a syringe. Children generally do not give up medicine, since it tastes sweet.
For older children, it is good to use a measuring spoon for syrup. The disadvantages included the fact that a very small amount of syrup is spent on the course of treatment, and finding a 30 ml bottle in pharmacies is more difficult than 200 ml. As a result, almost barely started medicine remains unused. And the shelf life is only 4 months after opening.
Given the reviews about the drug, we can say that Ukrliv is an excellent tool for eliminating problems with the gall bladder, and is also well suited for treating jaundice in children. However, do not self-medicate, it is dangerous for health, before using the drug, you must definitely get advice from a gastroenterologist.