"Mycosoral" is an antifungal agent that has antimycotic activity against yeast, dimorphic and higher fungi, adversely affects staphylococci and streptococci.
The medicine is dispensed from pharmacies in three forms:
- The tablets have a white or cream shade, a flat-cylindrical shape. They are packaged in cell packs of ten pieces.
- Ointment for external application of 2%. It is released in tubes of fifteen, twenty, thirty, forty and fifty grams.
- Shampoo 2% has a transparent viscous form from orange to yellow-orange, with a slight aroma.
The active substance of "Mycosoral" is ketoconazole.
Indications
Mikozoral tablets are prescribed in the absence of the therapeutic effect of local therapy, as well as with severe yeast damage to a large surface of smooth skin and scalp:
- Multi-colored lichen (chronic fungal infection that affects only the stratum corneum of the epidermis).
- Dermatophytosis (a fungal infectious disease from the group of mycoses, in which the skin and its derivatives are affected - hair, nails).
- Folliculitis (infection of the middle and deep sections of the hair follicle, leading to its purulent inflammation).
- Histoplasmosis (fungal infection of the lungs).
- Paracoccidioidosis (deep systemic chronic mycosis, which is characterized by a violation of the skin, internal organs with the formation of granulomas and ulcers).
- Coccidioidosis (systemic mycosis affecting the skin, subcutaneous tissue, internal organs and bones).
- Blastomycosis (systemic fungal diseases characterized by primary damage to the lungs, skin, deep damage to the tissues of the internal organs).
When else is the drug used?
"Mycosoral" indications for use has the following:
- Candidiasis of the skin (damage to the mucous cavities, skin, internal organs, provoked by yeast-like fungi of the genus Candida).
- A disease that belongs to the group of fungal diseases spreading to the skin, nails, folds of the body.
- Inguinal epidermophytosis (a chronic disease that is provoked by a fungus and affects the epidermal layer of the skin in the inguinal region).
- Pityriasis versicolor (superficial non-inflammatory progressive disease of the skin of fungal origin).
- Seborrheic dermatitis (a chronic inflammation that affects areas of the scalp and trunk that have sebaceous glands, the source of dermatitis is yeast-like fungi).
- Epidermophytia of the hands or feet (a skin disease that is provoked by a skin lesion by the fungus).
Shampoo is prescribed for the prevention and treatment of the following conditions:
- Scaly exfoliation of skin particles, usually manifested on the scalp.
- Fungal infection of the stratum corneum of the epidermis.
- Chronic skin disease, which is manifested by its focal redness and peeling.
What contraindications does the medication have?
"Mycosoral" in any form is not recommended for people with increased sensitivity to ketoconazole and other components of the drug. According to the instructions for use with Mycozoral tablets, they are not prescribed in the following conditions:
- Hereditary pathology, as a result of which the absorption processes of monosaccharides in the stomach and intestines are disrupted.
- Lactase deficiency (hereditary or acquired pathology, which is characterized by the absence or low content of the lactase enzyme).
- Lactose intolerance (a violation in the functioning of the gastrointestinal tract, which is characterized by complete or partial non-perception of lactose).
- Lactation.
- Age to three years.
- Liver disease.
- Hypochlorhydria (low hydrochloric acid in the gastric juice).
- A disease that occurs as a result of insufficient hormonal secretion of the adrenal cortex or the hypothalamic-pituitary system that regulates them.
- Alcoholism.
- The "interesting position" of a woman.
- Age over fifty for women.
Ointment - one of the forms of release of "Mycozoral" - is forbidden to apply to areas with damage to the integrity of the skin.
How to use the drug?
According to the instructions for use, the tablets "Mycozoral" are taken orally during meals. Recommended daily dosing with the frequency of use of the drug - once:
- Adults and children with a body weight of more than thirty kilograms: one tablet, in the absence of a pharmacological effect when using the indicated dosage or therapy for vaginal candidiasis, two tablets are prescribed.
- Children from three years old weighing from fifteen to thirty kilograms: half a tablet.
The average duration of therapy:
- Vaginal candidiasis - one week.
- Multi-colored lichen - one and a half weeks.
- Dermatophytosis - up to one month.
- Fungal infections of the scalp - from four to eight weeks.
How to use ointment and shampoo?
Ointment "Mycozoral" is used topically by applying to the affected skin. Frequency of use:
- Trichophytosis of smooth skin: once a day.
- Seborrheic dermatitis: once or twice a month, depending on the severity of the disease.
Recommended duration of therapy:
- Dermatomycosis of smooth skin - from three to four weeks.
- Epidermophytosis of the feet - up to six weeks.
- Inguinal epidermophytosis - up to one month.
- Pityriasis versicolor - from two to three weeks.
- Seborrheic dermatitis - up to one month.
Treatment with ointment "Mycozoral" must be carried out within three days after the complete elimination of the symptoms of infection. In the absence of positive dynamics when using the drug for up to one month, the diagnosis should be clarified.
Shampoo
It is used externally, applying for three to five minutes to damaged areas of the scalp and rinsing with water. The average frequency and duration of use:
- Inflammation caused by yeast-like fungi of the species Malassezia, scalp, dandruff of various origins: therapy - twice a week for four weeks, prevention - once every two weeks.
- With pityriasis versicolor, therapy is carried out once a day for seven days. Prevention - once a day for five days in late spring.
Adverse reactions
Pills can provoke the following negative effects:
- Drowsiness.
- Paresthesia (a disorder of sensitivity, which is characterized by sharply appearing sensations of burning, tingling, crawling ants).
- Loss of appetite.
- Abdominal pain.
- Vomiting.
- Diarrhea (regular watery stools, more than three times a day).
- Leukopenia (low white blood cell count in the general cellular composition of the blood).
- Thrombocytopenia (decreased platelet count).
- Hemolytic anemia (a disease whose hallmark is the increased destruction of red blood cells).
- Photophobia (painful sensitivity of the eyes to light, in which its exposure causes a person to have unpleasant sensations in the organs of vision).
- Oligospermia (reduction in the amount of sperm that is secreted during the production of seminal fluid from the urethra).
- Decreased libido in men.
- An erection dysfunction in which the volume of the penis of a man, his hardness and directness are insufficient for sexual intercourse.
- Urticaria (skin lesion, dermatitis of allergic origin, which is characterized by the instantaneous onset of severely itchy blisters).
- Gynecomastia (breast enlargement with hypertrophy of glands and adipose tissue).
- Alopecia (hair loss).
Ointment can provoke the appearance of the following reactions:
- Burning in places of application.
- Nettle rash.
- Contact dermatitis.
Shampoo is generally well tolerated, in addition to rare cases of oily or dry hair, local irritation and itching. What analogues does Mikozoral have? We will talk about them below.
Overdose
In case of poisoning, you need to rinse the stomach and take enterosorbent. In addition, symptomatic therapy with monitoring the patient's condition is recommended. In case of accidental ingestion of shampoo, symptomatic and supportive treatment is prescribed. To prevent aspiration, it is forbidden to provoke vomiting.
Generics
Analogs of "Mycosoral" are:
- Nizoral.
- Mikanisal.
- "Sebozol".
- Ketoconazole.
- "Dandruff."
- Oronazole.
The cost of the drug varies from 300 to 700 rubles, depending on the form of release.
Drug Comparison
Mycosoral or Nizoral - which is better? The appointment of a medication against fungal infection is carried out by a dermatologist, its independent change in the presence of individual intolerance to substances or other contraindications is prohibited.
Nizoral is an analogue of Mycozoral. The drug is available in the form of ointment and shampoo.
The composition of Nizoral includes ketoconazole, which has a similar effect with Mycozoral. If adverse reactions occur during treatment, another form of drug release may be prescribed to the patient.
"Sebozol" or "Mycozoral" - which is better?
If we compare two anti-dandruff drugs, “Sebozol” and “Mycozoral,” we can say that they are considered an exact copy of each other. The fact is that the composition of "Sebozol" includes ketoconazole - the main component of "Mycozoral."
Both of these drugs are used in cosmetology and dermatology, used against dandruff, seborrheic dermatitis, pityriasis versicolor. They help to effectively eliminate dandruff, while completely eliminating the fungus, which is considered the cause of its appearance. Both antifungal drugs have sebostatic as well as keratolytic-exfoliating effects.
The analogue of shampoo "Mikozoral" is also almost always used as a preventive measure to prevent dandruff. As for the dosage regimen and the use of these two drugs, they do not converge a little. "Mycozoral" should be used somewhat more often than "Sebozol".
Adverse reactions of both drugs are the same. A person may experience itching, burning, irritation, as well as flushing of the scalp. You can use both of these medications during pregnancy, as well as with breastfeeding. A woman can be sure that both of these drugs will not have any negative effect on the fetus.
Refuse the use of "Sebozole" and its analogue "Mycosoral" should be people who have increased sensitivity to the substances that make up their composition. The use of one of these drugs in very large dosages can contribute to the occurrence of erythema or burning of the skin.