What components does the Candiderm drug contain? The composition of this tool is presented below. Also in the materials of this article you can find information about how much the mentioned cream costs, why it is needed, whether it has contraindications, and what side effects it causes.
Composition, description, packaging
The drug “Candiderm”, the instruction of which is enclosed in a cardboard box, contains such active substances as beclomethasone dipropionate, clotrimazole and gentamicin sulfate. In addition, it contains additional components in the form of benzyl alcohol, cetomacrogol, propylene glycol, sodium dihydrogen phosphate monohydrate, methyl paraben, sodium hydrogen phosphate, propyl paraben, petroleum jelly and liquid paraffin water.
You can buy the Candiderm medication (the cream has a white color and a homogeneous structure) in aluminum tubes placed in a box.
Pharmacology of an external agent
How does the Candiderm drug work? The cream is antifungal, antimicrobial, anti-allergic and anti-inflammatory. Its effectiveness is due to the combined composition.
Consider the properties of the substances that make up the ointment, in more detail:
- Beclomethasone is a pronounced antipruritic, antiallergic, antiexudative and anti-inflammatory substance. It reduces the processes of leukocyte accumulation, releases inflammatory mediators and specific lysosomal enzymes, and also inhibits phagocytosis, prevents the formation of puffiness and reduces vascular tissue permeability.
- Clotrimazole is an antifungal component. It reduces the synthesis of ergosterol, which is an integral part of fungal cells.
- Gentamicin is an antibiotic element. It belongs to the aminoglycoside group. This substance is capable of exerting a bactericidal effect. Also, this component effectively suppresses the activity of staphylococci, Klebsiella, pseudomonas, Proteus, enterobacteria, streptococci and Escherichia.
Kinetic properties of the drug
Candiderm cream, the price of which is indicated below, has not been investigated for pharmacokinetic parameters. This is due to the fact that the composition of the drug in question includes several active substances.
Indications for external use
In what cases should you use the drug "Candiderm"? The cream should be prescribed only by an experienced dermatologist for the following indications:
- eczema, epidermophytosis of the feet, allergic dermatosis;
- phleboderma, lichen planus, atopic dermatitis;
- dermatosis with a secondary infection, diffuse form of neurodermatitis;
- dermatomycosis (including the inguinal region), anogenital itching, dermatitis that occurred after insect bites.
Contraindications
What diseases can you not use the drug "Candiderm" (ointment)? The instructions that came with this tool indicate the following prohibitions:
- trophic wounds on the skin, chicken pox;
- rosacea, individual hypersensitivity;
- acne vulgaris, open wound surfaces;
- tuberculosis of the skin, post-vaccination reactions on the skin;
- viral skin lesions and syphilitic reactions.
The drug "Candiderm" (ointment): instructions
Do you know how to use the medication in question? According to the instructions, the cream must be applied to the affected skin twice a day. It is advisable to carry out these procedures before bedtime and after waking up.
The duration of use of this medication depends on the individual characteristics of the person, the tolerance of the ointment and the overall effectiveness of the therapy.
As practice shows, after a 4-week treatment, the patient may experience the first adverse reactions.
Use in childhood
Are Candiderm prescribed for children? In pediatric practice, this drug is used only for indications. It is prescribed to adolescents from 16 years old. If required, then by decision of the doctor, the cream can be applied at the age of 7-16 years.
Adverse Events
Does the drug “Candiderm” cause adverse reactions? The cream is relatively well tolerated by patients. However, the instruction indicates that prolonged use of this tool can cause inhibition of the adrenal cortex.
If you use the drug according to the recommendations of doctors, then negative effects are extremely rare. However, they are only temporary, as well as mild.
So what adverse reactions does the drug in question cause? Against the background of its use, you may experience:
- dry skin, contact dermatitis, swelling, hyperemia;
- striae, peeling, maceration, furunculosis, urticaria;
- hypertrichosis, telangiectasia, pyoderma, perioral dermatitis ;
- hypopigmentation, burning sensation, folliculitis, prickly heat;
- atrophic changes on the skin, acne eruptions steroid.
Overdose of an external agent
When using large doses of the drug on large areas of the skin, the following signs of an overdose can be observed:
- glucosuria, weight gain, increased blood pressure;
- hypokalemia, manifestations of hypercorticism.
With such symptoms, the patient is corrected electrolyte balance, and also conduct syndromic therapy.
Recommendations for the use of ointment
The ointment in question should not be used to treat eye diseases. Also, this drug should not be applied to the skin located around the eyes.
If bacterial or fungal resistance occurs, the cream is canceled.
Occlusive dressings increase the therapeutic effectiveness of the drug.
Cross-resistance may develop during treatment with aminoglycosides.
The use of this product with dressings leads to increased transdermal absorption of its active elements (beclomethasone and gentamicin). Such an effect can contribute to the appearance of systemic adverse reactions.
In pediatrics, Candiderm cream is prescribed only according to indications and is used under medical supervision.
The use of dressings with ointment on large areas of the skin leads to the suppression of the pituitary-hypothalamic-adrenal system.
Price and analogues of ointment
How much does Candiderm cream cost? The price of this ointment is 440-470 rubles. Such a high cost of the drug confuses many patients. In this regard, they prefer to replace it with cheaper analogues. Among them, the following products are especially popular: Belogen, Betaderm, Betagenot.
Testimonials from doctors and patients
Experts say that the Candiderm cream is a unique product for external use that has antifungal, antipruritic and anti-inflammatory properties.
Doctors leave only positive reviews about this medication. The drug in question copes well with the task and is actively used in dermatological practice.
Also, positive feedback about the Candiderm cream is left by the patients. They report that this remedy allows you to quickly eliminate the unwanted symptoms of most skin diseases. Moreover, this drug practically does not cause side effects.
Of the minuses of this medication, its high cost and the presence of a large number of contraindications can be distinguished.