"Nimesil" refers to a new generation of drugs that have relatively few side effects and contraindications. With symptomatic treatment, it turns out to be an indispensable assistant. How and why to use this drug and what you need to know when combining it with other drugs? About this in the article below.
Pharmacological properties
Non-steroidal anti-inflammatory drug belonging to the class of sulfonamides, "Nimesil" has the main active ingredient nimesulide. Its use is relevant in the fight against pain, inflammation, fever. After taking the drug, the effect can be felt after 20-30 minutes, which then lasts for about 6 hours.
The maximum concentration in the blood is reached after 2-3 hours. About 50% of nimesulide is excreted in the urine, about 29% - with feces.
The powder tastes sweet-sour due to the fact that it contains sucrose, citric acid and orange flavor. This should be considered for those who have an allergic disease.
Release form
In the pharmacy network, the drug can be found in the form of granular powder, which has a light yellow color and is packed in a paper sachet. When calculating the course of admission, it is necessary to take into account the number of sachets in the box. They can be 9, 15 or 30 pieces in a cardboard box. The total weight of dry powder in one sachet is 2 g.
The remaining forms, such as tablets (including for resorption and for children), suspensions, are found in analogues that have the same active substance - nimesulide. If there are contraindications, the instruction to "Nimesil" allows you to choose the necessary form of a similar drug, but in a different form.
Indications for use
The drug has effectively established itself in the treatment of the following diseases:
- cold;
- pain in the lower back, back, dental, muscle, joint, with osteoporosis;
- algodismenorea.
If there are no contraindications to Nimesil, then apply it for dislocation of joints, sprains. The drug can also be prescribed to those who suffer from mild renal failure. If we talk about old age, then a consultation with a doctor is necessary, since the compatibility of this drug with those that patients can take at the moment should be determined. When it comes to symptomatic treatment, the duration of admission is at least 15 days.
The drug has a positive effect at a low temperature. If an ache in the body is felt, then two symptoms are suppressed by one remedy.
Contraindications
According to the instructions for use of "Nimesil", a contraindication is children's age up to 12 years. True, this is not the only reason for refusing to take the drug. Naturally, the main recommendation for prescribing the drug should come from the attending physician. However, it is worth noting separately the list of contraindications for the use of Nimesil:
- simultaneous administration of analgesic drugs;
- liver disease and heart disease;
- temperature above 38 degrees with SARS and flu;
- taking non-steroidal drugs for a long time;
- ulcers of the duodenum, gastrointestinal tract, ulcerative colitis;
- taking drugs and alcohol;
- type 2 diabetes mellitus.
Also, some somatic diseases and aspirin asthma are a contraindication for the use of the drug. During pregnancy planning, a woman is not recommended to use Nimesil, as it helps to reduce fertility. It is worth refraining from taking it or replacing it with another drug.
Patients suffering from renal failure should use this medication with caution. It is advisable to consult with your doctor in advance, as adjustments to medication may be required.
How and in what quantities to take
Dosage recommendations are contained in the instructions for use of Nimesil powder. Reviews of contraindications should also be carefully studied before taking the drug. You can not take the product in dry form, it should first be completely dissolved in half a glass of warm boiled water. This will allow the medicine to be absorbed faster. Intensity of reception - 2 times a day for 1 sachet. The general course of treatment should not exceed 15 days.
The prepared solution is not recommended to be stored. It should be taken immediately, as the powder was diluted, preferably after a meal.
Side effects
The presence of "Nimesil" contraindications and side effects does not mean that the drug is bad. This means that it is well studied and helps prevent the onset of unpleasant consequences for the human body. It should be borne in mind that a negative effect on the hematopoietic system is possible, since there is a risk of developing hemorrhagic syndrome, anemia, eosinophilia, thrombocytopenia, thrombocytopenic purpura. From the side of the nervous system - dizziness, nightmares, headache, nervousness, drowsiness and others.
There is a chance of developing an allergic reaction: itching, dermatitis, excessive sweating, urticaria. Long-term use of Nimesil may adversely affect the digestive system - diarrhea, flatulence, nausea, gastritis; on the part of the respiratory system - exacerbation of bronchial asthma, bronchospasm, shortness of breath. Side effects that affect the functioning of the cardiovascular system - hot flashes, tachycardia, arterial hypertension, as well as the genitourinary system - hematuria, oliguria, urinary retention, interstitial nephritis are also noted. In some cases, you may notice a visual impairment, but this is extremely rare.
In the case when the patient has a hereditary disease associated with fructose intolerance, sucrose-isomaltose deficiency, it is necessary to refrain from using Nimesil. While driving, you should control your condition, as the drug can affect the reaction and attention. The main rule for detecting side effects is to stop taking the drug and consult a doctor to adjust the treatment regimen.
Drug overdose
If the contraindications and side effects of Nimesil are studied in advance, an overdose can be avoided. But since not everyone reads the instructions, it is worth describing its symptoms in more detail:
- drowsiness, apathy;
- nausea, vomiting, gastric bleeding (in rare cases);
- increase in blood pressure;
- difficulty breathing
- very rarely anaphylactic shock;
- pain in the stomach;
- coma (extremely rare).
To avoid unpleasant consequences, it is important to follow the rules of admission and know the contraindications to Nimesil. It is recommended to take the drug in small quantities and infrequently. Emergency help with an overdose is effective if no more than 4 hours have passed. In this case, it is necessary to cause a gag reflex to cleanse the contents of the stomach.
How to use during pregnancy and lactation
Since the main active ingredient of the drug suppresses the synthesis of prostaglandins, in the instructions for use of the Nimesil powder contraindications are pregnancy and the period of breastfeeding. There is a risk of adverse effects on fetal development. The action of nimesulide can lead to impaired renal function, the risk of premature closure of the ductus arteriosus, bleeding, and the development of peripheral edema.
Interaction with other drugs
"Nimesil" is not contraindicated while taking furosemide, as well as drugs that are aimed at reducing blood coagulation. However, extreme caution should be exercised and consult a doctor first. This is especially true for those who suffer from heart and kidney diseases.
If Methotrexate is prescribed, then their simultaneous use can aggravate the general well-being and lead to the development of side effects. This is expressed in an increase in the toxic properties of Methotrexate, while the drug is prescribed with Nimesil. Separately, you need to pay attention to the time of admission - it is not recommended to use Nimesil less than a day before or after using Methotrexate.
Before buying Nimesil, you need to consult those who are already taking anti-inflammatory and pain medication. This can also include diuretics and those dosage forms that reduce blood pressure. It is not recommended to simultaneously use the drug with medicines, which include paracetamol, analgesics.
Analogues of the drug "Nimesil"
There are not many analogues in the composition of Nimesil. In the instructions for use, you can find information about the main active substance, focusing on it, you can choose drugs with the same component. These include Nimedar powder, it is almost identical to Nimesil. They are distinguished only by the country of origin and price.
Another analogue of the drug is Prolide and Nimegesic in the form of tablets. It is worth paying attention to a large number of contraindications. “Nimesil” in this case is in a better position.
The Swiss counterpart of Affida Fort is also considered a full-fledged substitute for this drug both in terms of the main active ingredient and in the dosage form itself. Therefore, in the absence of choice, you can safely get it.
The main active ingredient nimesulide is also found in an analogue of the drug called Nise. This is a gel that is used for inflammatory diseases. Effective when it is necessary to relieve swelling, muscle pain. It is also available in the form of tablets and can serve as a good analogue when the action of the powder is not enough.
Product Usage Reviews
Those who choose the drug among others, first of all pay attention to contraindications. Powder "Nimesil", despite the fact that it has a rather large list of them, refers to proven and reliable means in the fight against pain. Users note its effectiveness in toothache, as well as during menstrual bleeding and with injuries.
Due to the cost of the whole package, especially if it contains 30 bags, a unit sale of the drug is allowed in the pharmacy network. This allows many to choose this drug for an emergency.
Doctors often prescribe Nimesil as a treatment for acute bouts of pain. For example, after dental procedures to reduce the risk of inflammation and swelling. Therefore, it is recommended to keep this drug in the medicine cabinet.
In medical practice, it is not recommended to use this tool for acute surgical pathologies, suspected flu. The reviews of doctors in this case agree that trying to hide a symptom of pain, we can allow complications that threaten to lead to serious consequences.
Parents of teenagers prefer to give their children a diluted powder rather than a pill. Moreover, the first one has a pleasant taste, is quickly absorbed, and after half an hour you can feel relief.