Do you know what a drug like Phlosterone is? Reviews of experts say that this is a universal remedy that can be used in various pathological conditions.
About what properties the mentioned medication has, in what form it can be purchased and how to use it, we will tell in the presented article.
Packaging, composition and form of release
Where is the drug "Phlosterone" sold? Reviews of people report that this medication can be purchased at any pharmacy. Also, some patients order it via the Internet.
This product contains active ingredients such as betamethasone disodium phosphate and betamethasone dipropionate. In addition, the drug contains auxiliary elements in the form of sodium chloride, sodium carmellose, polysorbate 80, sodium edetate, methyl paraben, benzyl alcohol, concentrated hydrochloric acid, propyl paraben, sodium hydrogen phosphate dihydrate, purified water and polyethylene glycol.
The medicine "Phlosterone", reviews of which are presented below, is produced in the form of a suspension for injection. It is available in ampoules (1 ml each) in contour packs.
Pharmacodynamics
How does the drug "Phlosterone"? Instructions for use (reviews of specialists about this tool are only positive) reports that the active substances of the mentioned drugs are glucocorticosteroids (that is, a synthetic substitute for adrenal hormones). They have immunosuppressive, anti-rheumatic and anti-inflammatory properties.
Betamethasone affects glucose homeostasis, energy metabolism and nutritional hormone from the adenohypophysis.
To date, the principle of action of glucocorticosteroids has not been fully studied. However, there is an opinion that the process of their impact is carried out at the cellular level. Experts believe that there are 2 receptor systems in the cytoplasm of the cell, and betamethasone directly affects the participation of special GCS receptors. In turn, mineralocorticoid receptors contribute to the regulation of sodium-potassium metabolism and water-electrolyte balance.
Fat-soluble substances are called corticosteroids. They can easily penetrate cell membranes into the target cell.
Thus, the effect of the drug we are considering is based on special biochemical processes that occur at the molecular level.
Pharmacokinetics
Betamethasone dipropionate is absorbed slowly, but it provides a fairly long-lasting effect. Depending on the method of administration of the drug, it can achieve a general or local effect.
The maximum concentration of the drug after intra-articular administration is observed after about 30 minutes. In blood plasma, the drug binds to proteins quite quickly. It easily penetrates the histohematological barriers, including the placental.
The metabolism of the drug is carried out in the liver with the formation of inactive metabolites. Excretion of active substances occurs through the kidneys, as well as together with bile and partially with breast milk.
Indications
When are patients prescribed “Phlosterone” injections? Reviews of doctors say that this is a universal drug that can be used to treat various diseases. According to the instructions, this medication is used for:
- cerebral edema;
- blood transfusion, traumatic, burn, anaphylactic, surgical, cardiogenic and toxic shocks;
- systemic connective tissue diseases (for example, with lupus erythematosus, thyrotoxic crisis, hepatic coma, rheumatoid arthritis);
- treatment of severe bronchial asthma;
- anaphylactoid reactions ;
- to prevent inflammation and scarring after exposure to cauterizing fluids.
Can “Phlosterone” be used for allergies? Reviews of experts report that this drug is very effective in allergic reactions. Therefore, it is often prescribed for:
- bronchial asthma, chronic or seasonal rhinitis;
- psoriasis, contact atopic dermatitis and keloid;
- collagenoses;
- extraarticular rheumatism, lumbago, tendosynitis, myositis, synovitis, post-traumatic osteoarthritis, epicondylitis, fibrositis;
- insect bites;
- all kinds of allergic reactions;
- ulcerative colitis.
Contraindications
When should you not use the drug “Phlosterone” (instructions, reviews about this medication will be presented later)? It is not prescribed for:
- osteoporosis, gastric ulcer, tuberculosis, diverticulitis, glaucoma;
- Itsenko-Cushing's syndrome, thrombophlebitis, acute viral, fungal or bacterial infections, diabetes mellitus;
- heavy operations and injuries, before and after vaccination (within two weeks);
- thrombocytopenic idiopathic purpura (intramuscularly);
- lack of inflammation in the joints;
- bone deformities and joint destruction, joint instability;
- congenital bleeding or caused by the use of anticoagulants;
- lactating women, children under three years of age, hypersensitivity.
Medication "Floosteron": instructions for use
Patient reviews about this medicine are very mixed.
How should I use this medication?
To affect the patient’s body systemically, the medication is administered intramuscularly. Injections are done in the gluteus muscle (deep) in 0.1-0.2 ml every 2-4 weeks.
How is “Phlosterone” prescribed for allergies? Reviews of experts say that such a drug is often used in case of acute allergic reactions. In this case, injections are also made intramuscularly in an amount of 1-2 ml (once).
With topical use of the drug, the dosage can vary significantly. As a rule, it is 0.25-2 ml.
With psoriasis, neurodermatitis, eczema and other skin diseases, the medication is administered intradermally.
If required, the drug can be mixed with procaine or lidocaine for pain relief.
For babies 3-5 years old, the initial dose of this medicine is 0.3 ml, and for children 6-12 years old - 0.6 ml.
The drug "Phlosterone": reviews
Analyzing the reviews of specialists about the tool in question, we can safely conclude that this drug is very effective. According to doctors, this medicine is used for fairly serious diseases of the brain, connective tissue, anaphylactoid reactions, etc.
As for patients, they do not always leave positive feedback about the “Flosterone” suspension. Reviews of people say that this medication very often causes adverse reactions. These include dizziness, general malaise, thinning of the skin, weight gain, and more.