The drug "Ulkavis" (reviews note that the medicine helps with gastritis, the improvement is noticeable on the 2-3rd day of its use) is an antiulcer drug. It has bactericidal activity against Helicobacter pylori. Effective in many diseases of the gastrointestinal tract. Covers the film with the mucous membrane of the stomach, which contributes to its rapid recovery.
The composition and form of the drug
The drug āUlkavisā is produced in the form of tablets. The active substance is bismuth tripotassium dicitrate in an amount of 303.03 mg, which corresponds to 120 mg of bismuth oxide. Additional components in the composition of the tablets are:
- corn starch;
- povidone K30;
- potassium polycryline;
- macrogol 6000;
- magnesium stearate.
The pill shell consists of the transparent component Opadry II, which includes elements such as polyvinyl alcohol and macrogol 4000. In addition to this substance, the shell also contains talc and titanium dioxide.
Ulkavis tablets (reviews note that the drug works quickly and effectively) have a round shape and a white shell. They have a bevel. Enclosed in an aluminum blister for fourteen pieces. A packing box can contain two, four or eight blisters.
The drug is produced in Slovenia by the Krka company. It should be stored in a dry, cool and protected from the sun at a temperature of not more than + 25 Ā° C. The shelf life of the pills is two years from the date of manufacture.
The medicine is dispensed without a doctorās prescription. It costs about 300 rubles for 50 tablets. The price of 112 capsules is 500 rubles.
On the pharmacological effects of the drug
The anti-ulcer agent āUlkavisā (reviews claim that tablets are cheaper than the popular analogue āDe-Nolā) has a pronounced bactericidal activity against Helicobacter pylori. It is endowed with astringent and anti-inflammatory properties.
Penetrating into the acidic environment of the stomach, insoluble citrate and bismuth oxychloride precipitate there, creating a special protein substrate. It is a protective film that forms on the surface of erosion and ulcers. The drug increases the synthesis of PGE, as well as the amount of mucus and the production of bicarbonate. Activates the activity of cytoprotective mechanisms. Increases the resistance of the gastrointestinal mucosa to the influence of hydrochloric acid, pepsin, various enzymes and salts. A similar action of the drug leads to the creation of a reserve of epidermal growth factor in the area of āāthe defect. Reduces pepsin activity.
Bismuth subcitrate is practically not absorbed from the gastrointestinal apparatus. It comes out with feces. A small fraction of bismuth enters the bloodstream and is subsequently excreted by the kidneys.
Indications and contraindications
It is recommended to use the Ulkavis medication (tablets) only as prescribed by the doctor. Indication for the appointment of the drug is a stomach ulcer and duodenal ulcer, which is in the acute stage, including that caused by Helicobacter pylori. A medicine is used for gastroduodenitis and chronic gastritis, when the development of the disease has reached an exacerbation phase and there is the bacterium Helicobacter pylori. Prescribe pills for irritable bowel syndrome, accompanied by diarrhea. The prescription for the use of the drug is functional dyspepsia, which is not related to organic pathologies of the gastrointestinal tract.
The drug "Ulkavis" (reviews note that with a stomach ulcer, the drug helps in the first week of administration, the pain goes away, and the person begins to feel completely healthy) is not prescribed for individual intolerance to the components contained in the medication. It is forbidden to use the remedy for kidney failure, which is in a difficult stage of development, when the level of Cl creatinine is less than 30 ml / min. The medicine is contraindicated in pregnancy and lactation. You can not prescribe these tablets to children whose age has not reached four years.
During treatment with "Ulkavis" should take into account the possibility of side effects. Among them are gag reflex, nausea, diarrhea, constipation. All these symptoms are temporary and immediately disappear after drug withdrawal.
Taking pills can cause skin rashes, itching. With prolonged use and large doses, there is a risk of encephalopathy, which is associated with a high bismuth content in the central nervous system.
With the improper use of the medication, overdose symptoms may appear in which the kidneys are disturbed. All phenomena are completely reversible and disappear after cessation of the use of the drug.
Ulkavis tablets: application instruction
Pills are taken orally half an hour before meals, washed down with water and without chewing.
Adults and children over the age of twelve are prescribed one tablet four times a day. You can take the medicine two tablets twice a day.
For children from eight to twelve years of age, the medication is prescribed one pill twice a day. At the age of four to eight years, the daily dosage is taken at the rate of 8 mg of the drug per kilogram of the childās weight.
The therapeutic course lasts 1-2 months. In the next two months, it is forbidden to take medicines containing bismuth.
With the eradication of Helicobacter pylori, combined treatment is performed. Here, Ulkavis tablets (the instructions for use are attached to the drug and should be carefully studied before use) are prescribed together with antibacterial medicines characterized by anti-Helicobacter pylori activity.
Thirty minutes before and after using Ulkavis, you canāt take other medicines, food or any liquid, this will reduce the effectiveness of the medication.
If Ulkavis tablets will be used together with tetracycline, then the absorption of the last drug will be reduced.
It is not recommended to use this medication for more than two months. Do not exceed the dosage established for children and adults. When treating with Ulkavis, it is forbidden to use medicines containing bismuth. After the treatment course, if the drug was taken in the recommended doses, the content of the active substance in the blood will be no more than 3-58 mcg / l. Bismuth poisoning occurs at a plasma concentration of 100 Ī¼g / L.
The drug āUlkavisā (tablets) can cause darkening of feces. The instruction notes that this is due to the formation of bismuth sulfite. In rare cases, for the same reason, a darkening of the tongue can be observed.
Doctors reviews
It is strongly advised to adhere to the doses prescribed by the doctor when using the drug "Ulkavis" instruction. Reviews of doctors note that the drug has an affordable price and excellent healing properties. Effective against Helicobacter pylori. It has wound healing and antibacterial properties. It has proven itself in the treatment of gastritis and ulcers. Bismuth salts contained in the preparation envelop the sore spots and help them heal. In combination with a diet gives excellent results. Appeared relatively recently, but has already managed to prove itself from the best side. It is a complete analogue of the famous De Nola, but, unlike the latter, is cheaper.
Doctors say that the drug rarely causes side effects and is well tolerated by patients. Despite the fact that the medicine gives a quick effect, doctors are advised to undergo a full therapeutic course and take pills for at least a month.
Patients' opinion about the medicine
Warns that you need to familiarize yourself with contraindications before taking the drug "Ulkavis", instructions for use. Reviews of people about this medication in most cases are positive.
Patients note that the medicine acts quickly and effectively. Usually, symptom relief occurs at the end of the first week of treatment of gastritis, ulcers and other pathologies of the gastrointestinal tract. Patients claim that pills help quickly remove pain, heartburn, nausea, and bad breath. The medicine relieves exacerbation of gastritis and ulcers. Often used in the complex treatment of Helicobacter pylori. The medicine covers the formed ulcers with a film and helps them heal. Gently restores the mucosa of the gastrointestinal tract.
The drug is convenient to take - two tablets twice a day, washed down with water. For diseases of the stomach and intestines, drinking āUlkavisā should be at least a month. Some doctors recommend fixing the result for two months continuously. The appointment depends on the diagnosis and stage of development of the disease.
This medicine appeared on the market relatively recently, and therefore many patients treat it with distrust. First they buy a small package of medicine, and after positive changes they buy a large one.
Often, āUlkavisā is compared with the medicine āDe-Nolā. The last tool has already proven itself. It has long been used effectively in the treatment of gastrointestinal diseases. Therefore, the replacement of āDe Nolaā with āUlkavisā often causes a lot of doubts in patients.
There are no negative reviews about this drug. In isolated cases, nausea and diarrhea were observed in patients treated with the medication. Symptoms after drug withdrawal quickly disappeared.
Similar medicines
It is recommended to take the medicine āUlkavisā instruction only as prescribed by the doctor. Analogs to this drug are sold in every pharmacy and, if necessary, will help replace it.
The most popular substitute for Ulkavis is De Nol. Both drugs contain bismuth salts. Analogs for this medication can be āNovobismolā, āEscapeā, āVentrisolā, āPilocidā, āTribimolā, āVikairā.
If it caused side effects or the Ulkavis preparation didnāt come up for any reason, it is recommended that the instructions for use be carefully selected and only after consultation with a doctor. After all, only a doctor, assessing the patientās health status, will help make the right choice.
Analog "De Nol"
The drug "De-Nol" is the most expensive and popular analogue of the drug "Ulkavis." Instructions "De Nola" fully describes the principle of action of the tablets, as well as the way they are used. Like the previous preparation, De-Nol contains tripotassium dicitrate in bismuth. The medicine protects the gastric mucosa from damage, restores it. Another medication reduces the activity of peptin (a gastric enzyme) and stimulates blood circulation in the mucous membrane.
The drug has antibacterial activity against the bacterium Helicobacter pylori, which often provokes the appearance of gastritis and ulcers. It is soluble, as a result of which it is able to penetrate deeply into the mucous layers of the stomach.
The drug should not be taken by children, as well as pregnant and lactating women. The therapeutic course lasts 1-2 months. Adults should take four tablets per day.
The drug is manufactured in the Netherlands by Astellas. The cost of 8 tablets is about 60 rubles, 56 tablets - 450-500, 112 pills - 800-850 rubles.
Patient reviews called "De Nol" the best anti-ulcer drug. It is noted that the drug acts quickly and effectively, and improvements are noticeable after several days of using the tablets. The medicine is well tolerated by patients and rarely causes side effects. It is used in complex therapy in the treatment of Helicobacter pylori. Some patients consider the price of the medicine too high, so they often pay attention to its analogues.
Novobismol - the Russian analogue of Ulkavis
Novobismol tablets are the Russian analogue of the Ulkavis drug. The medicine instruction recommends using for ulcers and gastritis, which are caused by the bacterium Helicobacter pylori. Typically, a medication is prescribed during an exacerbation of these diseases. Another indication for the use of tablets is irritable bowel syndrome, which is accompanied by diarrhea, and functional dyspepsia.
The drug is indicated for adults and children from four years old in a dose of two to four tablets per day. The course of treatment lasts about 1-2 months. If taken incorrectly, it can cause side effects. The medicine is not recommended for more than eight weeks. When applied, it is possible to stain the stool and tongue in black.
The drug is produced by Pharmproject. The cost of 56 tablets is 300 rubles, and 120 - 600 rubles.
Patients note the effectiveness of this drug. They say that it rarely provokes the appearance of negative reactions. It can be used in conjunction with other medicines in the treatment of diseases caused by the bacterium Helicobacter pylori. The drug quickly relieves the symptoms of ulcers and gastritis. Easy to use. Not every pharmacy sells - this is perhaps its main drawback. Patients do not note negative phenomena when using the medication.
Cheap substitute "Vicair"
The medicine āUlkavisā recommends taking the instructions for use only as directed by a doctor. "Vicair" is the cheapest analogue of this drug. It is a combination drug. In its composition, in addition to bismuth nitrate, there is magnesium carbonate , sodium bicarbonate, as well as rhizome of calamus and buckthorn bark. The medicine has astringent, laxative, antispasmodic and antacid properties.
Tablets are prescribed for stomach ulcers and duodenal ulcers. An effective medication for gastritis. The drug is taken 1-2 tablets three times a day. The therapeutic course lasts 1-2 months.
The drug is produced in Russia by the companies "Dalhimpharm", "Pharmstandard-Tomsk" and "Pharmstandard". The cost of 10 tablets is 25-30 rubles.
Reviews note that the medicine relieves pain in gastritis and ulcers on the third day of use, and on the 7-10th day the improvements become so obvious that a person completely forgets about the disease. The drug weakens, so it is not suitable for people prone to diarrhea. Some patients noted an increase in appetite after taking pills and a digestive disorder. In general, this medicine has proven itself well and will be able to replace Ulkavis tablets if necessary.