In type 1 diabetes, the patient can use fast-acting (instant), short, medium, prolonged and pre-mixed insulin. Which one to prescribe for the optimal treatment regimen depends on the individual characteristics of the body. If you need ultrashort insulin , Glulisin is used.
An injection solution called "Insulin Glulisin" is purchased in pharmacies by those patients who suffer from diabetes. This drug is required for people to lower sugar levels, and in addition, for the treatment of this disease. This is, first of all, short insulin. It is an integral component of other drugs for diabetics. This substance has a pronounced hypoglycemic effect.
This is an analogue of human insulin, which is similar in principle to this hormone. But by its nature, it acts faster and has a short effect.
Dosage and administration
This solution is used subcutaneously 15 minutes before eating. Dosage is selected individually.
It is possible to use using a pump-action system. The daily human need for insulin is usually 0.5 units. per kilo of mass: of these, two-thirds are insulin immediately before taking food. And one third is in the background insulin (basal).
Brand Names
“Insulin glulisin” in the pharmaceutical market has two more trade names. Many have heard it.
These are the Apidra and Apidra SoloStar medicines.
The drug "Apidra" ("Epidera"): description
Let's consider this drug in more detail.
Apidra insulin is used to treat diabetes in children from six years of age, and it is also used for adults. The preparation contains 3.49 milligrams of the main substance. This component can be compared with 100 IU (International Units) of the human hormone. Auxiliary ingredients include injection water along with m-cresol, chloride and sodium hydroxide, concentrated hydrochloric acid, trometamol and polysorbate.
Apidra insulin is sold in a 10 milliliter bottle or in 3 milliliter cartridges. The first option is packed in a cardboard box, and the second is placed in contour packaging with cells. In the latter case, there are five cartridges that are charged into a special pen (that is, a syringe), which is called "OptiPen" (this is such a disposable pen).
The manufacturer also makes a separate OptiKlik cartridge system. Absolutely in all containers there is a clear liquid that has no color.
Apidra SoloStar
The active component in it is present in exactly the same amount as in the previous option considered. "Insulin glulisin" with the trade name "Apollo brand SoloStar" has the following contraindications:
- The presence in patients of hypoglycemia and hypersensitivity of the body to the base or auxiliary substance of this medication.
- The period of childhood is up to six years.
Apidra and Apidra Solostar medicines can be purchased at any pharmacy network.
The subtleties of the use of these medications
"Insulin glulisin" is almost identical to human. The only exception is the duration of exposure, which is much shorter. It is enough to give the patient only one injection of this drug, as after 15 minutes he will certainly feel significant relief in his condition.
Input methods may vary. For example, this agent is injected subcutaneously into a specific area and then, with the use of an insulin pump, the procedure ends. Infusion can be performed without interruption, which is done in the fatty tissue directly under the skin.
The procedure should be done either before a meal, or after, but not immediately. Subcutaneous injections are best done in the abdominal region, but are also allowed in the shoulder, and the thigh is still suitable. But the infusion can be done exclusively in the abdomen. Only a doctor can prescribe a treatment regimen. This medication is used to administer insulin with a long or medium duration.
It is allowed to combine the input of "Insulin glulisin" with tablets (the use of hypoglycemic drugs). The dosage and selection of the drug is determined by the attending physician, since the patient has no right to make a choice on his own. The fact is that this is fraught with extremely negative consequences. Among the important directions for use can be found and recommendations for the area of administration of the drug. It is important to prevent damage to blood vessels.
What else is the instructions for use with Insulin Glulizin?
Special instructions for the use of medicines
Intravenous administration of the drug is carried out only in specialized endocrinological departments. When using insulin aspart in pumps for subcutaneous administration, mixing this drug with any other solutions is prohibited.
Store used syringe pens only at room temperature. An unused syringe pen must be kept in the refrigerator. The drug should be administered only after thorough mixing of the contents in the syringe until a whitish, uniform color.
Intense physical activity, as well as concomitant infectious and inflammatory processes, will require additional amounts of insulin.
At the beginning of therapy, vehicle driving is not recommended, and in addition, work with moving mechanisms due to visual impairment. Against the background of constant administration of the drug, caution must be exercised in connection with the possible occurrence of hypoglycemia.
Side effects of the application
The central nervous system, just like the peripheral system, can respond to Insulin Glulisine by quickly stabilizing the blood glucose level at the beginning of therapy. The onset of acute pain neuropathy is possible, which may differ in a transient nature. Among dermatological reactions, it is worth mentioning lipodystrophy at the injection site of this medication.
The sensory organs can react with impaired refraction, and in addition, a decrease in visual acuity, which will also be associated with accelerated stabilization of the presence of glucose in the blood at the beginning of treatment. This condition may be transient in nature. As part of the use of this tool, allergic reactions are not excluded.
Overdose
In case of overdose, patients may experience hypoglycemia. Against the background of the development of a hypoglycemic coma, up to 100 milliliters of a 40% dextrose solution are injected intravenously until a person can get out of his coma.