The drug "Femoston 2/10" is a drug for hormone replacement treatment. It is used in the treatment of various natural changes in the female body that are caused by the onset of menopause or surgical castration. This medication provides the supply of certain sex hormones, which during menopause or after surgery to remove the ovaries are not produced in adipose tissue in sufficient quantities, which supports the normal functioning and condition of all organs and systems. The drug eliminates all kinds of disorders that are caused by a deficiency of sex hormones in the body, and eliminates vegetative, sexual and psychoemotional disorders, prevents the development of osteoporosis and coronary heart disease.
Forms of release and composition of the medication
Currently, this medicine is available in three main varieties - "Femoston 1/10" and "2/10" and "Femoston 1/5". All these varieties of the drug are available in tablets for oral administration, and differ in the dosage of the main component.
The composition of the pharmacological drug "Femoston 2/10" as an active substance includes estrogen hormone (estradiol) and progesterone hormone (dydrogesterone) in a certain dosage. The medicine is available in packs of 28 tablets, and you can observe two of their varieties - pink and yellow. Both types of these tablets are available in equal quantities, that is, in one package contains 14 pieces of pink, 14 pieces of yellow.
One pink tablet contains 2 mg of estradiol, and a yellow tablet contains 2 mg of estradiol and 10 mg of didrogesterone. All tablets of the drug have the same dimensions, a round biconvex shape, as well as the numbers "379" on one side. Reviews about "Femoston 2/10" when planning pregnancy are abundant.
As additional components that play an auxiliary role, all tablets of the three varieties of the drug contain the same substances, which are:
- hypromellose;
- magnesium stearate;
- colloidal silicon dioxide;
- lactose monohydrate;
- titanium dioxide;
- polyethylene glycol;
- talc;
- iron oxide is black, yellow and red, which is used by staining tablets. This is confirmed by the "Femoston 2/10" instructions for use.
pharmachologic effect
All types of the drug have similar therapeutic properties, and a variety of dosages of active hormonal substances make it possible for each patient to choose the optimal treatment option that best suits her. "Femoston 2/10" with menopause is also used.
It is considered to be an effective combined, modern, low-dose hormonal medication, the therapeutic effect of which is due to its hydroxyterone and estradiol.
Estradiol is absolutely identical to natural, which is produced during the normal functioning of a woman's ovaries. Therefore, the medicine is designed to make up for the estrogen deficiency in the body when it is not sufficiently developed when menopause occurs or in the complete absence of ovaries with castration syndrome. This hormone in women during menopause or after surgery to remove the ovaries ensures smoothness and elasticity of the skin, its slower aging, slows down the process of hair loss, causes the production of natural vaginal lubrication, while preventing dryness and discomfort during intercourse, and also prevents the development of such serious diseases like osteoporosis and atherosclerosis. In addition, estradiol helps to eliminate the specific manifestations of menopause and castration syndrome, such as flushing, sleep disturbance, sweating, dizziness, excessive irritability and irritability, cephalgia, atrophy of the mucous membranes and skin.
Dydrogesterone is a progesterone hormone that provides endometrial growth in the second part of the menstrual cycle. This hormonal substance in the composition of the drug “Femoston 2/10” reduces the risk of occurrence of the phenomena of endometrial hyperplasia and cancer of the uterus, the risk of developing which increases with the use of estrogen. This progesterone hormone does not have other effects, and is included in the composition of this medication specifically to level the likelihood of overgrowth and endometrial cancer.
What else does the instruction manual for “Femoston 2/10” tell us?
Indications for use
Climax significantly changes a woman’s life, violates plans, but there are certain methods of hormone replacement therapy that are designed specifically to eliminate these negative phenomena. Climax is not a disease, but it is very successfully treated. Currently, alternative non-hormonal methods are actively used, for example, the correction of the effects of menopause with the help of some herbal preparations, as well as homeopathic and other means. Nevertheless, experts consider hormones to be the most effective, since they are able to act directly on the root cause of various menopausal disorders.
According to the instructions for use for "Femoston 2/10" indications for the use of the drug are considered to be:
- Hormone replacement therapy for specific menopausal symptoms, as well as castration syndrome, which are manifested by hot flashes, increased palpitations, sweating, sleep disturbances, excessive irritability and nervousness, dryness of the vaginal mucosa, and other symptoms of estrogen hormone deficiency. Femoston 2/10 tablets can be started to be drunk already six months after the last menstruation.
- Prevention of the development of osteoporosis and thinning of bone tissue in women during menopause with intolerance to some other drugs that are designed to maintain the natural mineralization of bones, as well as for the prevention of calcium deficiency and the treatment of such a pathology.
Reviews of women after 40 about “Femoston 2/10” are mostly positive.
Ways to use the medication
The medication should be taken 1 tablet daily, and it is recommended to do this at the prescribed time. In each pack of the drug, all pink tablets are taken first, and then yellow, also one at a time.
Taking this medicine does not depend on meals. After the end of the pack of tablets, immediately begin to use the following, that is, the use of the drug is continuous. How to take "Femoston 2/10", you can check with your doctor.
If on a certain day a woman forgot to drink another tablet of the drug “Femoston”, but less than 12 hours have passed from the last administration, then she should be drunk as soon as possible. If more than 12 hours have passed from that moment, then the tablet should be skipped, and from the next day, start taking the drug in the usual way. It is not recommended to take two pills at the same time in order to compensate for skipping. If a tablet is missed, then during the application of the current package of the drug, the woman increases the risk of uterine bleeding or spotting.
The duration of the use of “Femoston 2/10” is determined in each case individually, depending on how quickly the patient's condition normalizes, and menopausal symptoms disappear. Usually a drug is used for at least 3-6 months continuously.
This medication is suitable for long-term continuous use, which means that tablets can be taken for several years without a break. Depending on how a woman feels, as well as on how effective the treatment is, this medication can be changed, only for a start you should finish the started packaging of the medicine. Then, again, without interruption, on the next day after the last pill of an estrogen-progestogen agent, you should start taking Femoston in a different dosage.
Women who have not stopped their periods should start taking the medicine on the first day of their period. If the cycle is irregular, then before using this medication, you should take medications containing progestogens within 14 days. Such medicines include Veraplex, Gormofort, Gestanin, Levonova, Dufaston, etc. These funds will provide the occurrence of withdrawal bleeding in order to remove endometrial residues from the uterus. If menstrual bleeding stopped in a woman more than 6 months ago, then you can start using the drug "Femoston" on any desired day.
Typically, such hormone replacement treatment begins, as a rule, with the drug "Femoston 1/10". And then, depending on how a woman responds to this organism, they leave the medicine or transfer to the use of the drug “Femoston 1/5” or “Femoston 2/10”.
If a woman has a desire to switch to another medication containing 2 or 3 types of tablets, then it is necessary to finish the packaging of the drug that has been started, and then, the next day, without interruption, another medication should be started.
If a woman wants to switch to taking the drug “Femoston 1/10” or “2/10” from any other pharmacological drug that contains only one kind of tablets, then this can be done at any time. Thus, there is no need to finish the packaging of another drug to the end. It is enough to do this any day at the request of the woman.
Special instructions for using the medication
In accordance with the instructions, "Femoston 2/10" is contraindicated for use during pregnancy, as well as during lactation. In cases when, against the background of the use of the drug, pregnancy accidentally occurs, then immediately stop using it and consult a gynecologist. At the same time, the issue of maintaining this pregnancy must be decided individually with a narrow specialist.
According to the instructions and reviews on "Femoston 2/10", the hormone estrogen can contribute to fluid retention in the body, as well as swelling of the extremities, then this pharmaceutical should be prescribed with caution to women who suffer from chronic kidney pathologies, as well as patients with renal failure or some heart ailments.
During the entire course of therapy with this medication, the functional qualities of the kidneys and heart should be carefully monitored, as well as the general condition of the woman. Reviews about "Femoston 2/10" with menopause will also be given at the end of the article.
The drug is not recommended for use by people who suffer from any chronic or acute liver pathologies of any degree. “Femoston 1/10” and “Femoston 1/5” for these diseases are allowed to be used only after liver tests in laboratory tests return to normal. In this case, the activity of alkaline phosphatase, as well as AlAT, AsAT, is evaluated.
Against the background of the use of the Femoston medication, it is necessary to visit a gynecologist at least once a year, who must assess the risk and benefit of the action of the drug, and also relate them to each other. After that, on the basis of the data obtained, make a decision about whether to continue the replacement therapy with this hormonal agent or whether it should be stopped.
The use of any kind of the drug “Femoston” is continued until the beneficial effects of such treatment exceed the risks. Before using it, it is necessary to carefully diagnose all current and transferred diseases, as well as examine the condition of the woman's genitals and visit a mammologist to assess the condition of the mammary glands. If there are any neoplasms in the uterus, on the ovaries or in the tissues of the mammary glands of a benign nature, then the Femoston medication should not be taken categorically. If during the hormone replacement treatment with this drug in the chest there is any formation of nodes or seals, you should immediately contact a doctor.
During the entire period of substitution therapy with the Femoston medication, women suffering in the present time or having suffered some diseases in the past are recommended to see a doctor once every three months. Such pathologies include:
- Uterine fibroids.
- High risk of thrombosis or thromboembolism, previous thrombosis of deep or saphenous veins of the lower extremities.
- Endometriosis
- The presence of breast cancer in close relatives by blood (mother, sister, grandmother, etc.).
- Hypertonic disease.
- Diabetes.
- Hepatocellular adenoma.
- Severe forms of obesity.
- Cholelithiasis.
- Migraine.
- Severe forms of cephalgia.
- Systemic lupus erythematosus.
- Porphyria.
- Endometrial hyperplasia.
- Epilepsy.
- Otosclerosis.
- Bronchial asthma.
- Multiple sclerosis.
In women suffering from the aforementioned diseases in the present or past tense, while taking the drug “Femoston”, the symptoms of these pathological conditions have some property of increasing. With these diseases, a woman significantly increases the likelihood of developing certain complications of hormone replacement treatment, such as, for example, malignant neoplasms in the mammary gland, thromboembolism, stroke, heart attack, coronary heart disease, etc. That is why a similar category of women must be systematically controlled his condition, as well as analysis indicators for some pathologies, visiting a specialist once a quarter. Reviews on "Femoston 2/10" also confirm this information.
The risk of developing certain diseases while taking the medication
In addition, you should be aware that taking a drug or other medication for hormone replacement therapy containing the hormone estrogen increases the likelihood of developing cancer of the endometrium and mammary gland several times. Therefore, women should be extremely careful about the possible occurrence of this dangerous disease during the entire period of use of the drug Femoston. The likelihood of cancer is higher, the longer the data is used medical tool. In addition, against the background of its use in women, the likelihood of a stroke and coronary heart disease increases. Nevertheless, this also affects the woman’s age and the chronic pathologies that are observed in her, but the occurrence of these conditions does not depend on the duration of use of this hormonal drug.
The most pronounced increase in the likelihood of venous thromboembolism against the background of the use of the drug Femoston is the most relevant during the first year of using this medication, and in subsequent years this risk gradually begins to decrease. Therefore, patients with a high predisposition to venous thromboembolism can take the drug "Femoston" only with the permission of a specialist and under his strict supervision. If blood relatives have any thrombolytic defects, for example, a deficiency of antithrombin, protein S or protein C, then the woman is not recommended to take this hormonal drug.
Since any extensive surgical operations are associated with a risk of thromboembolism, it is necessary to stop the use of the drug “Femoston” several weeks before such interventions. It is possible to resume the use of the medication after the patient's motor activity is completely restored after the surgical intervention.
During therapy with the drug "Femoston 2/10" in the blood, there may be an increase in the concentration of triglycerides, corticoid-binding globulin, thyroid-binding globulin, globulin, which binds sex hormones, as well as ceruloplasmin and alpha-1-antitrypsin. Nevertheless, this does not lead to an increase in the concentration of active hormones circulating in the blood. According to reviews, “Femoston 2/10”, despite this, is well tolerated.
Use with caution
The drug is not a medication for contraception. At the beginning of therapy with this substitution treatment, a woman may experience breakthrough bleeding or spotting. .
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Side effects
"Femoston 2/10" can provoke some side effects. These include:
- migraine;
- asthenia;
- headache;
- pain in the abdomen;
- flatulence;
- spasm in the calf muscles;
- breast tenderness;
- spotting;
- uterine bleeding;
- change in body weight;
- vaginal candidiasis;
- an increase in the size of uterine fibroids;
- nervousness and depressive disorders;
- change in libido;
- venous thromboembolism;
- back and lower back pain;
- cholelithiasis;
- allergic symptoms
- swelling
- pseudo-erosion and erosion of the cervix;
- increased keratoconus;
- lens intolerance;
- breast enlargement;
- chorea;
- premenstrual syndrome;
- stroke and myocardial infarction;
- hemolytic anemia;
- violations in the liver and kidneys;
- Quincke's edema;
- erythema nodosum;
- chloasma or melasma;
- vascular purpura.
Reviews about the drug
Consider first the reviews of women about "Femoston 2/10". It is considered a very serious hormonal drug, which should be used only in case of emergency and with the appointment of a specialist. In connection with this circumstance, there are not so many reviews about this drug.
Some patients who used this drug for menopause note that under the influence of the hormones included in its composition, they observed a significant reduction in the unpleasant phenomena associated with this period, in the form of heat in the face, general malaise and weakness, cephalgia, etc. The drug, in their opinion, is very effective, but many women try not to use because of the many contraindications and side effects. Due to the fact that this medicine increases the likelihood of developing oncology of female organs, it is extremely rarely used in the treatment of hormonal pathologies in women of reproductive age, trying to replace the medication with more gentle hormonal agents. This is evidenced by the numerous reviews of women about "Femoston 2/10."
Nevertheless, in most cases, it is noted in the reviews that the drug of this type is relatively well tolerated, especially after a certain time after the start of its intake, which is probably due to the body’s getting used to hormonal substances that enter inside.
There are also other plans for reviews of “Femoston 2/10”. When planning pregnancy, about half of all patients this drug helped in the treatment of infertility. This is also indicated by gynecologists, who often prescribe the hormonal drug "Femoston" in their medical practice in the treatment of women who have difficulty conceiving. Nevertheless, doctors try not to prescribe this medication, since its use often leads to no less dangerous consequences, and it is usually prescribed only in cases of emergency when other medications are ineffective.
Doctors reviews
Now consider what the experts think about this drug.
According to doctors, “Femoston 2/10” is a very effective remedy. Especially if it is prescribed at the stages of pregnancy planning. But it is recommended that women take it with caution, since side effects may occur.
Patients who used the medication indicate the frequent occurrence of some side effects from the digestive tract, central nervous system, as well as the development of allergic reactions in the form of urticaria, skin rashes, etc. Many had unbearable headache, vomiting, pain in abdominal diarrhea. A certain part of the patients noted the occurrence of seals in the mammary glands, as a result of which they had to stop using the medicine, after which these phenomena disappeared spontaneously. In addition, all women observed a slight increase in breast size and tension in the glands before menstruation.
We reviewed the drug "Femoston 2/10" instructions and reviews. We hope the information provided will be useful to the reader.